Phytochemical Studies of Acmella Caulirhiza and Spermacoce Princeae used by postpartum mothers in Nyamira County, Kenya.

Introduction: Traditional medicine have been used in health maintenance, disease prevention and treatment for example Acmella caulirhiza used to treat a child’s mouth sores and Spermacoce princeae used to accelerate healing of umbilical cord and to clean the system after birth. Objective: The main objective of the present study was to determine phytochemical compounds of A. caulirhiza and S. princeae used by postpartum mothers in Nyamira County, Kenya. Methodology: The study area was Nyamira County where the two plant specimens were collected. Plant materials were identified at East Africa Herbarium. Plant specimens were transported to M.K.U. Pharmacognosy laboratory where processing was done. Phytochemical analysis methods were employed to determine phytochemicals compounds in the crude plant extracts. Data was stored in Excel spread sheet in a personal computer protected with a password. Data was presented using tables and photographs. Results: Phytochemical examinations revealed that Acmella caulirhiza contains flavonoids, terpenoids, coumarins and sterols compounds. On the other hand, Spermacoce princeae contains flavonoids, terpenoids, tannins, saponin alkaloid and glycoside compounds. Conclusion and recommendation: The plants may be used in treating puerperal sepsis although commercially available drugs are recommended as they are highly effective. The two plants can be a potent source of complementary and modern medicine. Further research is recommended to isolate and identify pure compounds of the two plants

[1]  S. Mukanganyama,et al.  Antibacterial Properties of Alkaloid Extracts from Callistemon citrinus and Vernonia adoensis against Staphylococcus aureus and Pseudomonas aeruginosa , 2016, International journal of medicinal chemistry.

[2]  A. Makokha,et al.  Types of Herbal Medicine Used for HIV Conditions in Vihiga County, Kenya , 2016 .

[3]  K. Chaudhary,et al.  Preliminary pharmacognostic and phytochemical studies on Nerium oleander Linn. (White cultivar) , 2015 .

[4]  L. Mwamburi,et al.  An Inventory of Medicinal Plants used to Treat Gynaecological-Obstetric-Urino-Genital Disorders in South Nandi Sub County in Kenya , 2015 .

[5]  A. Baysal,et al.  Antibacterial and Antioxidant Activity of Essential Oil Terpenes against Pathogenic and Spoilage-Forming Bacteria and Cell Structure-Activity Relationships Evaluated by SEM Microscopy , 2014, Molecules.

[6]  Zemede Asfaw Z. Asfaw,et al.  Use and management of traditional medicinal plants by Maale and Ari ethnic communities in southern Ethiopia , 2014, Journal of Ethnobiology and Ethnomedicine.

[7]  Antón García,et al.  Mechanisms of Antimicrobial Actions of Phytochemicals against Enteric Pathogens – A Review , 2014 .

[8]  Shakeel Ahmed,et al.  Antimicrobial activity of terpenoids from Sphaeranthus indicus. L , 2014 .

[9]  G. P. Kumar,et al.  Influence of flavonoids and glycosides from Caesalpinia coriaria (Jacq) wild as bactericidal compound , 2014 .

[10]  Faith A. Okalebo,et al.  An investigation of the antimicrobial activity of acmella caulirhiza , 2013 .

[11]  A. Pandey,et al.  Chemistry and Biological Activities of Flavonoids: An Overview , 2013, TheScientificWorldJournal.

[12]  U. Prawat,et al.  Two new cycloartane-type triterpenoids and one new flavanone from the leaves of Dasymaschalon dasymaschalum and their biological activity , 2013 .

[13]  Sameerah Ahmed Zearah,et al.  Antibacterial activity of the glycosidic extract from Citrus laurantifoia L. fruits , 2013 .

[14]  Eric Omori Omwenga,et al.  Ethnobotanical Identification and Anti-microbial Evaluation of Some Anti-Diarrhoeal Plants Used by the Samburu Community, Kenya , 2012 .

[15]  S. Sabri,et al.  PHYTOCHEMICAL SCREENING AND IDENTIFICATION OF SOME COMPOUNDS FROM MALLOW , 2012 .

[16]  Y. B. Chavan,et al.  Herbal Medicines and Nutritional supplements used in the treatment of Glaucoma: A Review , 2012 .

[17]  Geeta Singh,et al.  ANTIBACTERIAL POTENTIAL OF STEROLS OF SOME MEDICINAL PLANTS Research Article , 2012 .

[18]  M. Lemfack,et al.  Ethnopharmacological survey of plants used for the treatment of female infertility in Baham, Cameroon. , 2011, Journal of ethnopharmacology.

[19]  H. D. de Boer,et al.  Traditions and plant use during pregnancy, childbirth and postpartum recovery by the Kry ethnic group in Lao PDR , 2011, Journal of ethnobiology and ethnomedicine.

[20]  P. Jeruto,et al.  Phytochemical constituents of some medicinal plants used by the Nandis of South Nandi district, Kenya. , 2011 .

[21]  Zemede Asfaw Z. Asfaw,et al.  Ethnomedicinal study of plants used by Sheko ethnic group of Ethiopia. , 2010, Journal of ethnopharmacology.

[22]  Ashok Pandey,et al.  Therapeutic potential of C.Zeylanicum extracts: an antifungal and antioxidant perspective , 2010 .

[23]  O. Olonitola,et al.  Phytochemical screening and antimicrobial effect of the aqueous and methanolic extracts of roots of Balanites aegyptiacam (Del.) on some bacteria species. , 2010 .

[24]  Michael J. Pikal,et al.  Determination of End Point of Primary Drying in Freeze-Drying Process Control , 2010, AAPS PharmSciTech.

[25]  M. Popova,et al.  Coumarins from Angelica Lucida L. - Antibacterial Activities , 2009, Molecules.

[26]  A. Doss,et al.  Antibacterial Activity of Tannins from the Leaves of Solanum trilobatum Linn. , 2009 .

[27]  B. Fonge,et al.  Medicinal plants of Aguambu - Bamumbu in the Lebialem highlands, southwest province of Cameroon , 2009 .

[28]  A. Mishra,et al.  Inhibitory activity of Indian spice plant Cinnamomum zeylanicum extracts against Alternaria solani and Curvularia lunata, the pathogenic dematiaceous moulds , 2009, Annals of Clinical Microbiology and Antimicrobials.

[29]  Hualiang Jiang,et al.  Three flavonoids targeting the β‐hydroxyacyl‐acyl carrier protein dehydratase from Helicobacter pylori: Crystal structure characterization with enzymatic inhibition assay , 2008, Protein science : a publication of the Protein Society.

[30]  Daciana Ciocan,et al.  PLANT PRODUCTS AS ANTIMICROBIAL AGENTS , 2007 .

[31]  R. Bussmann,et al.  Journal of Ethnobiology and Ethnomedicine Open Access Traditional Management of Ear, Nose and Throat (ent) Diseases in Central Kenya , 2022 .

[32]  Marcy J. Balunas,et al.  Drug discovery from medicinal plants. , 2005, Life sciences.

[33]  Andrew J Lamb,et al.  Antimicrobial activity of flavonoids , 2005, International Journal of Antimicrobial Agents.

[34]  D. Mulholland,et al.  A novel alkylamide from the leaves of Acmella caulirhiza (Asteraceae), a traditional surface analgesic , 2005 .

[35]  F. Abulude Mineral and phytate contents of 10 vegetables grown in nigeria and calculation of their phytate:Zn and Ca:phytate molar ratios , 2001 .

[36]  V. Lakshmi,et al.  Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo. , 1996, Journal of ethnopharmacology.

[37]  Y. Tamura,et al.  Application of saponins in foods and cosmetics: saponins of Mohave yucca and Sapindus mukurossi. , 1996, Advances in experimental medicine and biology.

[38]  E. Haslam Natural polyphenols (vegetable tannins) as drugs: possible modes of action. , 1996, Journal of natural products.

[39]  G. Jones,et al.  Effects of Sainfoin (Onobrychis viciifolia Scop.) Condensed Tannins on Growth and Proteolysis by Four Strains of Ruminal Bacteria , 1994, Applied and environmental microbiology.

[40]  R. Mahunnah,et al.  Plants used in traditional medicine in eastern Tanzania. III. Angiosperms (Euphorbiaceae to Menispermaceae). , 1990, Journal of ethnopharmacology.

[41]  R. Mahunnah,et al.  Plants used in traditional medicine in eastern Tanzania. II. Angiosperms (Capparidaceae to Ebenaceae). , 1989, Journal of ethnopharmacology.

[42]  E. Haslam,et al.  Carbohydrate — Polyphenol Complexation , 1989 .

[43]  C. N. Mathur,et al.  Relationship between structure and anticoagulant activity of coumarin derivatives. , 1963, British journal of pharmacology and chemotherapy.