Stem-cell-based therapy and lessons from the heart

[1]  Ronald A. Li,et al.  Functional sarcoplasmic reticulum for calcium-handling of human embryonic stem cell-derived cardiomyocytes: Insights for driven maturation , 2008, Cell Research.

[2]  P. Menasché,et al.  Cardiac stem cells in the real world. , 2008, The Journal of thoracic and cardiovascular surgery.

[3]  C. Mummery,et al.  Origins and Fates of Cardiovascular Progenitor Cells , 2008, Cell.

[4]  Marius Wernig,et al.  Treatment of Sickle Cell Anemia Mouse Model with iPS Cells Generated from Autologous Skin , 2007, Science.

[5]  Shulan Tian,et al.  Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2007, Science.

[6]  Guy Salama,et al.  Engraftment of connexin 43-expressing cells prevents post-infarct arrhythmia , 2007, Nature.

[7]  Ying Meng,et al.  Differentiation and Enrichment of Hepatocyte‐Like Cells from Human Embryonic Stem Cells In Vitro and In Vivo , 2007, Stem cells.

[8]  Ulrich H. von Andrian,et al.  Immunosurveillance by Hematopoietic Progenitor Cells Trafficking through Blood, Lymph, and Peripheral Tissues , 2007, Cell.

[9]  T. Ichisaka,et al.  Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors , 2007, Cell.

[10]  Jae Min Lim,et al.  Improvement of Postnatal Neovascularization by Human Embryonic Stem Cell–Derived Endothelial-Like Cell Transplantation in a Mouse Model of Hindlimb Ischemia , 2007, Circulation.

[11]  Rafael Beyar,et al.  Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts. , 2007, Journal of the American College of Cardiology.

[12]  Chris Denning,et al.  Transgenic enrichment of cardiomyocytes from human embryonic stem cells. , 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

[13]  M. Miragoli,et al.  Myofibroblasts Induce Ectopic Activity in Cardiac Tissue , 2007, Circulation research.

[14]  G. Hasenfuss,et al.  Do stem cells in the heart truly differentiate into cardiomyocytes? , 2007, Journal of molecular and cellular cardiology.

[15]  Robert Passier,et al.  Monitoring of cell therapy and assessment of cardiac function using magnetic resonance imaging in a mouse model of myocardial infarction , 2007, Nature Protocols.

[16]  K. Endresen,et al.  Exercise capacity and quality of life after intracoronary injection of autologous mononuclear bone marrow cells in acute myocardial infarction: results from the Autologous Stem cell Transplantation in Acute Myocardial Infarction (ASTAMI) randomized controlled trial. , 2007, American heart journal.

[17]  R. Kloner,et al.  Survival and maturation of human embryonic stem cell-derived cardiomyocytes in rat hearts. , 2007, Journal of molecular and cellular cardiology.

[18]  S. Nishikawa,et al.  Pathway for Differentiation of Human Embryonic Stem Cells to Vascular Cell Components and Their Potential for Vascular Regeneration , 2007, Arteriosclerosis, thrombosis, and vascular biology.

[19]  P. Doevendans,et al.  Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction. , 2007, Stem cell research.

[20]  J. Leor,et al.  Iron-Oxide Labeling and Outcome of Transplanted Mesenchymal Stem Cells in the Infarcted Myocardium , 2007, Circulation.

[21]  G. Whitesides,et al.  Muscular Thin Films for Building Actuators and Powering Devices , 2007, Science.

[22]  Jianyi(Jay) Zhang,et al.  Functional and bioenergetic modulations in the infarct border zone following autologous mesenchymal stem cell transplantation. , 2007, American journal of physiology. Heart and circulatory physiology.

[23]  Lila R Collins,et al.  Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts , 2007, Nature Biotechnology.

[24]  D. Atsma,et al.  Preservation of Left Ventricular Function and Attenuation of Remodeling After Transplantation of Human Epicardium-Derived Cells Into the Infarcted Mouse Heart , 2007, Circulation.

[25]  S. E. Jacobsen,et al.  Potential risks of bone marrow cell transplantation into infarcted hearts. , 2007, Blood.

[26]  S. Gerecht,et al.  Vascular Progenitor Cells Isolated From Human Embryonic Stem Cells Give Rise to Endothelial and Smooth Muscle–Like Cells and Form Vascular Networks In Vivo , 2007, Circulation research.

[27]  L. Gepstein,et al.  Identification and selection of cardiomyocytes during human embryonic stem cell differentiation , 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[28]  A. Luttun,et al.  Multipotent adult progenitor cell transplantation increases vascularity and improves left ventricular function after myocardial infarction , 2007, Journal of tissue engineering and regenerative medicine.

[29]  S. Gerecht,et al.  Human embryonic stem cell transplantation to repair the infarcted myocardium , 2007, Heart.

[30]  Yu Chen,et al.  Generation of functional hemangioblasts from human embryonic stem cells , 2007, Nature Methods.

[31]  S. E. Kim,et al.  Directed differentiation of human embryonic stem cells towards a pancreatic cell fate , 2007, Diabetologia.

[32]  Cory Swingen,et al.  Bioenergetic and Functional Consequences of Bone Marrow-Derived Multipotent Progenitor Cell Transplantation in Hearts With Postinfarction Left Ventricular Remodeling , 2007, Circulation.

[33]  Piotr A Wielopolski,et al.  Intracoronary delivery of umbilical cord blood derived unrestricted somatic stem cells is not suitable to improve LV function after myocardial infarction in swine. , 2007, Journal of molecular and cellular cardiology.

[34]  R. Jain,et al.  Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo , 2007, Nature Biotechnology.

[35]  B. Sacchetti,et al.  Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells , 2007, Nature Cell Biology.

[36]  E. Marbán,et al.  Regenerative Potential of Cardiosphere-Derived Cells Expanded From Percutaneous Endomyocardial Biopsy Specimens , 2007, Circulation.

[37]  Shulamit Levenberg,et al.  Tissue Engineering of Vascularized Cardiac Muscle From Human Embryonic Stem Cells , 2007, Circulation research.

[38]  P. Doevendans,et al.  Progenitor cells for cardiac repair. , 2007, Seminars in cell & developmental biology.

[39]  Catherine A. Risebro,et al.  Thymosin β4 induces adult epicardial progenitor mobilization and neovascularization , 2007, Nature.

[40]  Liangbiao Chen,et al.  Differentiation of human embryonic stem cells into smooth muscle cells in adherent monolayer culture. , 2006, Biochemical and biophysical research communications.

[41]  Yunfu Sun,et al.  Multipotent Embryonic Isl1 + Progenitor Cells Lead to Cardiac, Smooth Muscle, and Endothelial Cell Diversification , 2006, Cell.

[42]  D. Clapham,et al.  In Brief , 2006, Nature Reviews Drug Discovery.

[43]  M. Goumans,et al.  Endoglin Has a Crucial Role in Blood Cell–Mediated Vascular Repair , 2006, Circulation.

[44]  R. Roberts,et al.  A Dynamic Epicardial Injury Response Supports Progenitor Cell Activity during Zebrafish Heart Regeneration , 2006, Cell.

[45]  Ralf Kettenhofen,et al.  Engraftment of engineered ES cell–derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium , 2006, The Journal of experimental medicine.

[46]  E. Taraldsrud,et al.  Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. , 2006, The New England journal of medicine.

[47]  A. Zeiher,et al.  Transcoronary transplantation of progenitor cells after myocardial infarction. , 2006, The New England journal of medicine.

[48]  A. Zeiher,et al.  Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. , 2006, The New England journal of medicine.

[49]  S. Yamanaka,et al.  Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors , 2006, Cell.

[50]  S. Verma,et al.  Cardioprotective c-kit+ cells are from the bone marrow and regulate the myocardial balance of angiogenic cytokines. , 2006, The Journal of clinical investigation.

[51]  Robert Passier,et al.  Genome‐Wide Transcriptional Profiling of Human Embryonic Stem Cells Differentiating to Cardiomyocytes , 2006, Stem cells.

[52]  Lil Pabon,et al.  Regeneration gaps: observations on stem cells and cardiac repair. , 2006, Journal of the American College of Cardiology.

[53]  Jonathan L. Linehan,et al.  Hematopoietic Engraftment of Human Embryonic Stem Cell‐Derived Cells Is Regulated by Recipient Innate Immunity , 2006, Stem cells.

[54]  Andreas Hess,et al.  Engineered heart tissue grafts improve systolic and diastolic function in infarcted rat hearts , 2006, Nature Medicine.

[55]  Keiichi Fukuda,et al.  Pulsatile Cardiac Tissue Grafts Using a Novel Three-Dimensional Cell Sheet Manipulation Technique Functionally Integrates With the Host Heart, In Vivo , 2006, Circulation research.

[56]  A. Zeiher,et al.  Bone-marrow-derived progenitor cell therapy in need of proof of concept: design of the REPAIR-AMI trial , 2006, Nature Clinical Practice Cardiovascular Medicine.

[57]  M. Rubart,et al.  Cardiac regeneration: repopulating the heart. , 2006, Annual review of physiology.

[58]  S. Dymarkowski,et al.  Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial , 2006, The Lancet.

[59]  Emmanuel Messas,et al.  Transplantation of cardiac-committed mouse embryonic stem cells to infarcted sheep myocardium: a preclinical study , 2005, The Lancet.

[60]  Chunhui Xu,et al.  Formation of human myocardium in the rat heart from human embryonic stem cells. , 2005, The American journal of pathology.

[61]  M. Ballmaier,et al.  Haematopoietic stem cells improve cardiac function after infarction without permanent cardiac engraftment , 2005, European journal of heart failure.

[62]  C. Bearzi,et al.  Human Cardiac Stem Cells , 2005, Microscopy and Microanalysis.

[63]  S. Goldman Stem and progenitor cell–based therapy of the human central nervous system , 2005, Nature Biotechnology.

[64]  Robert Passier,et al.  Increased Cardiomyocyte Differentiation from Human Embryonic Stem Cells in Serum‐Free Cultures , 2005, Stem cells.

[65]  J. Ingwall,et al.  Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells , 2005, Nature Medicine.

[66]  U. Ikeda,et al.  Repair of Infarcted Myocardium Mediated by Transplanted Bone Marrow–Derived CD34+ Stem Cells in a Nonhuman Primate Model , 2005, Stem cells.

[67]  J. Epstein,et al.  Pursuing Cardiac Progenitors: Regeneration Redux , 2005, Cell.

[68]  Karl-Ludwig Laugwitz,et al.  Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages , 2005, Nature.

[69]  Steven P Jones,et al.  Functional Integration of Electrically Active Cardiac Derivatives From Genetically Engineered Human Embryonic Stem Cells With Quiescent Recipient Ventricular Cardiomyocytes: Insights Into the Development of Cell-Based Pacemakers , 2005, Circulation.

[70]  D. Kaufman,et al.  Human embryonic stem cell-derived hematopoietic cells are capable of engrafting primary as well as secondary fetal sheep recipients. , 2004, Blood.

[71]  Giulio Cossu,et al.  Isolation and Expansion of Adult Cardiac Stem Cells From Human and Murine Heart , 2004, Circulation research.

[72]  Rona Shofti,et al.  Electromechanical integration of cardiomyocytes derived from human embryonic stem cells , 2004, Nature Biotechnology.

[73]  B. Fleischmann,et al.  Bone marrow–derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation , 2004, Nature Medicine.

[74]  David A. Williams,et al.  Haematopoietic stem cells do not transdifferentiate into cardiac myocytes in myocardial infarcts , 2004, Nature.

[75]  I. Weissman,et al.  Haematopoietic stem cells adopt mature haematopoietic fates in ischaemic myocardium , 2004, Nature.

[76]  Michael D. Schneider,et al.  Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[77]  D. Torella,et al.  Adult Cardiac Stem Cells Are Multipotent and Support Myocardial Regeneration , 2003, Cell.

[78]  Clotilde Castaldo,et al.  Intense myocyte formation from cardiac stem cells in human cardiac hypertrophy , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[79]  James A Thomson,et al.  Human Embryonic Stem Cells Develop Into Multiple Types of Cardiac Myocytes: Action Potential Characterization , 2003, Circulation research.

[80]  M. Hoehn,et al.  Host-Dependent Tumorigenesis of Embryonic Stem Cell Transplantation in Experimental Stroke , 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[81]  M. Rubart,et al.  Physiological Coupling of Donor and Host Cardiomyocytes After Cellular Transplantation , 2003, Circulation research.

[82]  E. Audinat,et al.  Myoblasts transplanted into rat infarcted myocardium are functionally isolated from their host , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[83]  Rene Spijker,et al.  Differentiation of Human Embryonic Stem Cells to Cardiomyocytes: Role of Coculture With Visceral Endoderm-Like Cells , 2003, Circulation.

[84]  Kenneth W Dunn,et al.  Two-photon molecular excitation imaging of Ca2+ transients in Langendorff-perfused mouse hearts. , 2003, American journal of physiology. Cell physiology.

[85]  A. Hagège,et al.  Long-Term Efficacy of Myoblast Transplantation on Regional Structure and Function After Myocardial Infarction , 2002, Circulation.

[86]  Chunhui Xu,et al.  Characterization and Enrichment of Cardiomyocytes Derived From Human Embryonic Stem Cells , 2002, Circulation research.

[87]  G. Spangrude,et al.  Chimerism of the transplanted heart. , 2002, The New England journal of medicine.

[88]  Shulamit Levenberg,et al.  Endothelial cells derived from human embryonic stem cells , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[89]  L Gepstein,et al.  Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. , 2001, The Journal of clinical investigation.

[90]  D. Sawyer,et al.  Cell Therapy Attenuates Deleterious Ventricular Remodeling and Improves Cardiac Performance After Myocardial Infarction , 2001, Circulation.

[91]  David M. Bodine,et al.  Bone marrow cells regenerate infarcted myocardium , 2001, Nature.

[92]  H. Blau,et al.  From marrow to brain: expression of neuronal phenotypes in adult mice. , 2000, Science.

[93]  C. Murry,et al.  Survival, integration, and differentiation of cardiomyocyte grafts: a study in normal and injured rat hearts. , 1999, Circulation.

[94]  J. Thomson,et al.  Embryonic stem cell lines derived from human blastocysts. , 1998, Science.

[95]  J. Cohn,et al.  Prognostic Significance of Serial Changes in Left Ventricular Ejection Fraction in Patients With Congestive Heart Failure , 1993, Circulation.

[96]  Takashi Aoi,et al.  Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts , 2008, Nature Biotechnology.

[97]  B. Thiers Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells , 2008 .

[98]  T. Maddox,et al.  Cell therapy for cardiac disease: where do we go from here? , 2007, Nature Clinical Practice Cardiovascular Medicine.

[99]  J. Thomson,et al.  Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells , 2004, Nature Biotechnology.

[100]  Daniel J Garry,et al.  Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart. , 2004, Developmental biology.

[101]  A. Katz,et al.  Evidence that human cardiac myocytes divide after myocardial infarction. , 2001, The New England journal of medicine.