Joint kinematic calculation based on clinical direct kinematic versus inverse kinematic gait models.

Most clinical gait laboratories use the conventional gait analysis model. This model uses a computational method called Direct Kinematics (DK) to calculate joint kinematics. In contrast, musculoskeletal modelling approaches use Inverse Kinematics (IK) to obtain joint angles. IK allows additional analysis (e.g. muscle-tendon length estimates), which may provide valuable information for clinical decision-making in people with movement disorders. The twofold aims of the current study were: (1) to compare joint kinematics obtained by a clinical DK model (Vicon Plug-in-Gait) with those produced by a widely used IK model (available with the OpenSim distribution), and (2) to evaluate the difference in joint kinematics that can be solely attributed to the different computational methods (DK versus IK), anatomical models and marker sets by using MRI based models. Eight children with cerebral palsy were recruited and presented for gait and MRI data collection sessions. Differences in joint kinematics up to 13° were found between the Plug-in-Gait and the gait 2392 OpenSim model. The majority of these differences (94.4%) were attributed to differences in the anatomical models, which included different anatomical segment frames and joint constraints. Different computational methods (DK versus IK) were responsible for only 2.7% of the differences. We recommend using the same anatomical model for kinematic and musculoskeletal analysis to ensure consistency between the obtained joint angles and musculoskeletal estimates.

[1]  Katherine M Steele,et al.  Can Strength Training Predictably Improve Gait Kinematics? A Pilot Study on the Effects of Hip and Knee Extensor Strengthening on Lower-Extremity Alignment in Cerebral Palsy , 2010, Physical Therapy.

[2]  James J Carollo,et al.  The role of gait analysis in treating gait abnormalities in cerebral palsy. , 2010, The Orthopedic clinics of North America.

[3]  Andrea R. Seisler,et al.  Normative Three-Dimensional Patellofemoral and Tibiofemoral Kinematics: A Dynamic, in Vivo Study , 2007, IEEE Transactions on Biomedical Engineering.

[4]  Jeffrey A Reinbolt,et al.  Crouched posture maximizes ground reaction forces generated by muscles. , 2012, Gait & posture.

[5]  F. Zajac,et al.  A planar model of the knee joint to characterize the knee extensor mechanism. , 1989, Journal of biomechanics.

[6]  David G. Lloyd,et al.  Estimation of the hip joint centre in human motion analysis: a systematic review. , 2015, Clinical biomechanics.

[7]  Nicola Hagemeister,et al.  Soft tissue artifact compensation in knee kinematics by multi-body optimization: Performance of subject-specific knee joint models. , 2015, Journal of biomechanics.

[8]  David G Lloyd,et al.  Repeatability of gait data using a functional hip joint centre and a mean helical knee axis. , 2003, Journal of biomechanics.

[9]  K. Manal,et al.  Comparison of surface mounted markers and attachment methods in estimating tibial rotations during walking: an in vivo study. , 2000, Gait & posture.

[10]  Kaat Desloovere,et al.  The relation between spasticity and muscle behavior during the swing phase of gait in children with cerebral palsy. , 2014, Research in developmental disabilities.

[11]  Thomas D. Collins,et al.  A six degrees-of-freedom marker set for gait analysis: repeatability and comparison with a modified Helen Hayes set. , 2009, Gait & posture.

[12]  Paul Ornetti,et al.  Cross-Talk Correction Method for Knee Kinematics in Gait Analysis Using Principal Component Analysis (PCA): A New Proposal , 2014, PloS one.

[13]  Ulrich Glitsch,et al.  Loads in the hip joint during physically demanding occupational tasks: A motion analysis study. , 2015, Journal of biomechanics.

[14]  I Söderkvist,et al.  Determining the movements of the skeleton using well-configured markers. , 1993, Journal of biomechanics.

[15]  Nadia Magnenat-Thalmann,et al.  MRI-based assessment of hip joint translations. , 2009, Journal of biomechanics.

[16]  Marco Viceconti,et al.  Virtual palpation of skeletal landmarks with multimodal display interfaces , 2007, Medical informatics and the Internet in medicine.

[17]  Scott Tashman,et al.  The inaccuracy of surface-measured model-derived tibiofemoral kinematics. , 2012, Journal of biomechanics.

[18]  T. Theologis,et al.  Prediction of the hip joint centre in adults, children, and patients with cerebral palsy based on magnetic resonance imaging. , 2007, Journal of biomechanics.

[19]  Caroline Stewart,et al.  The effects of surgical lengthening of hamstring muscles in children with cerebral palsy--the consequences of pre-operative muscle length measurement. , 2014, Gait & posture.

[20]  Ansgar Schwirtz,et al.  Reliability and accuracy in three-dimensional gait analysis: a comparison of two lower body protocols. , 2013, Journal of applied biomechanics.

[21]  M. Damsgaard,et al.  Kinematic analysis of over-determinate biomechanical systems , 2009, Computer methods in biomechanics and biomedical engineering.

[22]  F.E. Zajac,et al.  An interactive graphics-based model of the lower extremity to study orthopaedic surgical procedures , 1990, IEEE Transactions on Biomedical Engineering.

[23]  Alberto Leardini,et al.  Quantitative comparison of five current protocols in gait analysis. , 2008, Gait & posture.

[24]  Paul Suetens,et al.  Calculating gait kinematics using MR-based kinematic models. , 2011, Gait & posture.

[25]  J J O'Connor,et al.  Bone position estimation from skin marker co-ordinates using global optimisation with joint constraints. , 1999, Journal of biomechanics.

[26]  W C H Parr,et al.  Calculating the axes of rotation for the subtalar and talocrural joints using 3D bone reconstructions. , 2012, Journal of biomechanics.

[27]  Sonia Duprey,et al.  Influence of joint constraints on lower limb kinematics estimation from skin markers using global optimization. , 2010, Journal of biomechanics.

[28]  Michael H Schwartz,et al.  The effect of walking speed on the gait of typically developing children. , 2008, Journal of biomechanics.

[29]  Michael Damsgaard,et al.  Analysis of musculoskeletal systems in the AnyBody Modeling System , 2006, Simul. Model. Pract. Theory.

[30]  Jay Dicharry,et al.  Changes in hip joint muscle-tendon lengths with mode of locomotion. , 2010, Gait & posture.

[31]  Anthony G Schache,et al.  Defining the knee joint flexion-extension axis for purposes of quantitative gait analysis: an evaluation of methods. , 2006, Gait & posture.

[32]  Edgar Erdfelder,et al.  G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences , 2007, Behavior research methods.

[33]  R. B. Davis,et al.  A gait analysis data collection and reduction technique , 1991 .

[34]  B. Fregly,et al.  A solidification procedure to facilitate kinematic analyses based on video system data. , 1995, Journal of biomechanics.

[35]  Nicola Sancisi,et al.  A New Kinematic Model of the Passive Motion of the Knee Inclusive of the Patella , 2011 .

[36]  M P Kadaba,et al.  Measurement of lower extremity kinematics during level walking , 1990, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[37]  J. Reinbolt,et al.  Elevated gastrocnemius forces compensate for decreased hamstrings forces during the weight-acceptance phase of single-leg jump landing: implications for anterior cruciate ligament injury risk. , 2014, Journal of biomechanics.

[38]  M Damsgaard,et al.  Surface marker cluster translation, rotation, scaling and deformation: Their contribution to soft tissue artefact and impact on knee joint kinematics. , 2015, Journal of biomechanics.

[39]  Pam Thomason,et al.  Single Event Multilevel Surgery in children with bilateral spastic cerebral palsy: a 5 year prospective cohort study. , 2013, Gait & posture.

[40]  Jan Andrysek,et al.  Test-retest reliability of discrete gait parameters in children with cerebral palsy. , 2010, Archives of physical medicine and rehabilitation.

[41]  Volker Dürr,et al.  A posture optimization algorithm for model-based motion capture of movement sequences , 2004, Journal of Neuroscience Methods.

[42]  Marco Viceconti,et al.  Are Subject-Specific Musculoskeletal Models Robust to the Uncertainties in Parameter Identification? , 2014, PloS one.

[43]  Adam Rozumalski,et al.  The gait profile score and movement analysis profile. , 2009, Gait & posture.

[44]  Ayman Habib,et al.  OpenSim: Open-Source Software to Create and Analyze Dynamic Simulations of Movement , 2007, IEEE Transactions on Biomedical Engineering.

[45]  I. Charlton,et al.  Repeatability of an optimised lower body model. , 2004, Gait & posture.

[46]  Dan K Ramsey,et al.  Effect of skin movement artifact on knee kinematics during gait and cutting motions measured in vivo. , 2005, Gait & posture.

[47]  Vladimir M. Zatsiorsky Kinematics of human motion , 1998 .

[48]  Hartmut Witte,et al.  ISB recommendation on definitions of joint coordinate system of various joints for the reporting of human joint motion--part I: ankle, hip, and spine. International Society of Biomechanics. , 2002, Journal of biomechanics.

[49]  Jaco F Schutte,et al.  Determination of patient-specific multi-joint kinematic models through two-level optimization. , 2005, Journal of biomechanics.

[50]  S. Delp,et al.  Accuracy of muscle moment arms estimated from MRI-based musculoskeletal models of the lower extremity. , 2000, Computer aided surgery : official journal of the International Society for Computer Aided Surgery.

[51]  Sattar Alshryda,et al.  Development and Reliability of a System to Classify Gross Motor Function in Children with Cerebral Palsy , 2014 .

[52]  S. Piazza,et al.  Measurement of the screw-home motion of the knee is sensitive to errors in axis alignment. , 2000, Journal of biomechanics.

[53]  Nicola Sancisi,et al.  Validation of a multi-body optimization with knee kinematic models including ligament constraints. , 2015, Journal of biomechanics.

[54]  Monica Reggiani,et al.  Estimation of musculotendon parameters for scaled and subject specific musculoskeletal models using an optimization technique. , 2016, Journal of biomechanics.

[55]  E S Grood,et al.  A joint coordinate system for the clinical description of three-dimensional motions: application to the knee. , 1983, Journal of biomechanical engineering.

[56]  James J Carollo,et al.  Effectiveness of Instrumented Gait Analysis in Children With Cerebral Palsy - Comparison of Outcomes , 2006, Journal of pediatric orthopedics.

[57]  A. Cappozzo,et al.  Human movement analysis using stereophotogrammetry. Part 3. Soft tissue artifact assessment and compensation. , 2005, Gait & posture.

[58]  J. Gage Gait analysis. An essential tool in the treatment of cerebral palsy. , 1993, Clinical orthopaedics and related research.

[59]  R. Palisano,et al.  Development and reliability of a system to classify gross motor function in children with cerebral palsy , 1997, Developmental medicine and child neurology.

[60]  Neil Ferreira Novo,et al.  Are the recommendations from three-dimensional gait analysis associated with better postoperative outcomes in patients with cerebral palsy? , 2008, Gait & posture.

[61]  J. Vanrenterghem,et al.  Impact of knee modeling approach on indicators and classification of anterior cruciate ligament injury risk. , 2014, Medicine and science in sports and exercise.

[62]  R. Tugui,et al.  Cerebral palsy gait, clinical importance. , 2013, Maedica.

[63]  L. Duffell,et al.  Comparison of kinematic and kinetic parameters calculated using a cluster-based model and Vicon’s plug-in gait , 2014, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[64]  Michael Damsgaard,et al.  Do kinematic models reduce the effects of soft tissue artefacts in skin marker-based motion analysis? An in vivo study of knee kinematics. , 2010, Journal of biomechanics.

[65]  Ilse Jonkers,et al.  Arm swing in human walking: what is their drive? , 2014, Gait & posture.

[66]  C. Yeow,et al.  Contributions of the soleus and gastrocnemius muscles to the anterior cruciate ligament loading during single-leg landing. , 2013, Journal of biomechanics.

[67]  A. Cappozzo,et al.  Human movement analysis using stereophotogrammetry. Part 1: theoretical background. , 2005, Gait & posture.

[68]  A. Cappozzo,et al.  Human movement analysis using stereophotogrammetry. Part 2: instrumental errors. , 2004, Gait & posture.

[69]  Ingrid Skaaret,et al.  Gait improvement surgery in ambulatory children with diplegic cerebral palsy , 2015, Acta orthopaedica.

[70]  Bryan Buchholz,et al.  ISB recommendation on definitions of joint coordinate systems of various joints for the reporting of human joint motion--Part II: shoulder, elbow, wrist and hand. , 2005, Journal of biomechanics.

[71]  Liu Yang,et al.  Identifying the Functional Flexion-extension Axis of the Knee: An In-Vivo Kinematics Study , 2015, PloS one.

[72]  L Modenese,et al.  Application of a falsification strategy to a musculoskeletal model of the lower limb and accuracy of the predicted hip contact force vector. , 2013, Journal of biomechanics.

[73]  Richard Baker,et al.  The comparison of normative reference data from different gait analysis services. , 2014, Gait & posture.

[74]  Guoan Li,et al.  Six DOF in vivo kinematics of the ankle joint complex: Application of a combined dual‐orthogonal fluoroscopic and magnetic resonance imaging technique , 2006, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[75]  M. Morris,et al.  The reliability of three-dimensional kinematic gait measurements: a systematic review. , 2009, Gait & posture.

[76]  Angelo Cappello,et al.  Double calibration vs. global optimisation: performance and effectiveness for clinical application. , 2006, Gait & posture.

[77]  William R Taylor,et al.  Anterior Cruciate Ligament–Deficient Patients With Passive Knee Joint Laxity Have a Decreased Range of Anterior-Posterior Motion During Active Movements , 2013, The American journal of sports medicine.

[78]  Ling Wang,et al.  Effect of component mal‐rotation on knee loading in total knee arthroplasty using multi‐body dynamics modeling under a simulated walking gait , 2015, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[79]  Christopher P Carty,et al.  Muscle contributions to recovery from forward loss of balance by stepping. , 2014, Journal of biomechanics.