Intracranial pressure oscillations (B-waves) caused by oscillations in cerebrovascular volume

SummaryIn experiments during stepwise increases in intracranial pressure, B-waves could be provoked synchronously with pial vascular diameter oscillations. The vascular oscillations are known to be a sign of myogenic cerebrovascular regulation. An increase in their amplitude indicates vessel wall relaxation and impending failure of myogenic autoregulation. Therefore, vascular oscillations provoked during intracranial hypertension can be ascribed to a fall in transmural pressure and vessel wall tension. The resulting oscillations in the cerebral blood volume are reflected by ICP oscillations and lead to synchronous variation in ICP, the so-called “B-waves” with a frequency of 0.5 to 2 per minute.

[1]  W. Bayliss.  On the local reactions of the arterial wall to changes of internal pressure , 1902, The Journal of physiology.

[2]  C. Jørgensen,et al.  Survival and function of auto- and homografts of adenohypophysial tissue in the toad, bufo bufo L. , 1956, Acta physiologica Scandinavica.

[3]  N. Lundberg,et al.  Continuous recording and control of ventricular fluid pressure in neurosurgical practice. , 1962, Acta psychiatrica Scandinavica. Supplementum.

[4]  B. Folkow,et al.  DESCRIPTION OF THE MYOGENIC HYPOTHESIS. , 1964, Circulation research.

[5]  G. Biamino,et al.  Synchronization and conduction of excitation in the rat aorta. , 1969, The American journal of physiology.

[6]  B. Johansson.  Determinants of vascular reactivity. , 1974, Federation proceedings.

[7]  L. Symon,et al.  Some Aspects of Cerebrovascular Resistance in Raised Intracranial Pressure: An Experimental Study , 1975 .

[8]  H. Koepchen,et al.  Membrane Potential and Relaxation in Vascular Smooth Muscle , 1978 .

[9]  Ludwig Michael Auer,et al.  The Pathogenesis of Hypertensive Encephalopathy , 1978, Acta Neurochirurgica.

[10]  S. E. Børgesen,et al.  Etiology of B-Waves , 1980 .

[11]  B. Gallhofer,et al.  Rhythmic activity of cat pial vessels in vivo. , 1981, European neurology.

[12]  B. Johansson,et al.  Sympathoadrenergic Modulation of Cerebral Blood Volume During Increased ICP , 1983 .

[13]  CSF Pulse Wave, ICP, and Autoregulation , 1983 .

[14]  H. Portnoy,et al.  Starling Resistor as a Model of the Cerebrovascular Bed , 1983 .

[15]  L. Auer.  A method for continuous monitoring of pial vessel diameter changes and its value for dynamic studies of the regulation of cerebral circulation. A preliminary report , 1978, Pflügers Archiv.