Pd(0)-Catalyzed Decarboxylative Coupling and Tandem C—H Arylation/Decarboxylation for the Synthesis of Heteroaromatic Biaryls.
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In the presence of carbene complex PAL, the acids (I) and (IV) undergo decarboxylative coupling with aryl bromides as a new and regioselective access to heteroaromatic biaryls like (III) and (V).
[1] H. Lee,et al. Pd(0)-catalyzed decarboxylative coupling and tandem C-H arylation/decarboxylation for the synthesis of heteroaromatic biaryls. , 2012, The Journal of organic chemistry.