Bioprocessing of Human Pluripotent Stem Cells for Cell Therapy Applications

Human pluripotent stem cells (hPSCs), with their unique characteristics for indefinite proliferation and pluripotency, are an appealing source for cell replacement therapies, tissue engineering, drug discovery and in vitro toxicology. For the clinical implementation of these cells, there is the need for translating the culture protocols developed at research laboratories into validated bioprocesses that can guarantee reproducibility, scalability, standardization, robustness and safety.

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