Creation of Nanoparticle–Nanotube Conjugates for Life-Science Application Using Gas–Liquid Interfacial Plasmas

Gold nanoparticles (AuNPs) conjugated with carbon nanotubes (CNTs) and/or biomolecules such as DNA are synthesized by a novel plasma technique combined with the introduction of ionic liquids or aqueous solutions for application to life sciences. We successfully generated the gas–liquid interfacial discharge plasma (GLIDP) using an ionic liquid, in which a large sheath electric field was formed on the ionic liquid and high-energy plasma ion irradiation to the ionic liquid was realized. Using this GLIDP, it is found that the high-energy ion irradiation to the ionic liquid is effective for the synthesis of AuNPs. Furthermore, controlled ion irradiation to the ionic liquid including functional groups can realize distance-controlled synthesis of AuNPs on CNTs by dissociation of the ionic liquid and the functionalization of CNTs by dissociated carboxyl and amino groups. On the other hand, DNA is used as the functional group that connects the AuNPs to the CNTs. Monodispersed and high-density AuNPs are synthesized on CNTs in the same way as the carboxyl and amino groups.

[1]  Qiang Chen,et al.  Synthesis of nano-bio conjugates for drug delivery systems using gas-liquid interfacial discharge plasmas , 2012 .

[2]  Rikizo Hatakeyama,et al.  Rapid synthesis of water-soluble gold nanoparticles with control of size and assembly using gas–liquid interfacial discharge plasma , 2012 .

[3]  Qiang Chen,et al.  Characterization of pulse-driven gas-liquid interfacial discharge plasmas and application to synthesis of gold nanoparticle-DNA encapsulated carbon nanotubes , 2011 .

[4]  R. M. Sankaran,et al.  Direct Writing of Metal Nanoparticles by Localized Plasma Electrochemical Reduction of Metal Cations in Polymer Films , 2011 .

[5]  R. Hatakeyama,et al.  Structural and reactive kinetics in gas–liquid interfacial plasmas , 2011 .

[6]  Qiang Chen,et al.  Effects of ionic liquid electrode on pulse discharge plasmas in the wide range of gas pressures , 2010 .

[7]  T. Kaneko,et al.  Synthesis of monodispersed nanoparticles functionalized carbon nanotubes in plasma-ionic liquid interfacial fields. , 2010, Chemical communications.

[8]  T. Kaneko,et al.  Versatile Control of Carbon Nanotube Semiconducting Properties by DNA Encapsulation Using Electrolyte Plasmas , 2009 .

[9]  T. Kaneko,et al.  Novel Gas-Liquid Interfacial Plasmas for Synthesis of Metal Nanoparticles , 2009 .

[10]  T. Kaneko,et al.  Static gas-liquid interfacial direct current discharge plasmas using ionic liquid cathode , 2009 .

[11]  R. M. Sankaran,et al.  Plasma-liquid electrochemistry: Rapid synthesis of colloidal metal nanoparticles by microplasma reduction of aqueous cations , 2008 .

[12]  O. Takai,et al.  Exotic shapes of gold nanoparticles synthesized using plasma in aqueous solution , 2008 .

[13]  Yongbing Xie,et al.  Stability of Ionic Liquids under the Influence of Glow Discharge Plasmas , 2008 .

[14]  T. Kaneko,et al.  Ion irradiation effects on ionic liquids interfaced with rf discharge plasmas , 2007 .

[15]  D. Fernig,et al.  Determination of size and concentration of gold nanoparticles from UV-vis spectra. , 2007, Analytical chemistry.

[16]  J. Janek,et al.  Employing plasmas as gaseous electrodes at the free surface of ionic liquids: deposition of nanocrystalline silver particles. , 2007, Chemphyschem : a European journal of chemical physics and physical chemistry.

[17]  N. Tanaka,et al.  Sputter deposition onto ionic liquids: Simple and clean synthesis of highly dispersed ultrafine metal nanoparticles , 2006 .

[18]  T. Kaneko,et al.  Atmospheric Pressure Glow-Discharge Plasmas with Gas–Liquid Interface , 2006 .

[19]  T. Kaneko,et al.  Electrically triggered insertion of single-stranded DNA into single-walled carbon nanotubes , 2006 .

[20]  Myoungseok Lee,et al.  Platinum nanoparticles prepared by a plasma-chemical reduction method , 2005 .

[21]  V. Rotello,et al.  Controlled Plasmon Resonance of Gold Nanoparticles Self-Assembled with PAMAM Dendrimers , 2005 .

[22]  M. Prato,et al.  Functionalized carbon nanotubes for plasmid DNA gene delivery. , 2004, Angewandte Chemie.

[23]  Aharon Gedanken,et al.  The Surface Chemistry of Au Colloids and Their Interactions with Functional Amino Acids , 2004 .

[24]  Robin D. Rogers,et al.  Ionic Liquids--Solvents of the Future? , 2003, Science.

[25]  K. R. Seddon,et al.  Ionic liquids: a taste of the future. , 2003, Nature materials.