AMNIOTIC MEMBRANE TRANSPLANTATION IN TRABECULECTOMY

Purpose: To evaluate the effect of amniotic membrane transplantation in trabeculectomy. Methods: The study was conducted on 25 eyes of 25 patients with advanced and medically uncontrolled glaucoma. All patients underwent trabeculectomy with a fornix based conjunctival flap, amniotic membrane was then placed under the scleral flap and fixed using 10-0 nylon suture. Amniotic membrane was retrieved from healthy pregnant women during elective cesarian section. Results: Preoperative intraocular pressure was 33.5±5.0 mmHg (26-50 mmHg) with full medication, which decreased to 12.4±1.8 mmHg (9-15 mmHg) post-operatively (P= 0.0001). Intraocular pressure was less than 21 mmHg after surgery in all eyes, with (8%) or without (92%) use of antiglaucoma medications after six months. Conclusion: The use of amniotic membrane in trabeculectomy can increase the chance of success in terms of maintenance of a functional bleb and prevention of failure. This method may be superior to antimetabolites due to lack of complications.

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