Association Between Hyponatremia and Complicated Appendicitis.

PACIFIC COAST SURGICAL ASSOCIATION Association Between Hyponatremia and Complicated Appendicitis Complicated appendicitis is associated with worse outcomes among patients with acute appendicitis.1 Preoperative identification of patients with a perforated or gangrenous appendicitis may have important clinical implications regarding the timing of surgery and the suitability for nonoperative management strategies. The objective of this study was to identify clinical variables associated with the presence of complicated appendicitis.