Dynamics models for identifying the key transmission parameters of the COVID-19 disease

After the analysis and forecast of COVID-19 spreading in China, Italy, and France the WHO has declared the COVID-19 a pandemic. There are around 100 research groups across the world trying to develop a vaccine for this coronavirus. Therefore, the quantitative and qualitative analysis of the COVID–19 pandemic is needed along with the effect of rapid test infection identification on controlling the spread of COVID-19. Mathematical models with computational simulations are the effective tools that help global efforts to estimate key transmission parameters and further improvements for controlling this disease. This is an infectious disease and can be modeled as a system of non-linear differential equations with reaction rates. In this paper, we develop the models for coronavirus disease at different stages with the addition of more parameters due to interactions among the individuals. Then, some key computational simulations and sensitivity analysis are investigated. Further, the local sensitivities for each model state concerning the model parameters are computed using the model reduction techniques: the dynamical models are eventually changed with the change of parameters are represented graphically.

[1]  Yang Liu,et al.  Early dynamics of transmission and control of COVID-19: a mathematical modelling study , 2020, The Lancet Infectious Diseases.

[2]  M. Kochańczyk,et al.  Dynamics of COVID-19 pandemic at constant and time-dependent contact rates , 2020, medRxiv.

[3]  B. Samet,et al.  An analysis for heat equations arises in diffusion process using new Yang‐Abdel‐Aty‐Cattani fractional operator , 2020, Mathematical Methods in the Applied Sciences.

[4]  D. G. Prakasha,et al.  A fractional model for propagation of classical optical solitons by using nonsingular derivative , 2020 .

[5]  Mohd Hafiz Mohd,et al.  Unravelling the myths of R0 in controlling the dynamics of COVID-19 outbreak: A modelling perspective , 2020, Chaos, Solitons & Fractals.

[6]  Jianhong Wu,et al.  An updated estimation of the risk of transmission of the novel coronavirus (2019-nCov) , 2020, Infectious Disease Modelling.

[7]  M. Irfan,et al.  Slow invariant manifold assessments in multi-route reaction mechanism , 2019, Journal of Molecular Liquids.

[8]  Behzad Ghanbari,et al.  A study of behaviour for immune and tumor cells in immunogenetic tumour model with non-singular fractional derivative , 2020 .

[9]  A. Bouchnita,et al.  A multi-scale model quantifies the impact of limited movement of the population and mandatory wearing of face masks in containing the COVID-19 epidemic in Morocco , 2020, Mathematical Modelling of Natural Phenomena.

[11]  J. Hyman,et al.  Real-time forecasts of the 2019-nCoV epidemic in China from February 5th to February 24th, 2020 , 2020, 2002.05069.

[12]  P. Cochat,et al.  Et al , 2008, Archives de pediatrie : organe officiel de la Societe francaise de pediatrie.

[13]  Devendra Kumar,et al.  An Efficient Numerical Method for Fractional SIR Epidemic Model of Infectious Disease by Using Bernstein Wavelets , 2020, Mathematics.

[14]  Muhammad Shahzad,et al.  Modeling multi-route reaction mechanism for surfaces: a mathematical and computational approach , 2020, Applied Nanoscience.

[15]  B. Samet,et al.  A new Rabotnov fractional‐exponential function‐based fractional derivative for diffusion equation under external force , 2020, Mathematical Methods in the Applied Sciences.

[16]  Amit Kumar,et al.  A nonlinear fractional model to describe the population dynamics of two interacting species , 2017 .

[17]  J. Rocklöv,et al.  The reproductive number of COVID-19 is higher compared to SARS coronavirus , 2020, Journal of travel medicine.

[19]  R. Agarwal,et al.  A study of fractional Lotka‐Volterra population model using Haar wavelet and Adams‐Bashforth‐Moulton methods , 2020, Mathematical Methods in the Applied Sciences.

[21]  L. F. Chaves,et al.  COVID-19 basic reproduction number and assessment of initial suppression policies in Costa Rica , 2020, Mathematical Modelling of Natural Phenomena.

[22]  Sarbaz H. A. Khoshnaw,et al.  Model reductions in biochemical reaction networks , 2015 .

[23]  Ali Akgül,et al.  Mathematical Model for the Ebola Virus Disease , 2018, Journal of Advanced Physics.

[24]  P. Klepac,et al.  Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts , 2020, The Lancet Global Health.

[25]  Sarbaz H. A. Khoshnaw,et al.  A mathematical modelling approach for childhood vaccination with some computational simulations , 2019 .

[26]  Sarbaz H. A. Khoshnaw,et al.  Mathematical modelling for coronavirus disease (COVID-19) in predicting future behaviours and sensitivity analysis , 2020, Mathematical Modelling of Natural Phenomena.

[28]  Sergei Petrovskii,et al.  On a quarantine model of coronavirus infection and data analysis , 2020, Mathematical Modelling of Natural Phenomena.

[29]  Jianhong Wu,et al.  Estimation of the Transmission Risk of the 2019-nCoV and Its Implication for Public Health Interventions , 2020, Journal of clinical medicine.

[30]  B. Samet,et al.  Chaotic behaviour of fractional predator-prey dynamical system , 2020 .

[31]  Michael Y. Li,et al.  Why is it difficult to accurately predict the COVID-19 epidemic? , 2020, Infectious Disease Modelling.

[32]  Utkucan Şahin,et al.  Forecasting the cumulative number of confirmed cases of COVID-19 in Italy, UK and USA using fractional nonlinear grey Bernoulli model , 2020, Chaos, Solitons & Fractals.

[33]  Faisal Sultan,et al.  A quantitative and qualitative analysis of the COVID–19 pandemic model , 2020, Chaos, Solitons & Fractals.

[34]  Sarbaz H. A. Khoshnaw,et al.  REDUCTION OF A KINETIC MODEL OF ACTIVE EXPORT OF IMPORTINS , 2015 .

[35]  David N. Fisman,et al.  Mathematical modelling of COVID-19 transmission and mitigation strategies in the population of Ontario, Canada , 2020, Canadian Medical Association Journal.

[36]  Devendra Kumar,et al.  An efficient numerical scheme for fractional model of HIV-1 infection of CD4+ T-cells with the effect of antiviral drug therapy , 2020 .

[37]  Vineet K. Srivastava,et al.  Numerical approximation for HIV infection of CD4+ T cells mathematical model , 2014 .

[38]  P. Klepac,et al.  Early dynamics of transmission and control of COVID-19: a mathematical modelling study , 2020, The Lancet Infectious Diseases.

[39]  Zafer Cakir,et al.  A Mathematical Modelling Approach in the Spread of the Novel 2019 Coronavirus SARS-CoV-2 (COVID-19) Pandemic , 2020, Electronic Journal of General Medicine.

[40]  M. Jleli,et al.  A fractional derivative with two singular kernels and application to a heat conduction problem , 2020 .