DNA demethylation overcomes attenuation of colchicine biosynthesis in an endophytic fungus Diaporthe.

[1]  I. Trougakos,et al.  Cercospora sp. as a source of anti-aging polyketides targeting 26S proteasome and scale-up production in submerged bioreactor. , 2019, Journal of biotechnology.

[2]  G. Sivakumar.  Upstream biomanufacturing of pharmaceutical colchicine , 2018, Critical reviews in biotechnology.

[3]  U. Güldener,et al.  Elucidation of the Two H3K36me3 Histone Methyltransferases Set2 and Ash1 in Fusarium fujikuroi Unravels Their Different Chromosomal Targets and a Major Impact of Ash1 on Genome Stability , 2017, Genetics.

[4]  G. S. Shekhawat,et al.  Critical Review on Steviol Glycosides: Pharmacological, Toxicological and Therapeutic Aspects of High Potency Zero Caloric Sweetener , 2017 .

[5]  M. Seidl.  Adenine N6-methylation in diverse fungi , 2017, Nature Genetics.

[6]  K. Veselkov,et al.  A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments , 2016, Computational and structural biotechnology journal.

[7]  K. Satyamoorthy,et al.  Modulation of genetic clusters for synthesis of bioactive molecules in fungal endophytes: A review. , 2016, Microbiological research.

[8]  B. L. Manjunatha,et al.  Restoration of camptothecine production in attenuated endophytic fungus on re-inoculation into host plant and treatment with DNA methyltransferase inhibitor , 2015, World journal of microbiology & biotechnology.

[9]  R. Dean,et al.  Genome-wide profiling of DNA methylation provides insights into epigenetic regulation of fungal development in a plant pathogenic fungus, Magnaporthe oryzae , 2015, Scientific Reports.

[10]  T. S. Suryanarayanan,et al.  A search for antiplasmodial metabolites among fungal endophytes of terrestrial and marine plants of southern India , 2014, Acta Parasitologica.

[11]  J. Fulnecek,et al.  How to interpret Methylation Sensitive Amplified Polymorphism (MSAP) profiles? , 2014, BMC Genetics.

[12]  B. L. Manjunatha,et al.  Endophytes and Plant Secondary Metabolite Synthesis: Molecular and Evolutionary Perspective , 2014 .

[13]  T. S. Murali,et al.  Fungal endophytes from two orchid species - pointer towards organ specificity , 2013 .

[14]  G. S. Shekhawat,et al.  Production, storability and morphogenic response of alginate encapsulated axillary meristems and genetic fidelity evaluation of in vitro regenerated Ceropegia bulbosa: A pharmaceutically important threatened plant species , 2013 .

[15]  B. Turner,et al.  The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing , 2013, Epigenetics & Chromatin.

[16]  S. Nayak.  Do endophytic fungi possess pathway genes for plant secondary metabolites? , 2013 .

[17]  G. S. Shekhawat,et al.  Establishment and characterization of Stevia rebaudiana (Bertoni) cell suspension culture: an in vitro approach for production of stevioside , 2012, Acta Physiologiae Plantarum.

[18]  Vijay Chandra Verma,et al.  An endophytic fungus from Azadirachta indica A. Juss. that produces azadirachtin , 2012, World journal of microbiology & biotechnology.

[19]  Lily P. H. Yang.  Oral Colchicine (Colcrys®) , 2010, Drugs.

[20]  P. Mohana Kumara,et al.  Fusarium proliferatum, an endophytic fungus from Dysoxylum binectariferum Hook.f, produces rohitukine, a chromane alkaloid possessing anti-cancer activity , 2012, Antonie van Leeuwenhoek.

[21]  M. Baum,et al.  DNA methylation regulates phenotype-dependent transcriptional activity in Candida albicans , 2011, Proceedings of the National Academy of Sciences.

[22]  P. Proksch,et al.  Fungal endophytes: unique plant inhabitants with great promises , 2011, Applied Microbiology and Biotechnology.

[23]  G. S. Shekhawat,et al.  Critical review on medicinally potent plant species: Gloriosa superba. , 2011, Fitoterapia.

[24]  Michael Spiteller,et al.  Effect of artificial reconstitution of the interaction between the plant Camptotheca acuminata and the fungal endophyte Fusarium solani on camptothecin biosynthesis. , 2011, Journal of natural products.

[25]  R. Sukumar,et al.  Endophytic fungal communities in woody perennials of three tropical forest types of the Western Ghats, southern India , 2011, Biodiversity and Conservation.

[26]  Lily P. H. Yang.  Oral Colchicine (Colcrys®) in the Treatment and Prophylaxis of Gout , 2010, Drugs & aging.

[27]  D. Zilberman,et al.  Evolution of Eukaryotic DNA Methylation and the Pursuit of Safer Sex , 2010, Current Biology.

[28]  D. Zilberman,et al.  Genome-Wide Evolutionary Analysis of Eukaryotic DNA Methylation , 2010, Science.

[29]  G. Ravikanth,et al.  Attenuation of camptothecin production and negative relation between hyphal biomass and camptothecin content in endophytic fungal strains isolated from Nothapodytes nimmoniana Grahm (Icacinaceae) , 2010 .

[30]  M. Pellegrini,et al.  Conservation and divergence of methylation patterning in plants and animals , 2010, Proceedings of the National Academy of Sciences.

[31]  P. Proksch,et al.  Fungal endophytes from higher plants: a prolific source of phytochemicals and other bioactive natural products , 2010, Fungal Diversity.

[32]  P. Proksch,et al.  Methods for isolation of marine-derived endophytic fungi and their bioactive secondary products , 2010, Nature Protocols.

[33]  G. Ravikanth,et al.  Endophytic fungal strains of Fusarium solani, from Apodytes dimidiata E. Mey. ex Arn (Icacinaceae) produce camptothecin, 10-hydroxycamptothecin and 9-methoxycamptothecin. , 2010, Phytochemistry.

[34]  Peter G Foster,et al.  Phylogenomic Analysis Demonstrates a Pattern of Rare and Ancient Horizontal Gene Transfer between Plants and Fungi[W] , 2009, The Plant Cell Online.

[35]  Wenqiang Chen,et al.  Isolation and characterization of endophytic taxol-producing fungi from Taxus chinensis , 2009, Journal of Industrial Microbiology & Biotechnology.

[36]  A. Arnold,et al.  Fungal endophytes: diversity and functional roles. , 2009, The New phytologist.

[37]  F. Sasse,et al.  Fungal endophytes and bioprospecting , 2009 .

[38]  M. Spiteller,et al.  An endophytic fungus from Camptotheca acuminata that produces camptothecin and analogues. , 2009, Journal of natural products.

[39]  G. Ravikanth,et al.  How promising are endophytic fungi as alternative sources of plant secondary metabolites , 2009 .

[40]  Clay C C Wang,et al.  Identification and Characterization of the Asperthecin Gene Cluster of Aspergillus nidulans , 2008, Applied and Environmental Microbiology.

[41]  P. van der Sluijs,et al.  Juglone Inactivates Cysteine-rich Proteins Required for Progression through Mitosis* , 2008, Journal of Biological Chemistry.

[42]  G. Lund,et al.  High-performance liquid chromatography determination of 5-methyl-2'-deoxycytidine, 2'-deoxycytidine, and other deoxynucleosides and nucleosides in DNA digests. , 2008, Analytical biochemistry.

[43]  B. Bhattacharyya,et al.  Anti‐mitotic activity of colchicine and the structural basis for its interaction with tubulin , 2008, Medicinal research reviews.

[44]  A. Salmon,et al.  Brassica oleracea displays a high level of DNA methylation polymorphism , 2008 .

[45]  T. S. Suryanarayanan,et al.  Endophytic Phomopsis species: host range and implications for diversity estimates. , 2006, Canadian journal of microbiology.

[46]  P. de Mazancourt,et al.  A novel LC-ESI-MS-MS method for sensitive quantification of colchicine in human plasma: application to two case reports. , 2006, Journal of analytical toxicology.

[47]  J. Bennett,et al.  Fungal secondary metabolism — from biochemistry to genomics , 2005, Nature Reviews Microbiology.

[48]  Wenjin Guo,et al.  Homoserine and asparagine are host signals that trigger in planta expression of a pathogenesis gene in Nectria haematococca. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[49]  B. Ghosh,et al.  Enhanced colchicine production in root cultures of Gloriosa superba by direct and indirect precursors of the biosynthetic pathway , 2002, Biotechnology Letters.

[50]  D. Scott,et al.  Surrogate transformation of perennial ryegrass,Lolium perenne, using genetically modifiedAcremonium endophyte , 1992, Molecular and General Genetics MGG.

[51]  F. Alali,et al.  Determination of colchicine in Colchicum steveni and C. hierosolymitanum (Colchicaceae): comparison between two analytical methods. , 2004, Phytochemical analysis : PCA.

[52]  D. Tilman,et al.  Fungal endophytes limit pathogen damage in a tropical tree , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[53]  H. Petty,et al.  Identification of colchicine in placental blood from patients using herbal medicines. , 2001, Chemical research in toxicology.

[54]  R. Tan,et al.  Endophytes: a rich source of functional metabolites. , 2001, Natural product reports.

[55]  D. M. Long,et al.  The induction of taxol production in the endophytic fungus—Periconia sp from Torreya grandifolia , 1998, Journal of Industrial Microbiology and Biotechnology.

[56]  F. A. Uecker,et al.  Nuclear ribosomal internal transcribed spacer phylogeny and host diversity in the coelomycete Phomopsis. , 1994 .

[57]  A. Stierle,et al.  Taxol and taxane production by Taxomyces andreanae, an endophytic fungus of Pacific yew. , 1993, Science.

[58]  T. White.  Amplification and direct sequencing of fungal ribosomal RNA genes for phylogenetics , 1990 .

[59]  G. Cordell,et al.  Nmr studies of colchicine and its photoisomers, beta- and gamma-lumicolchicines. , 1988, Journal of natural products.