Optical properties of fat emulsions.

We present measurements of the optical properties of six different fat emulsions from three different brands, Clinoleic, Lipovenoes and Intralipid, with fat concentrations from 10% to 30%. The scattering coefficient, the reduced scattering coefficient, and the phase function of each sample are measured for wavelengths between 350 nm and 900 nm. A method for the calculation of the particle size distribution of these fat emulsions is introduced. With the particle size distribution the optical properties of the fat emulsions are obtained with Mie theory. Simple equations for the calculation of the absorption coefficient, the scattering coefficient, the reduced scattering coefficient, the g factor, and the phase function of all measured samples are presented.

[1]  G. Mie Beiträge zur Optik trüber Medien, speziell kolloidaler Metallösungen , 1908 .

[2]  M S Patterson,et al.  Total attenuation coefficients and scattering phase functions of tissues and phantom materials at 633 nm. , 1987, Medical physics.

[3]  I. Driver,et al.  The optical properties of aqueous suspensions of Intralipid, a fat emulsion , 1989 .

[4]  W. M. Haynes CRC Handbook of Chemistry and Physics , 1990 .

[5]  H. J. van Staveren,et al.  Light scattering in Intralipid-10% in the wavelength range of 400-1100 nm. , 1991, Applied optics.

[6]  S L Jacques,et al.  Optical properties of intralipid: A phantom medium for light propagation studies , 1992, Lasers in surgery and medicine.

[7]  D. Lide Handbook of Chemistry and Physics , 1992 .

[8]  M. H. Koelink,et al.  Reduced light-scattering properties for mixtures of spherical particles: a simple approximation derived from Mie calculations. , 1992, Applied optics.

[9]  R. Steiner,et al.  Spatially resolved absolute diffuse reflectance measurements for noninvasive determination of the optical scattering and absorption coefficients of biological tissue. , 1996, Applied optics.

[10]  M. Patterson,et al.  Improved solutions of the steady-state and the time-resolved diffusion equations for reflectance from a semi-infinite turbid medium. , 1997, Journal of the Optical Society of America. A, Optics, image science, and vision.

[11]  E. Fry,et al.  Absorption spectrum (380-700 nm) of pure water. II. Integrating cavity measurements. , 1997, Applied optics.

[12]  J. L'Huillier,et al.  Measurements of Scattering Effects Within Tissue-like Media at Two Wavelengths of 632.8 nm and 680 nm , 1999, Lasers in Medical Science.

[13]  J. S. Dam,et al.  Quantifying the absorption and reduced scattering coefficients of tissuelike turbid media over a broad spectral range with noncontact Fourier-transform hyperspectral imaging. , 2000, Applied optics.

[14]  R Hibst,et al.  Influence of the phase function on determination of the optical properties of biological tissue by spatially resolved reflectance. , 2001, Optics letters.

[15]  Fabrizio Martelli,et al.  Measurements of optical properties of high-density media. , 2003, Applied optics.

[16]  Optical properties of high-density dispersions of particles: application to intralipid solutions. , 2003, Applied optics.

[17]  S. Psycharakis,et al.  Optical properties and chromophore concentration measurements in tissue-like phantoms , 2005 .

[18]  Alwin Kienle,et al.  Phase function measurements on nonspherical scatterers using a two-axis goniometer. , 2006, Journal of biomedical optics.

[19]  S. Boll,et al.  Measurement of the phase function of phantom medias with a two axis goniometer , 2007, European Conference on Biomedical Optics.

[20]  Alwin Kienle,et al.  Determination of the optical properties of turbid media by measurement of the spatially resolved reflectance , 2007, European Conference on Biomedical Optics.

[21]  Norman S. Williams,et al.  Standardization of intralipid for light scattering in clinical photodynamic therapy , 2007, Lasers in Medical Science.

[22]  Fabrizio Martelli,et al.  Calibration of scattering and absorption properties of a liquid diffusive medium at NIR wavelengths. CW method. , 2007, Optics express.

[23]  J. R. Cooper,et al.  The International Association for the Properties of Water and Steam , 2008 .