Lipophilicity of regioisomers: A case study on 3(2H)-pyridazinones
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[1] P Mátyus,et al. Application of neural networks in structure–activity relationships , 1999, Medicinal research reviews.
[2] P Buchwald,et al. Octanol-water partition: searching for predictive models. , 1998, Current medicinal chemistry.
[3] C. Wermuth. Search for new lead compounds: The example of the chemical and pharmacological dissection of aminopyridazines , 1998 .
[4] T. Kappe. Synthesis and chemistry of pyridazines functionalized in position 3 and 5 with heteroatoms , 1998 .
[5] K. Takács-Novák,et al. Lipophilicity of amphoteric molecules expressed by the true partition coefficient , 1995 .
[6] N. Bodor,et al. An extended version of a novel method for the estimation of partition coefficients. , 1992, Journal of pharmaceutical sciences.
[7] K. Takács-Novák,et al. Lipophilicity of antibacterial fluoroquinolones , 1992 .
[8] M. Sato,et al. Synthesis and biological activity of pyridazinooxazines. , 1982, Chemical & pharmaceutical bulletin.
[9] M. Sato. [Pharmacological studies of 4-ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (M73101). (5) Action of M73101 on the central nervous system (author's transl)]. , 1979, Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
[10] Han van de Waterbeemd,et al. Lipophilicity in drug action and toxicology , 1996 .
[11] W. Meylan,et al. Atom/fragment contribution method for estimating octanol-water partition coefficients. , 1995, Journal of pharmaceutical sciences.
[12] John C. Dearden,et al. The Measurement of Partition Coefficients , 1988 .
[13] A. Ghose,et al. Atomic physicochemical parameters for three dimensional structure directed quantitative structure‐activity relationships III: Modeling hydrophobic interactions , 1988 .