Why Current Publication Practices May Distort Science

John Ioannidis and colleagues argue that the current system of publication in biomedical research provides a distorted view of the reality of scientific data.

[1]  Joseph A. Schumpeter,et al.  The Instability of Capitalism , 1928 .

[2]  K. Popper,et al.  The Logic of Scientific Discovery , 1960 .

[3]  R. Merton.  Priorities in scientific discovery: A chapter in the sociology of science. , 1957 .

[4]  M. Kendall,et al.  The Logic of Scientific Discovery. , 1959 .

[5]  R. Nelson.  The Simple Economics of Basic Scientific Research , 1959, Journal of Political Economy.

[6]  Mordecai Kurz.  The Rate and Direction of Inventive Activity: Economic and Social Factors. , 1962 .

[7]  Otis Dudley Duncan,et al.  The Rate and Direction of Inventive Activity: Economic and Social Factors. , 1963 .

[8]  Michael Polanyi.  Science, Faith and Society , 1964 .

[9]  H G Johnson.  Some economic aspects of science , 1971, Ciba Foundation symposium.

[10]  E. C. Capen,et al.  Competitive Bidding in High-Risk Situations , 1971 .

[11]  N. Rosenberg.  Science, Invention and Economic Growth , 1974 .

[12]  P. Allison,et al.  Productivity Differences Among Scientists: Evidence for Accumulative Advantage , 1974 .

[13]  J. Dessauer.  Book Publishing What It Is, What It Does , 1974 .

[14]  A. Greenwald.  Consequences of Prejudice Against the Null Hypothesis , 1975 .

[15]  H. W. Winger.  : Book Publishing: What It Is, What It Does , 1976 .

[16]  J. Cassing,et al.  Implications of the Auction Mechanism in Baseball's Free Agent Draft* , 1980 .

[17]  M. F. Fox.  Publication Productivity among Scientists: A Critical Review , 1983 .

[18]  J. Hicks,et al.  The economics of science , 1996 .

[19]  James C. Cox,et al.  In Search of the Winner's Curse , 1984 .

[20]  R. Simes.  Publication bias: the case for an international registry of clinical trials. , 1986, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[21]  R. Porter,et al.  Information, Returns, and Bidding Behavior in OCS Auctions: 1954-1969 , 1987 .

[22]  K. Dickersin,et al.  Publication bias and clinical trials. , 1987, Controlled clinical trials.

[23]  R G Newcombe,et al.  Towards a reduction in publication bias. , 1987, British medical journal.

[24]  Joel B. Greenhouse,et al.  Selection Models and the File Drawer Problem , 1988 .

[25]  V. Smith,et al.  Bubbles, Crashes, and Endogenous Expectations in Experimental Spot Asset Markets , 1988 .

[26]  R. Thaler.  Anomalies: The Winner's Curse , 1988 .

[27]  Nathan Rosenberg,et al.  SCIENCE, TECHNOLOGY AND THE WESTERN MIRACLE , 1990 .

[28]  P. Easterbrook,et al.  Publication bias in clinical research , 1991, The Lancet.

[29]  Norman J. Ireland,et al.  On limiting the market for status signals , 1991 .

[30]  G. Becker,et al.  A Note on Restaurant Pricing and Other Examples of Social Influences on Price , 1991, Journal of Political Economy.

[31]  K. Pavitt.  What makes basic research economically useful , 1991 .

[32]  Will publication bias vanish in the age of online journals? , 1992, The Online journal of current clinical trials.

[33]  E. Andersen,et al.  National Systems of Innovation: Towards a Theory of Innovation and Interactive Learning , 1992 .

[34]  P. David,et al.  Toward a new economics of science , 1994 .

[35]  R. Frank,et al.  The Winner-Take-All Society , 1995 .

[36]  J. Kagel,et al.  Bidding in Common Value Auctions: How the Commercial Construction Industry Corrects for the Winner's Curse , 1996 .

[37]  R. Simes,et al.  Publication bias: evidence of delayed publication in a cohort study of clinical research projects , 1997, BMJ.

[38]  R. Wears,et al.  Positive-outcome bias and other limitations in the outcome of research abstracts submitted to a scientific meeting. , 1998, JAMA.

[39]  D G Altman,et al.  Statistical reviewing policies of medical journals: caveat lector? , 1998, Journal of general internal medicine.

[40]  S. Bikhchandani,et al.  Learning from the behavior of others : conformity, fads, and informational cascades , 1998 .

[41]  Paula E. Stephan,et al.  The Changing Rewards to Science: The Case of Biotechnology , 1998 .

[42]  Jeffrey D. Scargle,et al.  Publication Bias: The “File-Drawer” Problem in Scientific Inference , 2000 .

[43]  F. Song,et al.  The role of electronic journals in reducing publication bias. , 1999, Medical informatics and the Internet in medicine.

[44]  D. Rennie,et al.  Publication bias in editorial decision making. , 2002, JAMA.

[45]  D. Hirshleifer,et al.  Herd Behaviour and Cascading in Capital Markets: A Review and Synthesis , 2003 .

[46]  D. Kahneman.  A perspective on judgment and choice: mapping bounded rationality. , 2003, The American psychologist.

[47]  Ian F Tannock,et al.  Factors associated with failure to publish large randomized trials presented at an oncology meeting. , 2003, JAMA.

[48]  John P A Ioannidis,et al.  Translation of highly promising basic science research into clinical applications. , 2003, The American journal of medicine.

[49]  T. Bubela,et al.  Do the print media “hype” genetic research? A comparison of newspaper stories and peer-reviewed research papers , 2004, Canadian Medical Association Journal.

[50]  D. Felson,et al.  A surplus of positive trials: weighing biases and reconsidering equipoise , 2004, Arthritis research & therapy.

[51]  J. Ioannidis.  Contradicted and initially stronger effects in highly cited clinical research. , 2005, JAMA.

[52]  J. Ioannidis,et al.  Local Literature Bias in Genetic Epidemiology: An Empirical Evaluation of the Chinese Literature , 2005, PLoS medicine.

[53]  Thomas A Trikalinos,et al.  Early extreme contradictory estimates may appear in published research: the Proteus phenomenon in molecular genetics research and randomized trials. , 2005, Journal of clinical epidemiology.

[54]  J. Ioannidis.  Why Most Published Research Findings Are False , 2005, PLoS medicine.

[55]  John P A Ioannidis,et al.  Selective reporting biases in cancer prognostic factor studies. , 2005, Journal of the National Cancer Institute.

[56]  Julia Andersen,et al.  Journal impact factor in the era of expanding literature. , 2006, Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.

[57]  Tam Cam Ha,et al.  The journal impact factor: too much of an impact? , 2006, Annals of the Academy of Medicine, Singapore.

[58]  J. Ioannidis,et al.  Evolution and Translation of Research Findings: From Bench to Where? , 2006, PLoS clinical trials.

[59]  The Impact Factor Game , 2006, PLoS medicine.

[60]  J. Ioannidis,et al.  Origin and funding of the most frequently cited papers in medicine: database analysis , 2006, BMJ : British Medical Journal.

[61]  Christopher F. Martin,et al.  Association of industry sponsorship to published outcomes in gastrointestinal clinical research. , 2006, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[62]  J. Sterne,et al.  The publication process itself was the major cause of publication bias in genetic epidemiology. , 2006, Journal of clinical epidemiology.

[63]  Scientific Journals: Who Impacts the Impact Factor? , 2006, The International journal of artificial organs.

[64]  John P. A. Ioannidis,et al.  Concentration of the Most-Cited Papers in the Scientific Literature: Analysis of Journal Ecosystems , 2006, PloS one.

[65]  Andrey Rzhetsky,et al.  Microparadigms: chains of collective reasoning in publications about molecular interactions. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[66]  T. Hampton,et al.  The Cancer Genome Atlas , 2020, Indian Journal of Medical and Paediatric Oncology.

[67]  Expanded Publishing Model for Genetic Association Studies , 2006, Cancer Epidemiology Biomarkers & Prevention.

[68]  John P A Ioannidis,et al.  Journals Should Publish All “Null” Results and Should Sparingly Publish “Positive” Results , 2006, Cancer Epidemiology Biomarkers & Prevention.

[69]  Richard M. Smith,et al.  Commentary: the power of the unrelenting impact factor--is it a force for good or harm? , 2006, International journal of epidemiology.

[70]  George Liberopoulos,et al.  Selection in Reported Epidemiological Risks: An Empirical Assessment , 2007, PLoS medicine.

[71]  Mabel Chew,et al.  Life and times of the impact factor: retrospective analysis of trends for seven medical journals (1994-2005) and their Editors' views. , 2007, Journal of the Royal Society of Medicine.

[72]  Mike Rossner,et al.  Show me the data , 2007, The Journal of cell biology.

[73]  G. Guyatt,et al.  Systematic reviewers neglect bias that results from trials stopped early for benefit. , 2007, Journal of clinical epidemiology.

[74]  John P A Ioannidis,et al.  Almost all articles on cancer prognostic markers report statistically significant results. , 2007, European journal of cancer.

[75]  J. Ioannidis.  Why Most Discovered True Associations Are Inflated , 2008, Epidemiology.

[76]  Steven N Goodman,et al.  Systematic reviews are not biased by results from trials stopped early for benefit. , 2008, Journal of clinical epidemiology.

[77]  R. Rosenthal,et al.  Selective publication of antidepressant trials and its influence on apparent efficacy. , 2008, The New England journal of medicine.

[78]  Book publishing , 2009, BMJ : British Medical Journal.