NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding

[1]  Y. Reshetnyak,et al.  Polyamines drive myeloid cell survival by buffering intracellular pH to promote immunosuppression in glioblastoma , 2021, Science Advances.

[2]  G. Siuzdak,et al.  Metabolic adaptation to calorie restriction , 2020, Science Signaling.

[3]  Mark A. McCormick,et al.  Life span extension by glucose restriction is abrogated by methionine supplementation: Cross-talk between glucose and methionine and implication of methionine as a key regulator of life span , 2020, Science Advances.

[4]  Yu-Han H. Hsu,et al.  Hepatic NADH reductive stress underlies common variation in metabolic traits , 2020, Nature.

[5]  Mark S. Schmidt,et al.  NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging. , 2020, Molecular cell.

[6]  G. Barish,et al.  Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis , 2019, eLife.

[7]  M. Pagano,et al.  Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism , 2019, Current Biology.

[8]  M. Haigis,et al.  The multifaceted contributions of mitochondria to cellular metabolism , 2018, Nature Cell Biology.

[9]  R. Zechner,et al.  Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis. , 2017, Cell metabolism.

[10]  C. Green,et al.  Mice under Caloric Restriction Self-Impose a Temporal Restriction of Food Intake as Revealed by an Automated Feeder System. , 2017, Cell metabolism.

[11]  M. Lazar,et al.  Circadian time signatures of fitness and disease , 2016, Science.

[12]  E. Gratton,et al.  Spatial dynamics of SIRT1 and the subnuclear distribution of NADH species , 2016, Proceedings of the National Academy of Sciences.

[13]  V. Mootha,et al.  Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio , 2016, Science.

[14]  Peter Fristrup,et al.  Investigating the Sensitivity of NAD+-dependent Sirtuin Deacylation Activities to NADH* , 2016, The Journal of Biological Chemistry.

[15]  J. Rutter,et al.  Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis. , 2015, Cell metabolism.

[16]  M. Scholle,et al.  Discovery of SIRT3 Inhibitors Using SAMDI Mass Spectrometry , 2015, Journal of biomolecular screening.

[17]  J. Baur,et al.  Increasing NAD Synthesis in Muscle via Nicotinamide Phosphoribosyltransferase Is Not Sufficient to Promote Oxidative Metabolism* , 2014, The Journal of Biological Chemistry.

[18]  M. Hughes,et al.  A circadian gene expression atlas in mammals: Implications for biology and medicine , 2014, Proceedings of the National Academy of Sciences.

[19]  L. Rui,et al.  Energy metabolism in the liver. , 2014, Comprehensive Physiology.

[20]  J. Denu,et al.  Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice , 2013, Science.

[21]  F. Vaz,et al.  Acylcarnitines , 2012, Diabetes.

[22]  J. Takahashi,et al.  Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals , 2012, Science.

[23]  A. B. Reddy,et al.  Circadian Clocks in Human Red Blood Cells , 2010, Nature.

[24]  Milan Mrksich,et al.  Peptide Arrays Identify Isoform-Selective Substrates for Profiling Endogenous Lysine Deacetylase Activity , 2010, ACS chemical biology.

[25]  Joseph S. Takahashi,et al.  Disruption of the Clock Components CLOCK and BMAL 1 Leads to Hypoinsulinemia and Diabetes , 2012 .

[26]  R. Garofalo,et al.  SRT1720, SRT2183, SRT1460, and Resveratrol Are Not Direct Activators of SIRT1♦ , 2010, The Journal of Biological Chemistry.

[27]  J. Takahashi,et al.  Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis , 2009, Science.

[28]  P. Sassone-Corsi,et al.  Circadian Control of the NAD+ Salvage Pathway by CLOCK-SIRT1 , 2009, Science.

[29]  Takashi Nakagawa,et al.  SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle , 2009, Cell.

[30]  Qing Xu,et al.  Hepatocyte-specific deletion of SIRT1 alters fatty acid metabolism and results in hepatic steatosis and inflammation. , 2009, Cell metabolism.

[31]  Kai-Florian Storch,et al.  Physiological significance of a peripheral tissue circadian clock , 2008, Proceedings of the National Academy of Sciences.

[32]  Florian Kreppel,et al.  SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation , 2008, Cell.

[33]  Paolo Sassone-Corsi,et al.  The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control , 2008, Cell.

[34]  F. Alt,et al.  Tissue-specific regulation of SIRT1 by calorie restriction. , 2008, Genes & development.

[35]  Elias Chaibub Neto,et al.  Genetic Networks of Liver Metabolism Revealed by Integration of Metabolic and Transcriptional Profiling , 2008, PLoS genetics.

[36]  M. Mrksich.  Mass spectrometry of self-assembled monolayers: a new tool for molecular surface science. , 2008, ACS nano.

[37]  Weimin He,et al.  Nuclear Receptor Expression Links the Circadian Clock to Metabolism , 2006, Cell.

[38]  H. Tissenbaum,et al.  Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO , 2006, Mechanisms of Ageing and Development.

[39]  A. Fukamizu,et al.  Acetylation of Foxo1 alters its DNA-binding ability and sensitivity to phosphorylation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[40]  S. Fields,et al.  Substrate-specific Activation of Sirtuins by Resveratrol* , 2005, Journal of Biological Chemistry.

[41]  Brian C. Smith,et al.  Mechanism of Human SIRT1 Activation by Resveratrol* , 2005, Journal of Biological Chemistry.

[42]  F. Turek,et al.  Deletion of the mammalian circadian clock gene BMAL1/Mop3 alters baseline sleep architecture and the response to sleep deprivation. , 2005, Sleep.

[43]  K. Oishi,et al.  CLOCK is involved in the circadian transactivation of peroxisome-proliferator-activated receptor α (PPARα) in mice , 2005 .

[44]  Wilhelm Haas,et al.  Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1 , 2005, Nature.

[45]  B. Rogina,et al.  Sir2 mediates longevity in the fly through a pathway related to calorie restriction. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[46]  D. Reinberg,et al.  Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. , 2004, Molecular cell.

[47]  Brian C. Smith,et al.  Coenzyme Specificity of Sir2 Protein Deacetylases , 2004, Journal of Biological Chemistry.

[48]  Myriam Gorospe,et al.  Calorie Restriction Promotes Mammalian Cell Survival by Inducing the SIRT1 Deacetylase , 2004, Science.

[49]  Satoko Aratani,et al.  Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[50]  David Millington,et al.  Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance , 2004, Nature Medicine.

[51]  R. Weindruch,et al.  Influence of age and caloric restriction on liver glycolytic enzyme activities and metabolite concentrations in mice , 2003, Experimental Gerontology.

[52]  R. Weindruch,et al.  Caloric restriction increases gluconeogenic and transaminase enzyme activities in mouse liver , 2003, Experimental Gerontology.

[53]  G. Fink,et al.  Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration , 2002, Nature.

[54]  Kai-Florian Storch,et al.  Extensive and divergent circadian gene expression in liver and heart , 2002, Nature.

[55]  R. Weinberg,et al.  hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase , 2001, Cell.

[56]  J. L. Stringer,et al.  In Vivo Role of NAD(P)H:Quinone Oxidoreductase 1 (NQO1) in the Regulation of Intracellular Redox State and Accumulation of Abdominal Adipose Tissue* , 2001, The Journal of Biological Chemistry.

[57]  P. Defossez,et al.  Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. , 2000, Science.

[58]  J. A. Zimmerman,et al.  Methionine restriction increases blood glutathione and longevity in F344 rats , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[59]  J. McGarry,et al.  Cloning, sequencing, and expression of a cDNA encoding rat liver carnitine palmitoyltransferase I. Direct evidence that a single polypeptide is involved in inhibitor interaction and catalytic function. , 1993, The Journal of biological chemistry.

[60]  J. A. Zimmerman,et al.  Low methionine ingestion by rats extends life span. , 1993, The Journal of nutrition.

[61]  C. McMahan,et al.  Dietary restriction alters characteristics of glucose fuel use. , 1992, Journal of gerontology.

[62]  Roberto Refinetti,et al.  The circadian rhythm of body temperature , 1992, Physiology & Behavior.

[63]  M. Litt,et al.  Analysis of pyridine dinucleotides in cultured rat hepatocytes by high-performance liquid chromatography. , 1989, Analytical biochemistry.

[64]  R. Weindruch,et al.  The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. , 1986, The Journal of nutrition.

[65]  H. Sies,et al.  State of oxidation-reduction and state of binding in the cytosolic NADH-system as disclosed by equilibration with extracellular lactate-pyruvate in hemoglobin-free perfused rat liver. , 1972, European journal of biochemistry.

[66]  H. Krebs,et al.  The redox state of free nicotinamide-adenine dinucleotide in the cytoplasm and mitochondria of rat liver. , 1967, The Biochemical journal.

[67]  V. Paetkau,et al.  Paths of carbon in gluconeogenesis and lipogenesis. 3. The role and regulation of mitochondrial processes involved in supplying precursors of phosphoenolpyruvate. , 1966, The Journal of biological chemistry.

[68]  V. Paetkau,et al.  Paths of carbon in gluconeogenesis and lipogenesis: the role of mitochondria in supplying precursors of phosphoenolpyruvate. , 1965, Proceedings of the National Academy of Sciences of the United States of America.

[69]  P. Mclean,et al.  The determination of oxidized and reduced diphosphopyridine nucleotide and triphosphopyridine nucleotide in animal tissues. , 1955, The Biochemical journal.

[70]  Jack A. Taylor,et al.  Supplementary file 1. , 2011 .

[71]  H. Lardy,et al.  Paths of Carbon in Gluconeogenesis and Lipogenesis , 2011 .

[72]  Steven P Gygi,et al.  Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. , 2005, Nature.

[73]  L. Guarente,et al.  Calorie restriction extends yeast life span by lowering the level of NADH. , 2004, Genes & development.

[74]  L. Guarente,et al.  Negative control of p53 by Sir2alpha promotes cell survival under stress. , 2001, Cell.

[75]  W. Wahli,et al.  Peroxisome proliferator-activated receptor alpha mediates the adaptive response to fasting. , 1999, The Journal of clinical investigation.

[76]  H. Krebs,et al.  Generation of extramitochondrial reducing power in gluconeogenesis. , 1967, The Biochemical journal.