hnRNP K induces HPV16 oncogene expression and promotes cervical cancerization

[1]  Rui Mao,et al.  hnRNP E1 Regulates HPV16 Oncogene Expression and Inhibits Cervical Cancerization , 2022, Frontiers in Oncology.

[2]  R. Zheng,et al.  Cancer incidence and mortality in China, 2016 , 2022, Journal of the National Cancer Center.

[3]  S. Schwartz,et al.  The role of RNA-binding proteins in the processing of mRNAs produced by carcinogenic papillomaviruses. , 2022, Seminars in cancer biology.

[4]  A. Jemal,et al.  Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries , 2021, CA: a cancer journal for clinicians.

[5]  H. Hua,et al.  Complex roles of cAMP–PKA–CREB signaling in cancer , 2020, Experimental Hematology & Oncology.

[6]  Gene W. Yeo,et al.  A Large-Scale Binding and Functional Map of Human RNA Binding Proteins , 2017, bioRxiv.

[7]  L. Ding,et al.  Effects of exposure to polycyclic aromatic hydrocarbons combined with high‐risk human papillomavirus infection on cervical intraepithelial neoplasia: A population study in Shanxi Province, China , 2019, International journal of cancer.

[8]  Junqi He,et al.  HPV16 E6 promotes cervical cancer cell migration and invasion by downregulation of NHERF1 , 2018, International journal of cancer.

[9]  Ahwon Lee,et al.  E2/E6 ratio and L1 immunoreactivity as biomarkers to determine HPV16-positive high-grade squamous intraepithelial lesions (CIN2 and 3) and cervical squamous cell carcinoma , 2018, Journal of gynecologic oncology.

[10]  R. Wei,et al.  HNRNPK inhibits gastric cancer cell proliferation through p53/p21/CCND1 pathway , 2017, Oncotarget.

[11]  N. Prevarskaya,et al.  The calcium–cancer signalling nexus , 2017, Nature Reviews Cancer.

[12]  Richard Sullivan,et al.  The global burden of women’s cancers: a grand challenge in global health , 2017, The Lancet.

[13]  S. Kar,et al.  HPV Genotypes distribution in Indian women with and without cervical carcinoma: Implication for HPV vaccination program in Odisha, Eastern India , 2017, BMC Infectious Diseases.

[14]  Y. Lao,et al.  Nujiangexathone A, a novel compound from Garcinia nujiangensis, suppresses cervical cancer growth by targeting hnRNPK. , 2016, Cancer letters.

[15]  Jing Zhong,et al.  Heterogeneous nuclear ribonucleoprotein K is overexpressed and associated with poor prognosis in gastric cancer. , 2016, Oncology reports.

[16]  B. Wall,et al.  The current management of brain metastasis in melanoma: a focus on riluzole , 2015, Expert review of neurotherapeutics.

[17]  Y. Kawasaki,et al.  Heterogeneous nuclear ribonucleoprotein K upregulates the kinetochore complex component NUF2 and promotes the tumorigenicity of colon cancer cells. , 2015, Biochemical and biophysical research communications.

[18]  Erika Ilagan,et al.  Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes , 2015, The Journal of cell biology.

[19]  Juancarlos Chan,et al.  Gene Ontology Consortium: going forward , 2014, Nucleic Acids Res..

[20]  P. Ramani,et al.  Promoter hypermethylation patterns of P16, DAPK and MGMT in oral squamous cell carcinoma: a systematic review and meta-analysis. , 2014, Indian journal of dental research : official publication of Indian Society for Dental Research.

[21]  Zhao Wei-min,et al.  Folate Deficiency and Aberrant Expression of DNA Methyltransferase 1 were Associated with Cervical Cancerization , 2014 .

[22]  Wei-min Li,et al.  Downregulation of hnRNP K by RNAi inhibits growth of human lung carcinoma cells , 2014, Oncology letters.

[23]  Ying Liang,et al.  Matrix metalloproteinase 12 is induced by heterogeneous nuclear ribonucleoprotein K and promotes migration and invasion in nasopharyngeal carcinoma , 2014, BMC Cancer.

[24]  S. Schwartz Papillomavirus transcripts and posttranscriptional regulation. , 2013, Virology.

[25]  Xiaoxiao He,et al.  Effectiveness of HPV 16 viral load and the E2/E6 ratio for the prediction of cervical cancer risk among Chinese women , 2013, Journal of medical virology.

[26]  C. Johansson,et al.  Regulation of human papillomavirus gene expression by splicing and polyadenylation , 2013, Nature Reviews Microbiology.

[27]  Peng Guan,et al.  Human papillomavirus types in 115,789 HPV‐positive women: A meta‐analysis from cervical infection to cancer , 2012, International journal of cancer.

[28]  Gene W. Yeo,et al.  Integrative genome‐wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins , 2012, Cell reports.

[29]  M. Sherman,et al.  Clinical and Pathological Heterogeneity of Cervical Intraepithelial Neoplasia Grade 3 , 2012, PloS one.

[30]  A. Ciapponi,et al.  Type-Specific HPV Prevalence in Cervical Cancer and High-Grade Lesions in Latin America and the Caribbean: Systematic Review and Meta-Analysis , 2011, PloS one.

[31]  F. Rösl,et al.  Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation , 2010, Proceedings of the National Academy of Sciences.

[32]  A. Bhattacharyya,et al.  Increased expression of the heterogeneous nuclear ribonucleoprotein K in pancreatic cancer and its association with the mutant p53 , 2010, International journal of cancer.

[33]  M. Duman-Scheel Netrin and DCC: axon guidance regulators at the intersection of nervous system development and cancer. , 2009, Current drug targets.

[34]  H. Loh,et al.  Poly(C)-binding proteins as transcriptional regulators of gene expression. , 2009, Biochemical and biophysical research communications.

[35]  Clifford A. Meyer,et al.  Model-based Analysis of ChIP-Seq (MACS) , 2008, Genome Biology.

[36]  Ruiqiang Li,et al.  SOAP: short oligonucleotide alignment program , 2008, Bioinform..

[37]  S. Graham,et al.  The alternative splicing factor hnRNP A1 is up-regulated during virus-infected epithelial cell differentiation and binds the human papillomavirus type 16 late regulatory element , 2008, Virus research.

[38]  S. Costa,et al.  Viral DNA load, physical status and E2/E6 ratio as markers to grade HPV16 positive women for high-grade cervical lesions. , 2007, Gynecologic oncology.

[39]  M. Plummer,et al.  A 2-year prospective study of human papillomavirus persistence among women with a cytological diagnosis of atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion. , 2007, The Journal of infectious diseases.

[40]  R. Wadhwa,et al.  Loss-of-function screening by randomized intracellular antibodies: Identification of hnRNP-K as a potential target for metastasis , 2007, Proceedings of the National Academy of Sciences.

[41]  G I Murray,et al.  Heterogeneous nuclear ribonucleoprotein K is over expressed, aberrantly localised and is associated with poor prognosis in colorectal cancer , 2006, British Journal of Cancer.

[42]  Stephen P. Jackson,et al.  hnRNP K: An HDM2 Target and Transcriptional Coactivator of p53 in Response to DNA Damage , 2005, Cell.

[43]  S. Schwartz,et al.  A Downstream Polyadenylation Element in Human Papillomavirus Type 16 L2 Encodes Multiple GGG Motifs and Interacts with hnRNP H , 2005, Journal of Virology.

[44]  Jerzy Ostrowski,et al.  hnRNP K: One protein multiple processes , 2004, BioEssays : news and reviews in molecular, cellular and developmental biology.

[45]  Susumu Goto,et al.  KEGG: Kyoto Encyclopedia of Genes and Genomes , 2000, Nucleic Acids Res..

[46]  G. Stark,et al.  p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[47]  J. Settleman,et al.  Inhibition of cervical carcinoma cell line proliferation by the introduction of a bovine papillomavirus regulatory gene , 1993, Journal of virology.

[48]  V. Defendi,et al.  Differential effects of human papillomavirus type 6, 16, and 18 DNAs on immortalization and transformation of human cervical epithelial cells. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[49]  L. Turek,et al.  Transcriptional regulation of the human papillomavirus‐16 E6‐E7 promoter by a keratinocyte‐dependent enhancer, and by viral E2 trans‐activator and repressor gene products: implications for cervical carcinogenesis. , 1987, The EMBO journal.