ATM Engages Autodegradation of the E3 Ubiquitin Ligase COP1 After DNA Damage
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Somasekar Seshagiri | Vishva M Dixit | S. Seshagiri | V. Dixit | D. Dornan | H. Shimizu | Angie S. Mah | Tanay Dudhela | M. Eby | K. O'rourke | David Dornan | Harumi Shimizu | Michael Eby | Angie Mah | Tanay Dudhela | Karen O'rourke | Harumi Shimizu | K. O’Rourke
[1] A. Levine,et al. The P53 pathway: what questions remain to be explored? , 2006, Cell Death and Differentiation.
[2] Y. Shiloh,et al. Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[3] Y. Shiloh. ATM and related protein kinases: safeguarding genome integrity , 2003, Nature Reviews Cancer.
[4] K. Kinzler,et al. Genetic instabilities in human cancers , 1998, Nature.
[5] D. Pinkel,et al. Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability. , 1995, Genes & development.
[6] G. Frantz,et al. COP1, the Negative Regulator of p53, Is Overexpressed in Breast and Ovarian Adenocarcinomas , 2004, Cancer Research.
[7] S. T. Kim,et al. Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members* , 1999, The Journal of Biological Chemistry.
[8] Petra de Graaf,et al. Phosphorylation of Hdmx mediates its Hdm2- and ATM-dependent degradation in response to DNA damage. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[9] Y Taya,et al. DNA damage induces phosphorylation of the amino terminus of p53. , 1997, Genes & development.
[10] M. Kastan,et al. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation , 2003, Nature.
[11] Patrick Dowd,et al. The ubiquitin ligase COP1 is a critical negative regulator of p53 , 2004, Nature.
[12] C. Wolkow,et al. Levels of p53 protein increase with maturation in human hematopoietic cells. , 1991, Cancer research.
[13] Martin Rechsteiner,et al. Recognition of the polyubiquitin proteolytic signal , 2000, The EMBO journal.
[14] S. T. Kim,et al. ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage. , 2001, Genes & development.
[15] D. Meek,et al. Serine 15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2 , 1999, The EMBO journal.
[16] B. Vogelstein,et al. Participation of p53 protein in the cellular response to DNA damage. , 1991, Cancer research.