Oxysterols and mesenchymal stem cell biology.
暂无分享,去创建一个
[1] S. Bydlowski,et al. Oxysterols in adipose tissue-derived mesenchymal stem cell proliferation and death , 2017, The Journal of Steroid Biochemistry and Molecular Biology.
[2] Maurizio Memo,et al. Clinical potentials of human pluripotent stem cells , 2017, Cell Biology and Toxicology.
[3] S. Glynn,et al. Mesenchymal stem cells: key players in cancer progression , 2017, Molecular Cancer.
[4] M. K. Hadden,et al. A molecular dynamics approach to identify an oxysterol-based hedgehog pathway inhibitor. , 2017, Biochimica et biophysica acta. General subjects.
[5] V. Lefebvre,et al. Transcriptional control of chondrocyte specification and differentiation. , 2017, Seminars in cell & developmental biology.
[6] C. Logie,et al. Cellular reprogramming for clinical cartilage repair , 2017, Cell Biology and Toxicology.
[7] J. McLachlan,et al. The Effects of Endocrine Disruptors on Adipogenesis and Osteogenesis in Mesenchymal Stem Cells: A Review , 2017, Front. Endocrinol..
[8] Kevin E. Riley,et al. Ligands of Therapeutic Utility for the Liver X Receptors , 2017, Molecules.
[9] M. Valenti,et al. Osteogenic Differentiation in Healthy and Pathological Conditions , 2016, International journal of molecular sciences.
[10] S. Dong,et al. The Signaling Pathways Involved in Chondrocyte Differentiation and Hypertrophic Differentiation , 2016, Stem cells international.
[11] NarcisiRoberto,et al. Differential Effects of Small Molecule WNT Agonists on the Multilineage Differentiation Capacity of Human Mesenchymal Stem Cells. , 2016 .
[12] L. Iuliano,et al. Free Radical-derived Oxysterols: Novel Adipokines Modulating Adipogenic Differentiation of Adipose Precursor Cells. , 2016, The Journal of clinical endocrinology and metabolism.
[13] G. Muccioli,et al. Oxysterols: From cholesterol metabolites to key mediators. , 2016, Progress in lipid research.
[14] L. Fuentes-Mera,et al. Mesenchymal Stem Cells Subpopulations: Application for Orthopedic Regenerative Medicine , 2016, Stem cells international.
[15] I. Vattulainen,et al. Cholesterol oxidation products and their biological importance. , 2016, Chemistry and physics of lipids.
[16] G. Duda,et al. Treatment with recombinant human bone morphogenetic protein 7 leads to a transient induction of neutralizing autoantibodies in a subset of patients , 2016, BBA clinical.
[17] S. Midha,et al. Osteogenic signaling on silk-based matrices. , 2016, Biomaterials.
[18] D. Agrawal,et al. Key transcription factors in the differentiation of mesenchymal stem cells. , 2016, Differentiation; research in biological diversity.
[19] C. Shuai,et al. MicroRNAs regulate signaling pathways in osteogenic differentiation of mesenchymal stem cells (Review) , 2016, Molecular medicine reports.
[20] T. Einhorn,et al. Bone healing in 2016. , 2016, Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases.
[21] M. K. Hadden,et al. Synthesis and Evaluation of Osteogenic Oxysterols as Hedgehog Pathway Activators , 2016, ChemMedChem.
[22] T. Gorojankina. Hedgehog signaling pathway: a novel model and molecular mechanisms of signal transduction , 2016, Cellular and Molecular Life Sciences.
[23] I. Gelissen,et al. Oxysterols: Old Tale, New Twists. , 2016, Annual review of pharmacology and toxicology.
[24] A. Regassa,et al. Molecular Regulation of Adipogenesis and Potential Anti-Adipogenic Bioactive Molecules , 2016, International journal of molecular sciences.
[25] Z. Ge,et al. Evolving concepts of chondrogenic differentiation: history, state-of-the-art and future perspectives. , 2015, European cells & materials.
[26] M. Heiland,et al. Purmorphamine and oxysterols accelerate and promote osteogenic differentiation of mesenchymal stem cells in vitro. , 2015, In vivo.
[27] I. Kwon,et al. Mitochondrial function contributes to oxysterol-induced osteogenic differentiation in mouse embryonic stem cells. , 2015, Biochimica et biophysica acta.
[28] A. Lassar,et al. A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation , 2015, Development.
[29] S. Bydlowski,et al. ABCB1, ABCC1, and LRP gene expressions are altered by LDL, HDL, and serum deprivation in a human doxorubicin-resistant uterine sarcoma cell line. , 2015, Biochemical and biophysical research communications.
[30] A. Regassa,et al. Transcriptome analysis of hen preadipocytes treated with an adipogenic cocktail (DMIOA) with or without 20(S)-hydroxylcholesterol , 2015, BMC Genomics.
[31] P. Zuk,et al. In Vitro Osteoinductive Effects of Hydroxycholesterol on Human Adipose-Derived Stem Cells Are Mediated through the Hedgehog Signaling Pathway , 2014, Plastic and reconstructive surgery.
[32] Sigrid Nachtergaele,et al. A Novel Osteogenic Oxysterol Compound for Therapeutic Development to Promote Bone Growth: Activation of Hedgehog Signaling and Osteogenesis Through Smoothened Binding , 2014, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[33] S. Sozzani,et al. LXR‐dependent and ‐independent effects of oxysterols on immunity and tumor growth , 2014, European journal of immunology.
[34] A. Mikos,et al. Enhancing chondrogenic phenotype for cartilage tissue engineering: monoculture and coculture of articular chondrocytes and mesenchymal stem cells. , 2014, Tissue engineering. Part B, Reviews.
[35] A. Ferreira,et al. Short-term effects of 7-ketocholesterol on human adipose tissue mesenchymal stem cells in vitro. , 2014, Biochemical and biophysical research communications.
[36] S. Krauss,et al. Metabolites in vertebrate Hedgehog signaling. , 2014, Biochemical and biophysical research communications.
[37] A. James,et al. Review of Signaling Pathways Governing MSC Osteogenic and Adipogenic Differentiation , 2013, Scientifica.
[38] P. Ingham,et al. Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling , 2013, eLife.
[39] J. Handschel,et al. Effects of dexamethasone, ascorbic acid and β-glycerophosphate on the osteogenic differentiation of stem cells in vitro , 2013, Stem Cell Research & Therapy.
[40] W. Kim,et al. Effects of oleic acid and chicken serum on the expression of adipogenic transcription factors and adipogenic differentiation in hen preadipocytes , 2013, Cell biology international.
[41] Benjamin R. Myers,et al. Hedgehog pathway modulation by multiple lipid binding sites on the smoothened effector of signal response. , 2013, Developmental cell.
[42] C. Glass,et al. Sterols and oxysterols in immune cell function , 2013, Nature Immunology.
[43] P. Zuk,et al. In Vitro Study of a Novel Oxysterol for Osteogenic Differentiation on Rabbit Bone Marrow Stromal Cells , 2013, Plastic and reconstructive surgery.
[44] Yangqing Xu,et al. Oxysterol binding to the extracellular domain of Smoothened in Hedgehog signaling , 2013, Nature chemical biology.
[45] Michael S. Pepper,et al. Adipocyte and adipogenesis. , 2013, European journal of cell biology.
[46] エクストレーム,カリン,et al. Osteogenic differentiation of mesenchymal stem cells , 2013 .
[47] S. Allahverdian,et al. Oxysterol generation and liver X receptor-dependent reverse cholesterol transport: Not all roads lead to Rome , 2013, Molecular and Cellular Endocrinology.
[48] F. Mallein-Gerin,et al. Increased Adipogenesis in Cultured Embryonic Chondrocytes and in Adult Bone Marrow of Dominant Negative Erg Transgenic Mice , 2012, PloS one.
[49] S. Bydlowski,et al. Protective effects of human amniotic fluid stem cells in a model of aorta allograft vasculopathy in rats. , 2012, Transplantation proceedings.
[50] M. K. Hadden,et al. Structure-activity relationships for side chain oxysterol agonists of the hedgehog signaling pathway. , 2012, ACS medicinal chemistry letters.
[51] Tomas Jakobsson,et al. Liver X receptor biology and pharmacology: new pathways, challenges and opportunities. , 2012, Trends in pharmacological sciences.
[52] A. Moron,et al. Evaluation of Distinct Freezing Methods and Cryoprotectants for Human Amniotic Fluid Stem Cells Cryopreservation , 2012, Journal of biomedicine & biotechnology.
[53] V. Olkkonen,et al. Oxysterols and Their Cellular Effectors , 2012, Biomolecules.
[54] P. Schlesinger,et al. Oxysterols are allosteric activators of the oncoprotein Smoothened , 2011, Nature chemical biology.
[55] S. Bydlowski,et al. The potential use of stem cells derived from human amniotic fluid in renal diseases , 2011, Kidney international supplements.
[56] F. Parhami,et al. Novel oxysterols have pro‐osteogenic and anti‐adipogenic effects in vitro and induce spinal fusion in vivo , 2011, Journal of cellular biochemistry.
[57] R. Sato. Sterol metabolism and SREBP activation. , 2010, Archives of biochemistry and biophysics.
[58] M. Cohen Jr.,et al. Hedgehog signaling update. , 2010, American journal of medical genetics. Part A.
[59] Andrew J. Brown,et al. Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasis. , 2009, Molecular aspects of medicine.
[60] S. Kato,et al. Molecular switching of osteoblastogenesis versus adipogenesis: implications for targeted therapies , 2009, Expert opinion on therapeutic targets.
[61] M. Lazar,et al. New developments in adipogenesis , 2009, Trends in Endocrinology & Metabolism.
[62] M. Makishima,et al. Suppression of beta-catenin signaling by liver X receptor ligands. , 2009, Biochemical pharmacology.
[63] F. Parhami,et al. Oxysterol‐induced osteogenic differentiation of marrow stromal cells is regulated by Dkk‐1 inhibitable and PI3‐kinase mediated signaling , 2008, Journal of cellular biochemistry.
[64] M. Kassem,et al. Human mesenchymal stem cells: from basic biology to clinical applications , 2008, Gene Therapy.
[65] F. Parhami,et al. Oxysterols enhance osteoblast differentiation in vitro and bone healing in vivo , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.
[66] F. Parhami,et al. 20(S)‐Hydroxycholesterol Inhibits PPARγ Expression and Adipogenic Differentiation of Bone Marrow Stromal Cells Through a Hedgehog‐Dependent Mechanism , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[67] F. Parhami,et al. Oxysterol‐induced osteoblastic differentiation of pluripotent mesenchymal cells is mediated through a PKC‐ and PKA‐dependent pathway , 2007, Journal of cellular biochemistry.
[68] S. Nelson,et al. Oxysterols Are Novel Activators of the Hedgehog Signaling Pathway in Pluripotent Mesenchymal Cells* , 2007, Journal of Biological Chemistry.
[69] T. Willson,et al. Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma. , 2007, Molecular cell.
[70] C. Tabin,et al. BMP2 activity, although dispensable for bone formation, is required for the initiation of fracture healing , 2006, Nature Genetics.
[71] L. Lin,et al. Runx2 Overexpression Enhances Osteoblastic Differentiation and Mineralization in Adipose - Derived Stem Cells in vitro and in vivo , 2006, Calcified Tissue International.
[72] Lindolfo da Silva Meirelles,et al. Mesenchymal stem cells reside in virtually all post-natal organs and tissues , 2006, Journal of Cell Science.
[73] M. Scott,et al. Oxysterols stimulate Sonic hedgehog signal transduction and proliferation of medulloblastoma cells. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[74] H. Ryoo,et al. Critical molecular switches involved in BMP-2-induced osteogenic differentiation of mesenchymal cells. , 2006, Gene.
[75] Xin Zhang,et al. Laboratory Investigations Runx2 Overexpression Enhances Osteoblastic Differentiation and Mineralization in Adipose - Derived Stem Cells in vitro and in vivo , 2006 .
[76] D. Prockop,et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. , 2006, Cytotherapy.
[77] Y. Shih,et al. Cholesterol-3-beta, 5-alpha, 6-beta-triol induced genotoxicity through reactive oxygen species formation. , 2005, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
[78] M. Fishbein,et al. Role for Sterol Regulatory Element-Binding Protein in Activation of Endothelial Cells by Phospholipid Oxidation Products , 2004, Circulation research.
[79] J. Breslow,et al. Intracellular Cholesterol Transport , 2004, Arteriosclerosis, thrombosis, and vascular biology.
[80] D. Shouhed,et al. Oxysterols Regulate Differentiation of Mesenchymal Stem Cells: Pro‐Bone and Anti‐Fat , 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[81] Kozo Nakamura,et al. PPARgamma insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors. , 2004, The Journal of clinical investigation.
[82] R. Morrison,et al. Peroxisome-proliferator-activated receptor gamma suppresses Wnt/beta-catenin signalling during adipogenesis. , 2003, The Biochemical journal.
[83] W. Hozack,et al. Transforming Growth Factor-β-mediated Chondrogenesis of Human Mesenchymal Progenitor Cells Involves N-cadherin and Mitogen-activated Protein Kinase and Wnt Signaling Cross-talk* , 2003, Journal of Biological Chemistry.
[84] Marie-Christine Chaboissier,et al. The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. , 2002, Genes & development.
[85] D. Ramji,et al. CCAAT/enhancer-binding proteins: structure, function and regulation. , 2002, The Biochemical journal.
[86] Tomoki Aoyama,et al. Clonal heterogeneity in differentiation potential of immortalized human mesenchymal stem cells. , 2002, Biochemical and biophysical research communications.
[87] Jay R Lieberman,et al. The role of growth factors in the repair of bone. Biology and clinical applications. , 2002, The Journal of bone and joint surgery. American volume.
[88] K. Seuwen,et al. Stem cell characteristics of human trabecular bone-derived cells. , 2002, Bone.
[89] B. Spiegelman,et al. C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. , 2002, Genes & development.
[90] D. Mangelsdorf,et al. Oxysterol stimulation of epidermal differentiation is mediated by liver X receptor-beta in murine epidermis. , 2002, The Journal of investigative dermatology.
[91] P. Reaven,et al. Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol. , 2002, Journal of lipid research.
[92] A. Lopes,et al. Differential effects of enzymatic treatments on the storage and secretion of von Willebrand factor by human endothelial cells. , 2001, Thrombosis research.
[93] M. Jaye,et al. PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. , 2000, Nature medicine.
[94] D Tabor,et al. Regulation of gene expression by SREBP and SCAP. , 2000, Biochimica et biophysica acta.
[95] D. Russell,et al. Oxysterol biosynthetic enzymes. , 2000, Biochimica et biophysica acta.
[96] J. Gimble,et al. Is there a therapeutic opportunity to either prevent or treat osteopenic disorders by inhibiting marrow adipogenesis? , 2000, Bone.
[97] P. Robey. Stem cells near the century mark. , 2000, The Journal of clinical investigation.
[98] D. Mangelsdorf,et al. Oxysterols induce differentiation in human keratinocytes and increase Ap-1-dependent involucrin transcription. , 2000, Journal of Investigative Dermatology.
[99] F. Gage,et al. Mammalian neural stem cells. , 2000, Science.
[100] N. Kulagina,et al. Fibroblast precursors in normal and irradiated mouse hematopoietic organs. , 1976, Experimental hematology.