Antithrombotic activity of HY023016, a novel Dabigatran prodrug evaluated in animal thrombosis models.
暂无分享,去创建一个
Yi Zhou | Yun-Gen Xu | Guoqing Gong | Meiling Jiang | Wenhui Yang | Yun-Zhan Li | Xin-Hui Wang | Guang-wei He | Xiao-Zhi Yang
[1] Yun-Gen Xu,et al. Synthesis and antithrombotic evaluation of novel dabigatran prodrugs containing a cleavable moiety with anti-platelet activity. , 2012, European journal of medicinal chemistry.
[2] B. Eriksson,et al. Evaluation of the acute coronary syndrome safety profile of dabigatran etexilate in patients undergoing major orthopedic surgery: findings from four Phase 3 trials. , 2012, Thrombosis research.
[3] E. D. Candia,et al. Mechanisms of platelet activation by thrombin: A short history , 2012 .
[4] T. Mavrakanas,et al. The potential role of new oral anticoagulants in the prevention and treatment of thromboembolism. , 2011, Pharmacology & therapeutics.
[5] S. Yusuf,et al. Newly identified events in the RE-LY trial. , 2010, The New England journal of medicine.
[6] A. Siegbahn,et al. The influence of direct thrombin inhibitors on the formation of platelet-leukocyte aggregates and tissue factor expression. , 2010, Thrombosis research.
[7] A. Clemens,et al. Dabigatran: an oral novel potent reversible nonpeptide inhibitor of thrombin. , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[8] S. Goldhaber,et al. Dabigatran versus warfarin in the treatment of acute venous thromboembolism. , 2009, The New England journal of medicine.
[9] A. Lau,et al. Antiplatelet and anticoagulant effects of Panax notoginseng: comparison of raw and steamed Panax notoginseng with Panax ginseng and Panax quinquefolium. , 2009, Journal of ethnopharmacology.
[10] V. Laux,et al. Direct inhibitors of coagulation proteins – the end of the heparin and low-molecular-weight heparin era for anticoagulant therapy? , 2009, Thrombosis and Haemostasis.
[11] H. Bounameaux. The novel anticoagulants: entering a new era. , 2009, Swiss medical weekly.
[12] M. Franchini,et al. Venous and arterial thrombosis: different sides of the same coin? , 2008, European journal of internal medicine.
[13] P. Lam,et al. Apixaban, an oral, direct and highly selective factor Xa inhibitor: in vitro, antithrombotic and antihemostatic studies , 2008, Journal of thrombosis and haemostasis : JTH.
[14] S. Frostick,et al. Oral dabigatran etexilate vs. subcutaneous enoxaparin for the prevention of venous thromboembolism after total knee replacement: the RE‐MODEL randomized trial , 2007, Journal of thrombosis and haemostasis : JTH.
[15] M. Ezekowitz,et al. Dabigatran with or without concomitant aspirin compared with warfarin alone in patients with nonvalvular atrial fibrillation (PETRO Study). , 2007, The American journal of cardiology.
[16] E. Liu,et al. Antithrombotic and hemostatic effects of a small molecule factor XIa inhibitor in rats. , 2007, European journal of pharmacology.
[17] J. Stassen,et al. Effects of the direct thrombin inhibitor dabigatran and its orally active prodrug, dabigatran etexilate, on thrombus formation and bleeding time in rats , 2007, Thrombosis and Haemostasis.
[18] J. Stassen,et al. Antithrombotic and anticoagulant effects of the direct thrombin inhibitor dabigatran, and its oral prodrug, dabigatran etexilate, in a rabbit model of venous thrombosis , 2007, Journal of thrombosis and haemostasis : JTH.
[19] T. Ruttmann. Coagulation for the clinician. , 2006, South African journal of surgery. Suid-Afrikaanse tydskrif vir chirurgie.
[20] D. Hoppensteadt,et al. Monitoring the New Antithrombotic Drugs , 2004, Seminars in thrombosis and hemostasis.
[21] M. Li,et al. Specific inhibiting characteristics of tetramethylpyrazine, one of the active ingredients of the Chinese herbal medicine 'Chuanxiong,' on platelet thrombus formation under high shear rates. , 2001, Thrombosis research.
[22] A. Vindigni,et al. Platelet Glycoprotein Ibα Binds to Thrombin Anion-binding Exosite II Inducing Allosteric Changes in the Activity of Thrombin* , 2001, The Journal of Biological Chemistry.
[23] B. Lindblad,et al. Prevention of experimental venous thrombosis in rabbits with different low molecular weight heparins, dermatan sulphate and hirudin. , 1995, Haemostasis.
[24] H. Ishihara,et al. DX-9065a, a New Synthetic, Potent Anticoagulant and Selective Inhibitor for Factor Xa , 1994, Thrombosis and Haemostasis.
[25] P. Chomczyński,et al. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. , 1987, Analytical biochemistry.
[26] G. Born,et al. The aggregation of blood platelets , 1963, The Journal of physiology.
[27] M. Chiariello,et al. Regular Article Activated platelets stimulate tissue factor expression in smooth muscle cells , 2003 .
[28] M. Chiariello,et al. Activated platelets stimulate tissue factor expression in smooth muscle cells. , 2003, Thrombosis research.