Targeting tumour-associated macrophages in hodgkin lymphoma using engineered extracellular matrix-mimicking cryogels.

[1]  J. Qiao,et al.  The STAT6 inhibitor AS1517499 reduces the risk of asthma in mice with 2,4-dinitrochlorobenzene-induced atopic dermatitis by blocking the STAT6 signaling pathway , 2022, Allergy, Asthma & Clinical Immunology.

[2]  A. McGuigan,et al.  3D microgels to quantify tumor cell properties and therapy response dynamics. , 2022, Biomaterials.

[3]  J. Zak,et al.  Ruxolitinib Plus Nivolumab in Patients with R/R Hodgkin Lymphoma after Failure of Check-Point Inhibitors: Preliminary Report on Safety and Efficacy , 2021, Blood.

[4]  A. Zannettino,et al.  Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues. , 2021, Cell Reports.

[5]  Michael R Hamblin,et al.  Immune checkpoint inhibition in classical hodgkin lymphoma , 2021, Expert review of anticancer therapy.

[6]  A. McGuigan,et al.  Gelatin‐Hyaluronan Click‐Crosslinked Cryogels Elucidate Human Macrophage Invasion Behavior , 2021, Advanced Functional Materials.

[7]  L. Xue,et al.  Tumor-associated macrophages: potential therapeutic strategies and future prospects in cancer , 2021, Journal for ImmunoTherapy of Cancer.

[8]  Emre Delen,et al.  The Dose Dependent Effects of Ruxolitinib on the Invasion and Tumorigenesis in Gliomas Cells via Inhibition of Interferon Gamma-Depended JAK/STAT Signaling Pathway , 2020, Journal of Korean Neurosurgical Society.

[9]  Krasimira T. Petrova,et al.  Challenges in Matrix Metalloproteinases Inhibition , 2020, Biomolecules.

[10]  M. Shoichet,et al.  Designer Biomaterials to Model Cancer Cell Invasion In Vitro: Predictive Tools or Just Pretty Pictures? , 2020, Advanced Functional Materials.

[11]  Allen W. Zhang,et al.  Single cell transcriptome analysis reveals disease-defining T cell subsets in the tumor microenvironment of classic Hodgkin lymphoma. , 2019, Cancer discovery.

[12]  Julia C. Engelmann,et al.  High CD206 levels in Hodgkin lymphoma‐educated macrophages are linked to matrix‐remodeling and lymphoma dissemination , 2019, Molecular oncology.

[13]  G. Fields.  The Rebirth of Matrix Metalloproteinase Inhibitors: Moving Beyond the Dogma , 2019, Cells.

[14]  Gary D Bader,et al.  Benchmarking to the Gold Standard: Hyaluronan‐Oxime Hydrogels Recapitulate Xenograft Models with In Vitro Breast Cancer Spheroid Culture , 2019, Advanced materials.

[15]  K. Sakamoto,et al.  Ruxolitinib shows activity against Hodgkin lymphoma but not primary mediastinal large B-cell lymphoma , 2019, BMC Cancer.

[16]  M. Farrar,et al.  JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors , 2019, Proceedings of the National Academy of Sciences.

[17]  W. Sommergruber,et al.  3D-3-culture: A tool to unveil macrophage plasticity in the tumour microenvironment. , 2018, Biomaterials.

[18]  H. Drexler,et al.  Hodgkin lymphoma cell lines: to separate the wheat from the chaff , 2018, Biological chemistry.

[19]  Yu Zhou,et al.  An Image Analysis Resource for Cancer Research: PIIP-Pathology Image Informatics Platform for Visualization, Analysis, and Management. , 2017, Cancer research.

[20]  M. Shoichet,et al.  Independently Tuning the Biochemical and Mechanical Properties of 3D Hyaluronan-Based Hydrogels with Oxime and Diels-Alder Chemistry to Culture Breast Cancer Spheroids. , 2017, Biomacromolecules.

[21]  R. Gascoyne,et al.  Prognostic Model to Predict Post-Autologous Stem-Cell Transplantation Outcomes in Classical Hodgkin Lymphoma. , 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[22]  Yiping Yang,et al.  Tumor-associated macrophages: implications in cancer immunotherapy. , 2017, Immunotherapy.

[23]  M. Saleem,et al.  Impact by pancreatic stellate cells on epithelial-mesenchymal transition and pancreatic cancer cell invasion: Adding a third dimension in vitro. , 2016, Experimental cell research.

[24]  N. Papo,et al.  Matrix metalloproteinase protein inhibitors: highlighting a new beginning for metalloproteinases in medicine , 2016 .

[25]  J. Al-Maghrabi,et al.  High tumour-associated macrophages infiltration is correlated with poor survival outcome in classical Hodgkin’s lymphoma , 2015 .

[26]  H. McKenzie,et al.  How I treat advanced classical Hodgkin lymphoma. , 2015, Blood.

[27]  D. Scott,et al.  The classical Hodgkin lymphoma tumor microenvironment: macrophages and gene expression-based modeling. , 2014, Hematology. American Society of Hematology. Education Program.

[28]  C. Simmler,et al.  Importance of Purity Evaluation and the Potential of Quantitative 1H NMR as a Purity Assay , 2014, Journal of medicinal chemistry.

[29]  R. Gascoyne,et al.  The tumour microenvironment in B cell lymphomas , 2014, Nature Reviews Cancer.

[30]  Poonam Kothari,et al.  IL-6–Mediated Induction of Matrix Metalloproteinase-9 Is Modulated by JAK-Dependent IL-10 Expression in Macrophages , 2014, The Journal of Immunology.

[31]  C. Lan,et al.  Expression of M2-Polarized Macrophages is Associated with Poor Prognosis for Advanced Epithelial Ovarian Cancer , 2013, Technology in cancer research & treatment.

[32]  Stéphanie Balor,et al.  The Process of Macrophage Migration Promotes Matrix Metalloproteinase-Independent Invasion by Tumor Cells , 2011, The Journal of Immunology.

[33]  E. Morii,et al.  Prognostic implication of types of tumor-associated macrophages in Hodgkin lymphoma , 2011, Virchows Archiv.

[34]  Steven J. M. Jones,et al.  Tumor-associated macrophages and survival in classic Hodgkin's lymphoma. , 2010, The New England journal of medicine.

[35]  F. Gauffre,et al.  Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures , 2009, The Journal of Immunology.

[36]  Y. Chiba,et al.  A novel STAT6 inhibitor AS1517499 ameliorates antigen-induced bronchial hypercontractility in mice. , 2009, American journal of respiratory cell and molecular biology.

[37]  D. Chung,et al.  Endotoxin Contamination in Commercially Available Pokeweed Mitogen Contributes to the Activation of Murine Macrophages and Human Dendritic Cell Maturation , 2006, Clinical and Vaccine Immunology.

[38]  Michael V Sefton,et al.  Endotoxin: the uninvited guest. , 2005, Biomaterials.

[39]  Jyrki Heino,et al.  Integrin-mediated Cell Adhesion to Type I Collagen Fibrils* , 2004, Journal of Biological Chemistry.

[40]  A. Kanık,et al.  Prognostic value of matrix metalloproteinases (MMP‐2 and MMP‐9) in Hodgkin's and non‐Hodgkin's lymphoma , 2004, International journal of clinical practice.

[41]  S. Pileri,et al.  Hodgkin's lymphoma: the pathologist's viewpoint. , 2002, Journal of clinical pathology.

[42]  A. Ruifrok,et al.  Quantification of histochemical staining by color deconvolution. , 2001, Analytical and quantitative cytology and histology.

[43]  A. Delmas,et al.  Identification of by-products from an orthogonal peptide ligation by oxime bonds using mass spectrometry and tandem mass spectrometry. , 2000, Rapid communications in mass spectrometry : RCM.

[44]  Michael C. Ostrowski,et al.  Macrophage Colony-stimulating Factor Promotes Cell Survival through Akt/Protein Kinase B* , 1999, The Journal of Biological Chemistry.

[45]  C. von Kalle,et al.  Preliminary report: growth of Hodgkin's lymphoma derived cells in immune compromised mice. , 1992, Annals of oncology : official journal of the European Society for Medical Oncology.

[46]  K. Alitalo,et al.  Fibronectin is produced by human macrophages , 1980, The Journal of experimental medicine.