Versatility of the Biginelli reaction: Synthesis of new biphenyl dihydropyrimidin-2-thiones using different ketones as building blocks

[1]  D. Kawano,et al.  Effect of N-1 arylation of monastrol on kinesin Eg5 inhibition in glioma cell lines. , 2018, MedChemComm.

[2]  D. Kawano,et al.  Thioureas as Building Blocks for the Generation of Heterocycles and Compounds with Pharmacological Activity: An Overview , 2017 .

[3]  Kapil Kumar,et al.  Recent synthetic and medicinal perspectives of dihydropyrimidinones: A review , 2017, European Journal of Medicinal Chemistry.

[4]  Arindam Mukhopadhyay,et al.  Biginelli reaction: an overview , 2016 .

[5]  A. F. Shojaei,et al.  PEG-SANM nanocomposite: a new catalytic application towards clean and highly efficient Biginelli-like reaction under solvent-free conditions , 2016 .

[6]  A. Tolmachev,et al.  Protecting Group Free Synthesis of Carboxyl‐substituted Dihydropyrimidines Through Biginelli Reaction , 2013 .

[7]  U. Rashid,et al.  Bioisosteric approach in designing new monastrol derivatives: an investigation on their ADMET prediction using in silico derived parameters. , 2013, Journal of molecular graphics & modelling.

[8]  S. Chakraborty,et al.  Regioselective N1-alkylation of 3,4-dihydropyrimidine-2(1H)-ones: screening of their biological activities against Ca(2+)-ATPase. , 2012, European journal of medicinal chemistry.

[9]  Matthew E Welsch,et al.  Privileged scaffolds for library design and drug discovery. , 2010, Current opinion in chemical biology.

[10]  D. Arora,et al.  N1-Alkylated 3,4-dihydropyrimidine-2(1H)-ones: Convenient one-pot selective synthesis and evaluation of their calcium channel blocking activity. , 2009, European journal of medicinal chemistry.

[11]  B. Testa,et al.  The Biochemistry of Drug Metabolism – An Introduction , 2007, Chemistry & biodiversity.

[12]  Shenlin Huang,et al.  Highly Chemoselective Multicomponent Biginelli‐Type Condensations of Cycloalkanones, Urea or Thiourea and Aldehydes , 2005 .