Induction and regulation of epithelial-mesenchymal transitions.
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B. Boyer | A. Vallés | N. Edme | Natacha Edme
[1] J. Thiery,et al. Phosphorylation of Tyrosine Residues 31 and 118 on Paxillin Regulates Cell Migration through an Association with Crk in Nbt-II Cells , 2000, The Journal of cell biology.
[2] Francisco Portillo,et al. The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression , 2000, Nature Cell Biology.
[3] A. G. Herreros,et al. The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells , 2000, Nature Cell Biology.
[4] Y. Nishida,et al. Regulation of JNK by Src during Drosophila development. , 2000, Science.
[5] B. Schaffhauser,et al. Epithelial Mesenchymal Transition by C-Fos Estrogen Receptor Activation Involves Nuclear Translocation of β-Catenin and Upregulation of β-Catenin/Lymphoid Enhancer Binding Factor-1 Transcriptional Activity , 2000, The Journal of cell biology.
[6] A. Sonnenberg,et al. Induction of Cell Scattering by Expression of β1 Integrins in β1-Deficient Epithelial Cells Requires Activation of Members of the Rho Family of Gtpases and Downregulation of Cadherin and Catenin Function , 1999, The Journal of cell biology.
[7] S. Hirohashi,et al. Cell motility mediated by rho and rho‐associated protein kinase plays a critical role in intrahepatic metastasis of human hepatocellular carcinoma , 1999, Hepatology.
[8] T. Tsukamoto,et al. Cell-Cell Dissociation upon Epithelial Cell Scattering Requires a Step Mediated by the Proteasome* , 1999, The Journal of Biological Chemistry.
[9] D. Fabbro,et al. Effect of Potent and Selective Inhibitors of the Grb2 SH2 Domain on Cell Motility* , 1999, The Journal of Biological Chemistry.
[10] D. Montell,et al. The genetics of cell migration in Drosophila melanogaster and Caenorhabditis elegans development. , 1999, Development.
[11] J. Chernoff,et al. p21-Activated Kinase 1 (Pak1) Regulates Cell Motility in Mammalian Fibroblasts , 1999, The Journal of cell biology.
[12] H. Ueno,et al. Platelet-derived Growth Factor Activates p38 Mitogen-activated Protein Kinase through a Ras-dependent Pathway That Is Important for Actin Reorganization and Cell Migration* , 1999, The Journal of Biological Chemistry.
[13] J. Guan,et al. Requirement of Phosphatidylinositol 3-Kinase in Focal Adhesion Kinase-promoted Cell Migration* , 1999, The Journal of Biological Chemistry.
[14] K. Kaibuchi,et al. Phosphorylation of Adducin by Rho-Kinase Plays a Crucial Role in Cell Motility , 1999, The Journal of cell biology.
[15] K. Burridge,et al. Bidirectional signaling between the cytoskeleton and integrins. , 1999, Current opinion in cell biology.
[16] B. Vandenbunder,et al. The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering. , 1999, Molecular biology of the cell.
[17] E. Dejana,et al. Regulation of cadherin function by Rho and Rac: modulation by junction maturation and cellular context. , 1999, Molecular biology of the cell.
[18] Frits Michiels,et al. Matrix-dependent Tiam1/Rac Signaling in Epithelial Cells Promotes Either Cell–Cell Adhesion or Cell Migration and Is Regulated by Phosphatidylinositol 3-Kinase , 1998, The Journal of cell biology.
[19] M. Symons,et al. The Transcription Factor AP-1 Is Required for EGF-induced Activation of Rho-like GTPases, Cytoskeletal Rearrangements, Motility, and In Vitro Invasion of A431 Cells , 1998, The Journal of cell biology.
[20] Z. Kam,et al. Morphogenetic effects of neuregulin (neu differentiation factor) in cultured epithelial cells. , 1998, Molecular biology of the cell.
[21] G. Bokoch,et al. The p21Rac/Cdc42-activated kinases (PAKs). , 1998, The international journal of biochemistry & cell biology.
[22] A. Ridley,et al. Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly. , 1998, Molecular biology of the cell.
[23] M. Kohno,et al. Activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway is required for hepatocyte growth factor-induced cell scattering , 1998, Oncogene.
[24] P. Caroni,et al. Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase , 1998, Nature.
[25] B. Vandenbunder,et al. The expression of an Ets1 transcription factor lacking its activation domain decreases uPA proteolytic activity and cell motility, and impairs normal tubulogenesis and cancerous scattering in mammary epithelial cells. , 1998, Journal of cell science.
[26] R. Herrera. Modulation of hepatocyte growth factor-induced scattering of HT29 colon carcinoma cells. Involvement of the MAPK pathway. , 1998, Journal of cell science.
[27] S. M. Sims,et al. Wortmannin Inhibits Spreading and Chemotaxis of Rat Osteoclasts In Vitro , 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[28] Gerhard Christofori,et al. A causal role for E-cadherin in the transition from adenoma to carcinoma , 1998, Nature.
[29] J. Vandekerckhove,et al. A hand across the Golgi , 1998 .
[30] P. Keely,et al. Integrins and GTPases in tumour cell growth, motility and invasion. , 1998, Trends in cell biology.
[31] G. Nemerow,et al. Adenovirus endocytosis via alpha(v) integrins requires phosphoinositide-3-OH kinase. , 1998, Journal of virology.
[32] G. E. Jones,et al. The Rho GTPases in macrophage motility and chemotaxis. , 1998, Cell adhesion and communication.
[33] E. Bongcam-Rudloff,et al. Cell scattering and migration induced by autocrine transforming growth factor alpha in human glioma cells in vitro. , 1997, Cancer research.
[34] C. Der,et al. Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K , 1997, Nature.
[35] John G. Collard,et al. Inhibition of invasion of epithelial cells by Tiam1-Rac signaling. , 1997, Science.
[36] H. Kotani,et al. Regulation of Cell–Cell Adhesion by Rac and Rho Small G Proteins in MDCK Cells , 1997, The Journal of cell biology.
[37] S. Roche,et al. Src and Ras are involved in separate pathways in epithelial cell scattering , 1997, The EMBO journal.
[38] C. Heldin,et al. Involvement of phosphatidylinositide 3'-kinase and Rac in platelet-derived growth factor-induced actin reorganization and chemotaxis. , 1997, Experimental cell research.
[39] A. Hall,et al. The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts , 1997, The Journal of cell biology.
[40] Kenneth M. Yamada,et al. The Zinc-finger Protein Slug Causes Desmosome Dissociation, an Initial and Necessary Step for Growth Factor–induced Epithelial–mesenchymal Transition , 1997 .
[41] B. Vandenbunder,et al. The ETS1 transcription factor is expressed during epithelial-mesenchymal transitions in the chick embryo and is activated in scatter factor-stimulated MDCK epithelial cells. , 1997, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[42] M. Nieto,et al. Slug, a zinc finger gene previously implicated in the early patterning of the mesoderm and the neural crest, is also involved in chick limb development. , 1997, Development.
[43] J. Bos,et al. Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation , 1997, Oncogene.
[44] M. Krasnow,et al. branchless Encodes a Drosophila FGF Homolog That Controls Tracheal Cell Migration and the Pattern of Branching , 1996, Cell.
[45] B. Shilo,et al. Heartless, a Drosophila FGF receptor homolog, is essential for cell migration and establishment of several mesodermal lineages. , 1996, Genes & development.
[46] B. Vandenbunder,et al. Expression of c-ets-1 and uPA genes is associated with mammary epithelial cell tubulogenesis or neoplastic scattering. , 1996, The International journal of developmental biology.
[47] J. Thiery,et al. α2β1 Integrin is Required for the Collagen and FGF-1 Induced Cell Dispersion in a Rat Bladder Carcinoma Cell Line , 1996 .
[48] Yoshiharu Matsuura,et al. Phosphorylation and Activation of Myosin by Rho-associated Kinase (Rho-kinase)* , 1996, The Journal of Biological Chemistry.
[49] A. Ullrich,et al. Motogenic and morphogenic activity of epithelial receptor tyrosine kinases , 1996, The Journal of cell biology.
[50] H. Schwarz,et al. The estrogen-dependent c-JunER protein causes a reversible loss of mammary epithelial cell polarity involving a destabilization of adherens junctions , 1996, The Journal of cell biology.
[51] P. Hawkins,et al. A heterotrimeric GTPase-regulated isoform of PI3K and the regulation of its potential effectors. , 1996, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
[52] W. Birchmeier,et al. Mechanisms Identified in the Transcriptional Control of Epithelial Gene Expression (*) , 1996, The Journal of Biological Chemistry.
[53] M. Barone,et al. Myc but not Fos rescue of PDGF signalling block caused by kinase-inactive Src , 1995, Nature.
[54] M. Resh,et al. p80/85 Cortactin Associates with the Src SH2 Domain and Colocalizes with v-Src in Transformed Cells (*) , 1995, The Journal of Biological Chemistry.
[55] J. Thiery,et al. pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line , 1995, The Journal of cell biology.
[56] Sheila M. Thomas,et al. Specific and redundant roles of Src and Fyn in organizing the cytoskeleton , 1995, Nature.
[57] A. Bardelli,et al. The motogenic and mitogenic responses to HGF are amplified by the Shc adaptor protein. , 1995, Oncogene.
[58] W. Birchmeier,et al. Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[59] T. Kurosaki,et al. Tyrosine Phosphorylation of Shc Is Mediated through Lyn and Syk in B Cell Receptor Signaling (*) , 1995, The Journal of Biological Chemistry.
[60] M. Roussel,et al. DNA synthesis induced by some but not all growth factors requires Src family protein tyrosine kinases , 1995, Molecular and cellular biology.
[61] P. Comoglio,et al. Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cells , 1995, Molecular and cellular biology.
[62] E. Hay. An overview of epithelio-mesenchymal transformation. , 1995, Acta anatomica.
[63] C. Viebahn. Epithelio-mesenchymal transformation during formation of the mesoderm in the mammalian embryo. , 1995, Acta anatomica.
[64] D. Newgreen,et al. Epithelium-mesenchyme transition during neural crest development. , 1995, Acta anatomica.
[65] R. Derynck,et al. TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors , 1994, The Journal of cell biology.
[66] M. Naujokas,et al. Tyrosine 1356 in the carboxyl-terminal tail of the HGF/SF receptor is essential for the transduction of signals for cell motility and morphogenesis. , 1994, The Journal of biological chemistry.
[67] J. Thiery,et al. Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells. , 1994, Molecular biology of the cell.
[68] Y. Yarden,et al. A single autophosphorylation site confers oncogenicity to the Neu/ErbB‐2 receptor and enables coupling to the MAP kinase pathway. , 1994, The EMBO journal.
[69] W. Birchmeier,et al. Cadherin expression in carcinomas: role in the formation of cell junctions and the prevention of invasiveness. , 1994, Biochimica et biophysica acta.
[70] A. Bardelli,et al. A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family , 1994, Cell.
[71] A. Wells,et al. Cell movement elicited by epidermal growth factor receptor requires kinase and autophosphorylation but is separable from mitogenesis , 1994, The Journal of cell biology.
[72] P. Sternberg,et al. Mutations in the Caenorhabditis elegans let‐23 EGFR‐like gene define elements important for cell‐type specificity and function. , 1994, The EMBO journal.
[73] K. Miyazawa,et al. Tyrosine Phosphorylation of β-Catenin and Plakoglobin Enhanced by Hepatocyte Growth Factor and Epidermal Growth Factor in Human Carcinoma Cells , 1994 .
[74] M. Takeichi. Cadherins in cancer: implications for invasion and metastasis. , 1993, Current opinion in cell biology.
[75] R. Pedersen,et al. The role of E-cadherin and integrins in mesoderm differentiation and migration at the mammalian primitive streak. , 1993, Development.
[76] P. Comoglio,et al. Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger. , 1993, The Journal of biological chemistry.
[77] J. Brugge,et al. Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets , 1993, Molecular and cellular biology.
[78] Frans,et al. Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene , 1993, The Journal of cell biology.
[79] H. Schwarz,et al. Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion , 1992, Cell.
[80] T. Pawson,et al. Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[81] Anne J. Ridley,et al. The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors , 1992, Cell.
[82] J. Thiery,et al. E-cadherin expression during the acidic FGF-induced dispersion of a rat bladder carcinoma cell line. , 1992, Experimental cell research.
[83] K. Miyazawa,et al. Hepatocyte growth factor and transforming growth factor-beta stimulate both cell growth and migration of human gastric adenocarcinoma cells. , 1992, Cell structure and function.
[84] Richard O. Hynes,et al. Integrins: Versatility, modulation, and signaling in cell adhesion , 1992, Cell.
[85] B. Westermark,et al. Thyrocyte migration and histiotypic follicle regeneration are promoted by epidermal growth factor in primary culture of thyroid follicles in collagen gel. , 1991, Endocrinology.
[86] J. Parsons,et al. Identification and characterization of a novel cytoskeleton-associated pp60src substrate , 1991, Molecular and cellular biology.
[87] S. Kellie,et al. Cytoskeletal targets for oncogenic tyrosine kinases. , 1991, Journal of cell science.
[88] B. Geiger,et al. Modulation of intercellular adherens-type junctions and tyrosine phosphorylation of their components in RSV-transformed cultured chick lens cells. , 1991, Cell regulation.
[89] J. Thiery,et al. Alternative patterns of mitogenesis and cell scattering induced by acidic FGF as a function of cell density in a rat bladder carcinoma cell line. , 1990, Cell regulation.
[90] J. Jouanneau,et al. Expression of transfected transforming growth factor alpha induces a motile fibroblast-like phenotype with extracellular matrix-degrading potential in a rat bladder carcinoma cell line. , 1990, Cell regulation.
[91] D. Barritault,et al. Acidic fibroblast growth factor is a modulator of epithelial plasticity in a rat bladder carcinoma cell line. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[92] Raymond B. Runyan,et al. Signal transduction of a tissue interaction during embryonic heart development. , 1990, Cell regulation.
[93] H. Emonard,et al. Collagen-mediated dispersion of NBT-II rat bladder carcinoma cells. , 1990, Cancer research.
[94] J. Thiery,et al. Rearrangements of desmosomal and cytoskeletal proteins during the transition from epithelial to fibroblastoid organization in cultured rat bladder carcinoma cells , 1989, The Journal of cell biology.
[95] J. Parsons,et al. Genetics of src: structure and functional organization of a protein tyrosine kinase. , 1989, Current topics in microbiology and immunology.
[96] L. Luttrell,et al. Augmented mitogenic responsiveness to epidermal growth factor in murine fibroblasts that overexpress pp60c-src , 1988, Molecular and cellular biology.
[97] Yann Barrandon,et al. Cell migration is essential for sustained growth of keratinocyte colonies: The roles of transforming growth factor-α and epidermal growth factor , 1987, Cell.
[98] W J Nelson,et al. Nonmitogenic morphoregulatory action of pp60v-src on multicellular epithelial structures , 1987, Molecular and cellular biology.
[99] C. Damsky,et al. Developmentally regulated expression of the cell-cell adhesion glycoprotein cell-CAM 120/80 in peri-implantation mouse embryos and extraembryonic membranes. , 1986, Developmental biology.
[100] J. Blay,et al. Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells , 1985, Journal of cellular physiology.