Double-stranded RNA as a mediator in sequence-specific genetic silencing and co-suppression.

[1]  Olivier Voinnet,et al.  Systemic signalling in gene silencing , 1997, Nature.

[2]  J. Mol,et al.  Transgene‐mediated suppression of chalcone synthase expression in Petunia hybrida results from an increase in RNA turnover , 1994 .

[3]  A. Fire,et al.  Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans , 1998, Nature.

[4]  D. Baulcombe,et al.  Requirement of sense transcription for homology‐dependent virus resistance and trans‐inactivation , 1997 .

[5]  K. Kemphues,et al.  par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed , 1995, Cell.

[6]  H. L. Sänger,et al.  RNA-directed de novo methylation of genomic sequences in plants , 1994, Cell.

[7]  J. J. English,et al.  The Frequency and Degree of Cosuppression by Sense Chalcone Synthase Transgenes Are Dependent on Transgene Promoter Strength and Are Reduced by Premature Nonsense Codons in the Transgene Coding Sequence. , 1997, The Plant cell.

[8]  A. Fire,et al.  Production of antisense RNA leads to effective and specific inhibition of gene expression in C. elegans muscle. , 1991, Development.

[9]  D. Baulcombe,et al.  A similarity between viral defense and gene silencing in plants. , 1997, Science.

[10]  D. Baulcombe,et al.  Consistent gene silencing in transgenic plants expressing a replicating potato virus X RNA , 1997, The EMBO journal.

[11]  D. Grierson,et al.  Does co-suppression of sense genes in transgenic plants involve antisense RNA? , 1991 .

[12]  M. Montagu,et al.  Post‐transcriptional β‐1,3‐glucanase gene silencing involves increased transcript turnover that is translation‐independent , 1997 .

[13]  W. Stinebring,et al.  Toxic Properties of a Synthetic Double-stranded RNA: Endotoxin-like Properties of Poly I.Poly C, an Interferon Stimulator , 1969, Nature.

[14]  M. Matzke,et al.  How and Why Do Plants Inactivate Homologous (Trans)genes? , 1995, Plant physiology.

[15]  W. Nellen,et al.  What makes an mRNA anti-sense-itive? , 1993, Trends in biochemical sciences.

[16]  C. Proud,et al.  PKR: a new name and new roles. , 1995, Trends in biochemical sciences.

[17]  H. Vaucheret,et al.  Systemic acquired silencing: transgene‐specific post‐transcriptional silencing is transmitted by grafting from silenced stocks to non‐silenced scions , 1997, The EMBO journal.

[18]  M. Mathews Structure, function, and evolution of adenovirus virus-associated RNAs. , 1995, Current topics in microbiology and immunology.

[19]  D J Lipman,et al.  Making (anti)sense of non-coding sequence conservation. , 1997, Nucleic acids research.

[20]  W. J. Lucas,et al.  An RNA-Based Information Superhighway in Plants , 1998, Science.

[21]  M. Van Montagu,et al.  Post-transcriptional cosuppression of beta-1,3-glucanase genes does not affect accumulation of transgene nuclear mRNA. , 1995, The Plant cell.