A novel multiplex qPCR assay for detection of Plasmodium falciparum with histidine-rich protein 2 and 3 (pfhrp2 and pfhrp3) deletions in polyclonal infections

[1]  A. Adegnika,et al.  Monitoring the threatened utility of malaria rapid diagnostic tests by novel high-throughput detection of Plasmodium falciparum hrp2 and hrp3 deletions: A cross-sectional, diagnostic accuracy study , 2019, EBioMedicine.

[2]  Joana C. Silva,et al.  A multiplex qPCR approach for detection of pfhrp2 and pfhrp3 gene deletions in multiple strain infections of Plasmodium falciparum , 2019, Scientific Reports.

[3]  J. Cunningham,et al.  pfhrp2 and pfhrp3 Gene Deletions That Affect Malaria Rapid Diagnostic Tests for Plasmodium falciparum: Analysis of Archived Blood Samples From 3 African Countries , 2019, The Journal of infectious diseases.

[4]  Z. Mohamed,et al.  Genetic diversity of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and its effect on the performance of PfHRP2-based rapid diagnostic tests , 2019, BMC Research Notes.

[5]  W. Takken,et al.  Molecular quantification of Plasmodium parasite density from the blood retained in used RDTs , 2019, Scientific Reports.

[6]  L. Golassa,et al.  Prevalence and epidemiological characteristics of asymptomatic malaria based on ultrasensitive diagnostics: A cross-sectional study. , 2018, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[7]  C. Sutherland,et al.  Identifying Recrudescent Plasmodium falciparum in Treated Malaria Patients by Real-time PCR and High Resolution Melt Analysis of Genetic Diversity , 2018, Scientific Reports.

[8]  T. Clark,et al.  Global analysis of Plasmodium falciparum histidine-rich protein-2 (pfhrp2) and pfhrp3 gene deletions using whole-genome sequencing data and meta-analysis. , 2018, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

[9]  S. Meshnick,et al.  Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparum , 2018, Malaria Journal.

[10]  M. Gatton,et al.  Major Threat to Malaria Control Programs by Plasmodium falciparum Lacking Histidine-Rich Protein 2, Eritrea , 2018, Emerging infectious diseases.

[11]  J. Cunningham,et al.  Plasmodium falciparum parasites with histidine-rich protein 2 (pfhrp2) and pfhrp3 gene deletions in two endemic regions of Kenya , 2017, Scientific Reports.

[12]  B. Sjögreen,et al.  Methods to determine limit of detection and limit of quantification in quantitative real-time PCR (qPCR) , 2017, Biomolecular detection and quantification.

[13]  M. Gatton,et al.  Use of PfHRP2-only RDTs rapidly select for PfHRP2-negative parasites with serious implications for malaria case management and control , 2017 .

[14]  M. Gatton,et al.  Implications of Parasites Lacking Plasmodium falciparum Histidine-Rich Protein 2 on Malaria Morbidity and Control When Rapid Diagnostic Tests Are Used for Diagnosis , 2017, The Journal of infectious diseases.

[15]  Mulugeta Russom,et al.  Rapid diagnostic tests failing to detect Plasmodium falciparum infections in Eritrea: an investigation of reported false negative RDT results , 2017, Malaria Journal.

[16]  Hannah C. Slater,et al.  Pfhrp2-Deleted Plasmodium falciparum Parasites in the Democratic Republic of the Congo: A National Cross-sectional Survey , 2016, The Journal of infectious diseases.

[17]  J. Barnwell,et al.  Genetic Characterisation of Plasmodium falciparum Isolates with Deletion of the pfhrp2 and/or pfhrp3 Genes in Colombia: The Amazon Region, a Challenge for Malaria Diagnosis and Control , 2016, PloS one.

[18]  Peter Chiodini,et al.  Plasmodium falciparum parasites lacking histidine-rich protein 2 and 3: a review and recommendations for accurate reporting , 2014, Malaria Journal.

[19]  D. V. van Schalkwyk,et al.  Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers , 2013, Malaria Journal.

[20]  J. Baker,et al.  Transcription and Expression of Plasmodium falciparum Histidine-Rich Proteins in Different Stages and Strains: Implications for Rapid Diagnostic Tests , 2011, PloS one.

[21]  R. Hallett,et al.  Measuring the efficacy of anti-malarial drugs in vivo: quantitative PCR measurement of parasite clearance , 2010, Malaria Journal.

[22]  M. Perkins,et al.  A Large Proportion of P. falciparum Isolates in the Amazon Region of Peru Lack pfhrp2 and pfhrp3: Implications for Malaria Rapid Diagnostic Tests , 2010, PloS one.

[23]  V. Beneš,et al.  The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. , 2009, Clinical chemistry.

[24]  J. Baker,et al.  Effect of Sequence Variation in Plasmodium falciparum Histidine- Rich Protein 2 on Binding of Specific Monoclonal Antibodies: Implications for Rapid Diagnostic Tests for Malaria , 2006, Journal of Clinical Microbiology.

[25]  F. Ramos.  Report 2019 , 2019, Brazilian Business Review.

[26]  V. Pande,et al.  Genetic deletion of HRP2 and HRP3 in Indian Plasmodium falciparum population and false negative malaria rapid diagnostic test. , 2013, Acta tropica.

[27]  Organización Mundial de la Salud.  Malaria rapid diagnostic test performance: results of WHO product testing of malaria RDTs: round 1 (2008) , 2009 .