Neonatal hepatitis and extrahepatic biliary atresia associated with cytomegalovirus infection in twins.

Prenatally acquired cytomegalovirus infection in twins was temporally associated with a discordant development of neonatal hepatitis and extrahepatic biliary atresia. This case presents evidence suggesting an association between perinatal cytomegalovirus infection and selected extrahepatic biliary atresia and neonatal hepatitis. Congenital cytomegalovirus infections and cytomegalovirus hepatitis are also discussed.

[1]  R. Markin,et al.  Rapid Identification of Cytomegalovirus in Liver Allograft Biopsies by In Situ Hybridization , 1988, The American journal of surgical pathology.

[2]  Z. Weintraub,et al.  Liver findings in infantile cytomegalovirus infection: similarity to extrahepatic biliary obstruction , 1987, Histopathology.

[3]  D. Przepiorka,et al.  A single-step silver enhancement method permitting rapid diagnosis of cytomegalovirus infection in formalin-fixed, paraffin-embedded tissue sections by in situ hybridization and immunoperoxidase detection. , 1986, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[4]  W. Britt,et al.  Primary Cytomegalovirus Infection in Pregnancy: Incidence, Transmission to Fetus, and Clinical Outcome , 1987 .

[5]  C. Zuppan,et al.  Diffuse hepatic fibrosis in congenital cytomegalovirus infection. , 1986, Journal of pediatric gastroenterology and nutrition.

[6]  K. Shannon,et al.  Biliary atresia in two sets of twins. , 1985, The Journal of pediatrics.

[7]  J. Hyams,et al.  Discordance for biliary atresia in two sets of monozygotic twins. , 1985, The Journal of pediatrics.

[8]  M. Horwitz,et al.  Biliary atresia and reovirus type 3 infection. , 1982, The New England journal of medicine.

[9]  M. Finegold,et al.  Obliterative cholangitis due to cytomegalovirus: a possible precursor of paucity of intrahepatic bile ducts. , 1982, Human pathology.

[10]  K. Shannon,et al.  Studies in the etiology of extrahepatic biliary atresia: time-space clustering. , 1982, The Journal of pediatrics.

[11]  S. Werlin.  EXTRAHEPATIC BILIARY ATRESIA IN ONE OF TWINS , 1981, Acta paediatrica Scandinavica.

[12]  G. Myers,et al.  Outcome of symptomatic congenital cytomegalovirus infection: results of long-term longitudinal follow-up. , 1980, Pediatrics.

[13]  A L Smith,et al.  Studies of the aetiology of neonatal hepatitis and biliary atresia. , 1977, Archives of disease in childhood.

[14]  D. Nuss,et al.  Biliary atresia in a twin. , 1977, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[15]  J. B. Hanshaw.  Congenital cytomegalovirus infection: a fifteen year perspective. , 1971, The Journal of infectious diseases.

[16]  W. Berenberg,et al.  Long-term follow-up of cytomegalic inclusion disease of infancy. , 1970, Pediatrics.

[17]  P. Froggatt,et al.  Congenital extrahepatic biliary atresia in two brothers. , 1969, Journal of medical genetics.

[18]  P. Toghill,et al.  Cytomegalovirus infection in chronic liver disease. , 1969, Gastroenterology.

[19]  H. Eichenwald,et al.  Congenital cytomegalic inclusion disease. A longitudinal study of 20 patients. , 1969, American journal of diseases of children.

[20]  M. Thaler,et al.  Studies in neonatal hepatitis and biliary atresia. 3. Progression and regression of cirrhosis in biliary atresia. , 1968, American journal of diseases of children.

[21]  H. Stern,et al.  Cytomegalovirus infection in the newborn and in early childhood. Three atypical cases. , 1965, Lancet.

[22]  Medearis Dn.  OBSERVATIONS CONCERNING HUMAN CYTOMEGALOVIRUS INFECTION AND DISEASE. , 1964 .

[23]  D. Danks,et al.  A Genetic Study of Neonatal Obstructive Jaundice , 1963, Archives of disease in childhood.

[24]  T. H. Weller,et al.  Virologic and clinical observations on cytomegalic inclusion disease. , 1962, The New England journal of medicine.

[25]  C. Alford,et al.  Perinatal infections and maldevelopment. , 1981, Birth defects original article series.

[26]  J. B. Hanshaw,et al.  Cytomegalovirus in the perinatal period. , 1981, American journal of diseases of children.

[27]  D. Henson,et al.  Postnatal cytomegalovirus hepatitis. An autopsy and liver biopsy study. , 1974, Human pathology.

[28]  W. Shim,et al.  Racial influence on the incidence of biliary atresia. , 1974, Progress in pediatric surgery.

[29]  Landing Bh.  Considerations of the pathogenesis of neonatal hepatitis, biliary atresia and choledochal cyst--the concept of infantile obstructive cholangiopathy. , 1974 .

[30]  T. H. Weller,et al.  Cytomegalic inclusion disease of the newborn: report of case with persistent viruria. , 1960, Pediatrics.