The mGluR theory of fragile X mental retardation
暂无分享,去创建一个
[1] M. Bear,et al. Therapeutic implications of the mGluR theory of fragile X mental retardation , 2005, Genes, brain, and behavior.
[2] N. Cosford,et al. Metabotropic Glutamate Receptor mGlu5 Is a Mediator of Appetite and Energy Balance in Rats and Mice , 2005, Journal of Pharmacology and Experimental Therapeutics.
[3] Yan Wang,et al. Pharmacological Rescue of Synaptic Plasticity, Courtship Behavior, and Mushroom Body Defects in a Drosophila Model of Fragile X Syndrome , 2005, Neuron.
[4] R. Huganir,et al. N-ethylmaleimide-sensitive factor is required for the synaptic incorporation and removal of AMPA receptors during cerebellar long-term depression , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[5] J. Eberwine,et al. Fragile X syndrome: (What's) lost in translation? , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[6] I. Weiler,et al. Fragile X mental retardation protein is necessary for neurotransmitter-activated protein translation at synapses. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[7] Antonio Pisani,et al. Metabotropic glutamate receptors and striatal synaptic plasticity: implications for neurological diseases , 2004, Progress in Neurobiology.
[8] G. Quirk,et al. Neuronal signalling of fear memory , 2004, Nature Reviews Neuroscience.
[9] D. Wells,et al. Rapid, Activity-Induced Increase in Tissue Plasminogen Activator Is Mediated by Metabotropic Glutamate Receptor-Dependent mRNA Translation , 2004, The Journal of Neuroscience.
[10] Joseph E LeDoux,et al. Molecular Mechanisms Underlying Emotional Learning and Memory in the Lateral Amygdala , 2004, Neuron.
[11] M. Bear,et al. LTP and LTD An Embarrassment of Riches , 2004, Neuron.
[12] Fabrizio Gasparini,et al. mGlu5 receptor antagonists: a novel class of anxiolytics? , 2004, Drug news & perspectives.
[13] R. Carroll,et al. Metabotropic Glutamate Receptor Activation Regulates Fragile X Mental Retardation Protein and Fmr1 mRNA Localization Differentially in Dendrites and at Synapses , 2004, The Journal of Neuroscience.
[14] Daniela C. Zarnescu,et al. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway , 2004, Nature Neuroscience.
[15] G. Collingridge,et al. An investigation of depotentiation of long-term potentiation in the CA1 region of the hippocampus , 1994, Experimental Brain Research.
[16] H. Wiśniewski,et al. Adult fragile X syndrome , 1985, Acta Neuropathologica.
[17] I. Tarkka,et al. Augmentation of Auditory N1 in Children with Fragile X Syndrome , 2004, Brain Topography.
[18] B. Oostra,et al. Understanding the biological underpinnings of fragile X syndrome , 2003, Current opinion in pediatrics.
[19] M. Geyer,et al. Disruption of prepulse inhibition in mice lacking mGluR1 , 2003, The European journal of neuroscience.
[20] Peter K. Todd,et al. The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95 , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[21] Dominique Debanne,et al. Long-Term Enhancement of Neuronal Excitability and Temporal Fidelity Mediated by Metabotropic Glutamate Receptor Subtype 5 , 2003, The Journal of Neuroscience.
[22] S. Endo,et al. ERKs regulate PKC-dependent synaptic depression and declustering of glutamate receptors in cerebellar Purkinje cells , 2003, Neuropharmacology.
[23] B. Oostra,et al. Understanding fragile X syndrome: insights from animal models , 2003, Cytogenetic and Genome Research.
[24] O. Steward,et al. Compartmentalized Synthesis and Degradation of Proteins in Neurons , 2003, Neuron.
[25] L. Chen,et al. The fragile x mental retardation protein binds and regulates a novel class of mRNAs containing u rich target sequences , 2003, Neuroscience.
[26] E. Pralong,et al. Activation of Metabotropic Glutamate 5 and NMDA Receptors Underlies the Induction of Persistent Bursting and Associated Long-Lasting Changes in CA3 Recurrent Connections , 2003, The Journal of Neuroscience.
[27] T. Tachibana,et al. Immunohistochemical expressions of mGluR5, P2Y2 receptor, PLC-β1, and IP3R-I and -II in Merkel cells in rat sinus hair follicles , 2003, Histochemistry and Cell Biology.
[28] David M. Lovinger,et al. It could be habit forming: drugs of abuse and striatal synaptic plasticity , 2003, Trends in Neurosciences.
[29] Sukchan Lee,et al. Translation of clock rhythmicity into neural firing in suprachiasmatic nucleus requires mGluR–PLCβ4 signaling , 2003, Nature Neuroscience.
[30] Gavin Rumbaugh,et al. Phosphorylation of the AMPA Receptor GluR1 Subunit Is Required for Synaptic Plasticity and Retention of Spatial Memory , 2003, Cell.
[31] R. Kooy. Of mice and the fragile X syndrome. , 2003, Trends in genetics : TIG.
[32] P. Jin,et al. New insights into fragile X syndrome: from molecules to neurobehaviors. , 2003, Trends in biochemical sciences.
[33] Sreedharan Sajikumar,et al. Anisomycin inhibits the late maintenance of long-term depression in rat hippocampal slices in vitro , 2003, Neuroscience Letters.
[34] G. Bassell,et al. Sunrise at the Synapse The FMRP mRNP Shaping the Synaptic Interface , 2003, Neuron.
[35] B. Oostra,et al. The Fragile X Syndrome Protein FMRP Associates with BC1 RNA and Regulates the Translation of Specific mRNAs at Synapses , 2003, Cell.
[36] I. Weiler,et al. RNA Cargoes Associating with FMRP Reveal Deficits in Cellular Functioning in Fmr1 Null Mice , 2003, Neuron.
[37] P. Calabresi,et al. Corticostriatal LTP requires combined mGluR1 and mGluR5 activation , 2003, Neuropharmacology.
[38] R. Hunt,et al. Evolving concepts in functional gastrointestinal disorders: promising directions for novel pharmaceutical treatments. , 2002, Best practice & research. Clinical gastroenterology.
[39] A. Iacoangeli,et al. Dendritic BC1 RNA: Functional Role in Regulation of Translation Initiation , 2002, The Journal of Neuroscience.
[40] K. Hsu,et al. The Group I Metabotropic Glutamate Receptor Agonist (S)-3,5-Dihydroxyphenylglycine Induces a Novel Form of Depotentiation in the CA1 Region of the Hippocampus , 2002, The Journal of Neuroscience.
[41] C. Saper,et al. The Need to Feed Homeostatic and Hedonic Control of Eating , 2002, Neuron.
[42] M. Siomi,et al. A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. , 2002, Genes & development.
[43] A. Caudy,et al. Fragile X-related protein and VIG associate with the RNA interference machinery. , 2002, Genes & development.
[44] R. Wong,et al. Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices. , 2002, Journal of neurophysiology.
[45] S. Siegelbaum,et al. Altered Presynaptic Vesicle Release and Cycling during mGluR-Dependent LTD , 2002, Neuron.
[46] Norio Ishida,et al. A Role for the Drosophila Fragile X-Related Gene in Circadian Output , 2002, Current Biology.
[47] I. Weiler,et al. Dendritic spine and dendritic field characteristics of layer V pyramidal neurons in the visual cortex of fragile-X knockout mice. , 2002, American journal of medical genetics.
[48] Joseph E LeDoux,et al. The Group I Metabotropic Glutamate Receptor mGluR5 Is Required for Fear Memory Formation and Long-Term Potentiation in the Lateral Amygdala , 2002, The Journal of Neuroscience.
[49] K. Siwicki,et al. Drosophila Lacking dfmr1 Activity Show Defects in Circadian Output and Fail to Maintain Courtship Interest , 2002, Neuron.
[50] Andrew J. Schroeder,et al. Drosophila Fragile X Protein, DFXR, Regulates Neuronal Morphology and Function in the Brain , 2002, Neuron.
[51] Mark F. Bear,et al. Altered synaptic plasticity in a mouse model of fragile X mental retardation , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[52] R. Wong,et al. Metabotropic Glutamate Receptors and Epileptogenesis , 2002, Epilepsy currents.
[53] D. Lovinger,et al. Postsynaptic endocannabinoid release is critical to long-term depression in the striatum , 2002, Nature Neuroscience.
[54] Darci M. Nielsen,et al. Alterations in the auditory startle response in Fmr1 targeted mutant mouse models of fragile X syndrome , 2002, Brain Research.
[55] P. Carlen,et al. Reduced Cortical Synaptic Plasticity and GluR1 Expression Associated with Fragile X Mental Retardation Protein Deficiency , 2002, Molecular and Cellular Neuroscience.
[56] Gerald M Edelman,et al. Dendritic spines elongate after stimulation of group 1 metabotropic glutamate receptors in cultured hippocampal neurons , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[57] Stephen T Warren,et al. A decade of molecular studies of fragile X syndrome. , 2002, Annual review of neuroscience.
[58] A. Reeve,et al. mGlu5 receptors and nociceptive function II. mGlu5 receptors functionally expressed on peripheral sensory neurones mediate inflammatory hyperalgesia , 2001, Neuropharmacology.
[59] Gerald M. Rubin,et al. Drosophila Fragile X-Related Gene Regulates the MAP1B Homolog Futsch to Control Synaptic Structure and Function , 2001, Cell.
[60] J. Darnell,et al. Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X Syndrome , 2001, Cell.
[61] J. Darnell,et al. Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function , 2001, Cell.
[62] Roger A. Nicoll,et al. Metabotropic glutamate receptor activation causes a rapid redistribution of AMPA receptors , 2001, Neuropharmacology.
[63] J. Mandel,et al. The Fragile X mental retardation protein , 2001, Brain Research Bulletin.
[64] Mark F. Bear,et al. Internalization of ionotropic glutamate receptors in response to mGluR activation , 2001, Nature Neuroscience.
[65] J. Eberwine,et al. Identification of sites for exponential translation in living dendrites , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[66] Stefan Offermanns,et al. Gαq-Deficient Mice Lack Metabotropic Glutamate Receptor-Dependent Long-Term Depression But Show Normal Long-Term Potentiation in the Hippocampal CA1 Region , 2001, The Journal of Neuroscience.
[67] Karel Svoboda,et al. Abnormal Development of Dendritic Spines inFMR1 Knock-Out Mice , 2001, The Journal of Neuroscience.
[68] M. Ito,et al. Induction of long-term depression in cerebellar Purkinje cells requires a rapidly turned over protein. , 2001, Journal of neurophysiology.
[69] W. Spooren,et al. Novel allosteric antagonists shed light on mglu(5) receptors and CNS disorders. , 2001, Trends in pharmacological sciences.
[70] M. Bear,et al. Chemical induction of mGluR5- and protein synthesis--dependent long-term depression in hippocampal area CA1. , 2001, Journal of neurophysiology.
[71] S. Warren,et al. The fragile X mental retardation protein inhibits translation via interacting with mRNA. , 2001, Nucleic acids research.
[72] L. Chen,et al. Fragile X mice develop sensory hyperreactivity to auditory stimuli , 2001, Neuroscience.
[73] F. Gasparini,et al. Potential anxiolytic‐ and antidepressant‐like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist , 2001, British journal of pharmacology.
[74] A. Ostareck-Lederer,et al. Evidence that fragile X mental retardation protein is a negative regulator of translation. , 2001, Human molecular genetics.
[75] I. Weiler,et al. Abnormal dendritic spine characteristics in the temporal and visual cortices of patients with fragile-X syndrome: a quantitative examination. , 2001, American journal of medical genetics.
[76] S. Offermanns,et al. G(alpha)q-deficient mice lack metabotropic glutamate receptor-dependent long-term depression but show normal long-term potentiation in the hippocampal CA1 region. , 2001, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[77] O. Steward,et al. Protein synthesis at synaptic sites on dendrites. , 2001, Annual review of neuroscience.
[78] D. Manahan‐Vaughan,et al. Requirement of Translation But Not Transcription for the Maintenance of Long-Term Depression in the CA1 Region of Freely Moving Rats , 2000, The Journal of Neuroscience.
[79] Ann M Graybiel,et al. Toward a Neurobiology of Obsessive-Compulsive Disorder , 2000, Neuron.
[80] A. Graybiel,et al. Levodopa-induced dyskinesias and dopamine-dependent stereotypies: a new hypothesis , 2000, Trends in Neurosciences.
[81] B. Meldrum,et al. Anticonvulsant activity of two metabotropic glutamate Group I antagonists selective for the mGlu5 receptor: 2-methyl-6-(phenylethynyl)-pyridine (MPEP), and (E)-6-methyl-2-styryl-pyridine (SIB 1893) , 2000, Neuropharmacology.
[82] M. Bear,et al. Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression. , 2000, Science.
[83] A. Kirchgessner,et al. Agonist- and Reflex-Evoked Internalization of Metabotropic Glutamate Receptor 5 in Enteric Neurons , 2000, The Journal of Neuroscience.
[84] W. Abraham,et al. Metabotropic Glutamate Receptors Trigger Homosynaptic Protein Synthesis to Prolong Long-Term Potentiation , 2000, The Journal of Neuroscience.
[85] H. Moser,et al. Dendritic anomalies in disorders associated with mental retardation. , 1999, Cerebral cortex.
[86] J. Wood,et al. Functional group I metabotropic glutamate receptors in submucous plexus of guinea‐pig ileum , 1999, British journal of pharmacology.
[87] S. T. Warren,et al. Fragile X mouse: strain effects of knockout phenotype and evidence suggesting deficient amygdala function , 1999, Neuroscience.
[88] W. Willis,et al. Role of metabotropic glutamate receptor subtype mGluR1 in brief nociception and central sensitization of primate STT cells. , 1999, Journal of neurophysiology.
[89] Mark von Zastrow,et al. Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures , 1999, Nature Neuroscience.
[90] Z. Bashir,et al. Induction of LTD in the adult hippocampus by the synaptic activation of AMPA/kainate and metabotropic glutamate receptors , 1999, Neuropharmacology.
[91] R. Morris,et al. Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein , 1998, Nature.
[92] Peter Somogyi,et al. Cell Type and Pathway Dependence of Synaptic AMPA Receptor Number and Variability in the Hippocampus , 1998, Neuron.
[93] P. Bergold,et al. Requirement of protein synthesis for group I mGluR-mediated induction of epileptiform discharges. , 1998, Journal of neurophysiology.
[94] A. Graybiel. The Basal Ganglia and Chunking of Action Repertoires , 1998, Neurobiology of Learning and Memory.
[95] C. Shatz,et al. Mechanistic relationships between development and learning , 1998 .
[96] E O Wilson,et al. Consilience among the great branches of learning. , 1998, Daedalus.
[97] D. Absher,et al. FMRP associates with polyribosomes as an mRNP, and the I304N mutation of severe fragile X syndrome abolishes this association. , 1997, Molecular cell.
[98] G. R. Seabrook,et al. The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus , 1997, Neuropharmacology.
[99] T. Schikorski,et al. Quantitative Ultrastructural Analysis of Hippocampal Excitatory Synapses Materials and Methods Terminology Fixation and Embedding , 2022 .
[100] J. Roder,et al. Mice Lacking Metabotropic Glutamate Receptor 5 Show Impaired Learning and Reduced CA1 Long-Term Potentiation (LTP) But Normal CA3 LTP , 1997, The Journal of Neuroscience.
[101] R. Nicoll,et al. Two Distinct Forms of Long-Term Depression Coexist in CA1 Hippocampal Pyramidal Cells , 1997, Neuron.
[102] I. Weiler,et al. Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[103] S. Hersch,et al. Fragile X Mental Retardation Protein: Nucleocytoplasmic Shuttling and Association with Somatodendritic Ribosomes , 1997, The Journal of Neuroscience.
[104] N. Alpert,et al. Probing striatal function in obsessive-compulsive disorder: a PET study of implicit sequence learning. , 1997, The Journal of neuropsychiatry and clinical neurosciences.
[105] R. D'Hooge,et al. Long-term potentiation in the hippocampus of fragile X knockout mice. , 1996, American journal of medical genetics.
[106] W. Abraham,et al. Facilitation of long-term potentiation by prior activation of metabotropic glutamate receptors. , 1996, Journal of neurophysiology.
[107] A. N. van den Pol,et al. Metabotropic glutamate receptor mGluR5 subcellular distribution and developmental expression in hypothalamus , 1995, The Journal of comparative neurology.
[108] S. Tonegawa,et al. Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice , 1994, Cell.
[109] Guy Nagels,et al. Fmr1 knockout mice: A model to study fragile X mental retardation , 1994, Cell.
[110] S. Nakanishi,et al. Antibodies inactivating mGluR1 metabotropic glutamate receptor block long-term depression in cultured Purkinje cells , 1994, Neuron.
[111] D. Linden,et al. Long-term synaptic depression in the mammalian brain , 1994, Neuron.
[112] I. Weiler,et al. Metabotropic glutamate receptors trigger postsynaptic protein synthesis. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[113] M. Bear,et al. Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[114] W. Brown,et al. Analysis of neocortex in three males with the fragile X syndrome. , 1991, American journal of medical genetics.
[115] J. Warter. Genes, brain and behavior. , 1991, Research publications - Association for Research in Nervous and Mental Disease.
[116] Silverman,et al. Fragile X Syndrome Diagnosis Treatment And Research , 2016 .
[117] KM Harris,et al. Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[118] Y. Prigent. [Long term depression]. , 1989, Annales medico-psychologiques.
[119] Masao Ito,et al. Climbing fibre induced depression of both mossy fibre responsiveness and glutamate sensitivity of cerebellar Purkinje cells , 1982, The Journal of physiology.
[120] D. Purpura,et al. Dendritic Spine "Dysgenesis" and Mental Retardation , 1974, Science.