Comparative analysis of p53 and c-myc expression and cell proliferation in human hepatocellular carcinomas-an enhanced immunohistochemical approach

[1]  Y. Fukuda,et al.  Expression of oncogenes in human liver disease. , 2008, Liver.

[2]  P. Friedman,et al.  Wild-type p53 activates transcription in vitro , 1992, Nature.

[3]  K. Okuda,et al.  Hepatocellular carcinoma: Recent progress , 1992, Hepatology.

[4]  H. Sasano,et al.  Immunolocalization of c-myc oncoprotein in mucinous and serous adenocarcinomas of the ovary. , 1992, Human pathology.

[5]  C. Borner,et al.  c-myc protein distribution. Neoplastic tissues of the human colon. , 1992, The American journal of pathology.

[6]  Y. Miyoshi,et al.  Immunohistochemical study of p53 expression in microwave-fixed, paraffin-embedded sections of colorectal carcinoma and adenoma. , 1992, American journal of clinical pathology.

[7]  M. Yaniv,et al.  Wild-type p53 can down-modulate the activity of various promoters. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[8]  S. Hirohashi,et al.  Aberrations of the tumor suppressor p53 and retinoblastoma genes in human hepatocellular carcinomas. , 1991, Cancer research.

[9]  M. Key,et al.  Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections. , 1991, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[10]  T. Iwama,et al.  p53 gene mutations in colorectal tumors from patients with familial polyposis coli. , 1991, Cancer research.

[11]  Y. Nakamura,et al.  Frequent loss of heterozygosity on chromosomes 1q, 5q, and 17p in human gastric carcinomas. , 1991, Cancer research.

[12]  J. Marks,et al.  Maintenance of p53 alterations throughout breast cancer progression. , 1991, Cancer research.

[13]  E. Appella,et al.  Growth suppression induced by wild-type p53 protein is accompanied by selective down-regulation of proliferating-cell nuclear antigen expression. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[14]  C. Marshall.  Tumor suppressor genes , 1991, Cell.

[15]  M. Noguchi,et al.  Immunohistochemical demonstration of epidermal growth factor and c‐myc oncogene product in normal, benign and malignant thyroid tissues , 1991, Histopathology.

[16]  D. Lane,et al.  Proliferating cell nuclear antigen (PCNA) immunolocalization in paraffin sections: An index of cell proliferation with evidence of deregulated expression in some, neoplasms , 1990, The Journal of pathology.

[17]  S. Fields,et al.  Presence of a potent transcription activating sequence in the p53 protein. , 1990, Science.

[18]  D. Brenner,et al.  Transient induction of C‐jun during hepatic regeneration , 1990, Hepatology.

[19]  A. Wyllie,et al.  Immunohistochemical demonstration of altered intracellular localization of the c‐Myc oncogene product in human colorectal neoplasms , 1990, The Journal of pathology.

[20]  K. Isselbacher,et al.  Abnormal structure and expression of p53 gene in human hepatocellular carcinoma. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[21]  S. Hirohashi,et al.  Frequent Loss of Heterozygosity on Chromosomes 16 and 4 in Human Hepatocellular Carcinoma , 1990, Japanese journal of cancer research : Gann.

[22]  K. Buetow,et al.  Loss of heterozygosity suggests tumor suppressor gene responsible for primary hepatocellular carcinoma. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[23]  A. Levine,et al.  The p53 proto-oncogene can act as a suppressor of transformation , 1989, Cell.

[24]  S. Thorgeirsson,et al.  Poly(A+)RNA levels of growth‐, differentiation‐ and transformation‐associated genes in the progressive development of hepatocellular carcinoma in the rat , 1989, Hepatology.

[25]  A. Tigges,et al.  Expression of the nuclear oncogene p53 in colon tumours , 1989, The Journal of pathology.

[26]  C. Bréchot,et al.  Regional mapping to 4q32.1 by in situ hybridization of a DNA domain rearranged in human liver cancer , 1988, Human Genetics.

[27]  S. Thorgeirsson,et al.  Cellular distribution of c-myc transcripts during chemical hepatocarcinogenesis in rats. , 1988, Cancer research.

[28]  E. Jaffe,et al.  c-myc protein in normal tissue. Effects of fixation on its apparent subcellular distribution. , 1988, The American journal of pathology.

[29]  A. Levine,et al.  Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life , 1988, Molecular and cellular biology.

[30]  J. Calvet,et al.  Elevated c-myc protooncogene expression in autosomal recessive polycystic kidney disease. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[31]  A. Ghosh,et al.  A critical appraisal of the immunohistochemical detection of the c-myc oncogene product in colorectal cancer. , 1987, British Journal of Cancer.

[32]  R. Bravo,et al.  Cyclin/PCNA is the auxiliary protein of DNA polymerase-δ , 1987, Nature.

[33]  Y. Shimosato,et al.  The AMeX method. A simplified technique of tissue processing and paraffin embedding with improved preservation of antigens for immunostaining. , 1986, The American journal of pathology.

[34]  Toshimitsu Suzuki,et al.  lmmunohistochemical demonstration of c-myc gene product in tumors induced in nude mice by human hepatoblastoma: A study with antiserum to a related synthetic peptide , 1986 .

[35]  N. Glaichenhaus.  [Cooperation between oncogenes: the function of immortalizing oncogenes]. , 1986, Pathologie-biologie.

[36]  T. Iwanaga,et al.  IMMUNOCYTOCHEMICAL DETECTION OF THE c-myc ONCOGENE PRODUCT IN HUMAN FETUSES , 1986 .

[37]  J. Stewart,et al.  Detection of the c-myc oncogene product in colonic polyps and carcinomas. , 1986, British Journal of Cancer.

[38]  J. Celis,et al.  Cell cycle-dependent variations in the distribution of the nuclear protein cyclin proliferating cell nuclear antigen in cultured cells: subdivision of S phase. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[39]  T. Sugimura,et al.  C-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment , 1984, Nature.

[40]  B. Franza,et al.  Identity of the proliferating cell nuclear antigen and cyclin , 1984, Nature.

[41]  I. Verma,et al.  Expression of cellular oncogenes in human malignancies. , 1984, Science.

[42]  T. Sugimura,et al.  Expressions of the c-Ha-ras and c-myc genes in rat liver tumors. , 1984, Biochemical and biophysical research communications.

[43]  P. Leder,et al.  Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor , 1983, Cell.

[44]  P. Leder,et al.  Translocations among antibody genes in human cancer. , 1983, Science.

[45]  A. Gown,et al.  Widespread p53 overexpression in human malignant tumors. An immunohistochemical study using methacarn-fixed, embedded tissue. , 1992, The American journal of pathology.

[46]  R. Metcalf,et al.  Mutational hotspot in the p53 gene in human hepatocellular carcinomas. , 1991, Nature.

[47]  Carl W. Miller,et al.  Human p53 gene localized to short arm of chromosome 17 , 1986, Nature.