EPA Consensus Project Paper: The Influence of Prosthetic Factors on the Incidence of Peri-implantitis Around Single Implants: A Systematic Review.

INTRODUCTION The purpose of this systematic review was to evaluate how prosthetic factors affect the incidence of peri-implantitis in patients treated with single implant restorations. METHODS Electronic and manual search of two indexed databases up to April 2023 were conducted, to identify clinical studies reporting on the effect of different prosthetic factors on the incidence of peri-implantitis around single implants and with at least 1 year follow-up. The risk of bias was assessed with the Joanna Briggs Institute critical appraisal checklist, the ROB2 and the ROBINS-I tools. RESULTS From the 521 screened articles, 11 studies (1 randomized controlled trial, 7 cross-sectional, 3 retrospective) met the inclusion criteria. Based on three studies, emergence angle⟩30°, convex emergence profile and external connection are associated with a higher incidence of peri-implantitis. Nine studies pertaining to the effect of retention type on the prevalence of peri-implantitis reported conflicting results. Six out of eleven included studies presented some risk of bias. CONCLUSIONS There is insufficient evidence regarding the influence of prosthetic factors on the incidence of peri-implantitis around single implants. Further studies are needed to draw definitive conclusions on this issue.

[1]  D. E. Slot,et al.  Implant‐abutment emergence angle and profile in relation to peri‐implantitis: A systematic review , 2022, Clinical and experimental dental research.

[2]  Stephanie Pekarski,et al.  Impact of design elements of the implant supracrestal complex (ISC) on the risk of peri-implant mucositis and peri-implantitis: A critical review. , 2021, Clinical oral implants research.

[3]  J. Albandar,et al.  Prevalence and risk indicators of peri-implant diseases in a group of moroccan patients. , 2020, Journal of periodontology.

[4]  A. V. van Winkelhoff,et al.  Influence of Cervical Crown Contour on Marginal Bone Loss Around Platform-Switched Bone-Level Implants: A 5-Year Cross-Sectional Study. , 2020, The International journal of prosthodontics.

[5]  M. Sanz,et al.  Prevalence and risk/protective indicators of peri-implant diseases: a university-representative cross-sectional study , 2020, medRxiv.

[6]  Konstantinos Chochlidakis,et al.  Peri-Implant Diseases and Biologic Complications at Implant-Supported Fixed Dental Prostheses in Partially Edentulous Patients. , 2020, Journal of prosthodontics : official journal of the American College of Prosthodontists.

[7]  F. Carinci,et al.  The Impact of Implant–Abutment Connection on Clinical Outcomes and Microbial Colonization: A Narrative Review , 2020, Materials.

[8]  S. Heo,et al.  Association of prosthetic features and peri-implantitis: A cross-sectional study. , 2020, Journal of clinical periodontology.

[9]  Huajie Yu,et al.  Influence of crown-to-implant ratio and different prosthetic designs on the clinical conditions of short implants in posterior regions: A 4-year retrospective clinical and radiographic study. , 2020, Clinical implant dentistry and related research.

[10]  Jun-Beom Park Peri-implantitis , 2019, Dental Abstracts.

[11]  D. Torres-Lagares,et al.  Influence of marginal bone loss on peri-implantitis: Systematic review of literature , 2019, Journal of clinical and experimental dentistry.

[12]  J. Sterne,et al.  Assessing risk of bias in a randomized trial , 2019, Cochrane Handbook for Systematic Reviews of Interventions.

[13]  C. Ardila,et al.  Gram-negative enteric rods/Pseudomonas colonization in mucositis and peri-implantitis of implants restored with cemented and screwed reconstructions: A cross-sectional study. , 2019, Clinical implant dentistry and related research.

[14]  M. Wada,et al.  Prevalence of peri‐implant disease and risk indicators in a Japanese population with at least 3 years in function—A multicentre retrospective study , 2019, Clinical oral implants research.

[15]  M. Zwahlen,et al.  A systematic review of the influence of the implant‐abutment connection on the clinical outcomes of ceramic and metal implant abutments supporting fixed implant reconstructions , 2018, Clinical oral implants research.

[16]  Irena Sailer,et al.  A systematic review of the survival and complication rates of zirconia‐ceramic and metal‐ceramic single crowns , 2018, Clinical oral implants research.

[17]  A. Cucchi,et al.  The influence of implant‐abutment connection to peri‐implant bone loss: A systematic review and meta‐analysis , 2018, Clinical implant dentistry and related research.

[18]  J. Lorenz,et al.  Screw-retained monolithic zirconia vs. cemented porcelain-fused-to-metal implant crowns: a prospective randomized clinical trial in split-mouth design , 2018, Clinical Oral Investigations.

[19]  G. Huynh-Ba,et al.  Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. , 2018, Journal of clinical periodontology.

[20]  G. Huynh-Ba,et al.  Peri-implant diseases and conditions: Consensus report of workgroup 4 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. , 2018, Journal of periodontology.

[21]  C. Walter,et al.  Excess cement and the risk of peri‐implant disease – a systematic review , 2017, Clinical oral implants research.

[22]  C. Feng,et al.  Influence of Apico‐Coronal Implant Placement on Post‐Surgical Crestal Bone Loss in Humans , 2017, Journal of periodontology.

[23]  Liang Zhu,et al.  Prevalences of peri-implantitis and peri-implant mucositis: systematic review and meta-analysis. , 2017, Journal of dentistry.

[24]  V. Perrotti,et al.  The Impact of Residual Subgingival Cement on Biological Complications Around Dental Implants: A Systematic Review , 2017, Implant dentistry.

[25]  S. Renvert,et al.  Risk indicators for Peri‐implantitis. A cross‐sectional study with 916 implants , 2017, Clinical oral implants research.

[26]  M. Hernán,et al.  ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions , 2016, British Medical Journal.

[27]  E. Pellizzer,et al.  Evaluation of cement-retained versus screw-retained implant-supported restorations for marginal bone loss: A systematic review and meta-analysis. , 2016, The Journal of prosthetic dentistry.

[28]  G. Kotsakis,et al.  Investigation of the Association Between Cement Retention and Prevalent Peri-Implant Diseases: A Cross-Sectional Study. , 2016, Journal of periodontology.

[29]  Jorge Pereira,et al.  Morse taper dental implants and platform switching: The new paradigm in oral implantology , 2016, European journal of dentistry.

[30]  T. Linkevicius,et al.  Influence of Vertical Soft Tissue Thickness on Crestal Bone Changes Around Implants with Platform Switching: A Comparative Clinical Study. , 2015, Clinical implant dentistry and related research.

[31]  H. De Bruyn,et al.  Systematic review of some prosthetic risk factors for periimplantitis. , 2015, The Journal of prosthetic dentistry.

[32]  R. Genco,et al.  Primary prevention of peri-implantitis: managing peri-implant mucositis. , 2015, Journal of clinical periodontology.

[33]  D. Daubert,et al.  Prevalence and predictive factors for peri-implant disease and implant failure: a cross-sectional analysis. , 2015, Journal of periodontology.

[34]  A. Catena,et al.  Influence of crown/implant ratio on marginal bone loss: a systematic review. , 2014, Journal of periodontology.

[35]  M. Vettore,et al.  Peri-implant bone loss in cement- and screw-retained prostheses: systematic review and meta-analysis. , 2013, Journal of clinical periodontology.

[36]  M. Zwahlen,et al.  Cemented and screw-retained implant reconstructions: a systematic review of the survival and complication rates. , 2012, Clinical oral implants research.

[37]  Daniel S. Thoma,et al.  Systematic review of the survival rate and the incidence of biological, technical, and aesthetic complications of single crowns on implants reported in longitudinal studies with a mean follow-up of 5 years. , 2012, Clinical oral implants research.

[38]  T. Linkevicius,et al.  Does residual cement around implant-supported restorations cause peri-implant disease? A retrospective case analysis. , 2012, Clinical oral implants research.

[39]  J. Ioannidis,et al.  The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration , 2009, Annals of Internal Medicine [serial online].

[40]  L. Francetti,et al.  Medium- and Long-Term Survival Rates of Implant-Supported Single and Partial Restorations at a Maximum Follow-up of 12 Years: A Retrospective Study. , 2021, The International journal of prosthodontics.

[41]  C. Tufanaru,et al.  Chapter 7: Systematic Reviews of Etiology and Risk , 2020, JBI Manual for Evidence Synthesis.

[42]  U. Brägger,et al.  Influence of prosthesis type and retention mechanism on complications with fixed implant-supported prostheses: a systematic review applying multivariate analyses. , 2015, The International journal of oral & maxillofacial implants.

[43]  U. Brägger,et al.  Clinical performance of screw- versus cement-retained fixed implant-supported reconstructions--a systematic review. , 2014, The International journal of oral & maxillofacial implants.

[44]  J. Higgins Cochrane handbook for systematic reviews of interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration , 2011 .

[45]  D. Moher,et al.  Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. , 2010, International journal of surgery.