Monitoring macular pigment changes in macular holes using fluorescence lifetime imaging ophthalmoscopy

To investigate the impact of macular pigment (MP) on fundus autofluorescence (FAF) lifetimes in vivo by characterizing full‐thickness idiopathic macular holes (MH) and macular pseudo‐holes (MPH).

[1]  A. Hendrickson,et al.  Distribution of cones in human and monkey retina: individual variability and radial asymmetry. , 1987, Science.

[2]  E Yamada,et al.  Some structural features of the fovea centralis in the human retina. , 1969, Archives of ophthalmology.

[3]  J. J. Wang,et al.  Prevalence and associations of epiretinal membranes. The Blue Mountains Eye Study, Australia. , 1997, Ophthalmology.

[4]  Jim Stack,et al.  Macular pigment, visual function, and macular disease among subjects with Alzheimer's disease: an exploratory study. , 2014, Journal of Alzheimer's disease : JAD.

[5]  G. Kokame.  Reappraisal of biomicroscopic classification of stages of development of a macular hole. , 1995, American journal of ophthalmology.

[6]  S. Cohen,et al.  Macular hole following severe hypertensive retinopathy. , 1994, Archives of ophthalmology.

[7]  W. Green,et al.  A HISTOPATHOLOGIC STUDY OF MACULAR CYSTS AND HOLES , 2005, Retina.

[8]  Peter M. G. Munro,et al.  Macular hole opercula. Ultrastructural features and clinicopathological correlation. , 1997, Archives of ophthalmology.

[9]  R. Klein,et al.  The epidemiology of epiretinal membranes. , 1994, Transactions of the American Ophthalmological Society.

[10]  Z. Gregor,et al.  Incidence of idiopathic full-thickness macular holes in fellow eyes. A 5-year prospective natural history study. , 1998, Ophthalmology.

[11]  D M Snodderly,et al.  The macular pigment. I. Absorbance spectra, localization, and discrimination from other yellow pigments in primate retinas. , 1984, Investigative ophthalmology & visual science.

[12]  Dietrich Schweitzer,et al.  Impact of Macular Pigment on Fundus Autofluorescence Lifetimes. , 2015, Investigative ophthalmology & visual science.

[13]  S. Wolf,et al.  Fluorescence Lifetime Imaging in Stargardt Disease: Potential Marker for Disease Progression. , 2016, Investigative ophthalmology & visual science.

[14]  S. Dithmar.  [Macular hole. Survey and relevant surgical concepts]. , 2005, Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft.

[15]  P. Liao,et al.  Stereoscopic Atlas of Macular Diseases. Diagnosis and Treatment , 1987, The Yale Journal of Biology and Medicine.

[16]  A. Sommer,et al.  The cause-specific prevalence of visual impairment in an urban population. The Baltimore Eye Survey. , 1996, Ophthalmology.

[17]  M. la Cour,et al.  Macular holes: classification, epidemiology, natural history and treatment. , 2002, Acta ophthalmologica Scandinavica.

[18]  Sebastian Wolf,et al.  Autofluorescence Lifetimes in Geographic Atrophy in Patients With Age-Related Macular Degeneration. , 2016, Investigative ophthalmology & visual science.

[19]  Dietrich Schweitzer,et al.  Retinal fluorescence lifetime imaging ophthalmoscopy measures depend on the severity of Alzheimer's disease , 2015, Acta ophthalmologica.

[20]  U. Schmidt-Erfurth,et al.  Comparison of macular pigment in patients with age‐related macular degeneration and healthy control subjects – a study using spectral fundus reflectance , 2012, Acta ophthalmologica.

[21]  H. Ghoraba,et al.  TYPES OF MACULAR HOLES ENCOUNTERED DURING DIABETIC VITRECTOMY , 2002, Retina.

[22]  T. Sheidow,et al.  Macular hole secondary to retrobulbar needle perforation. , 1998, Retina.

[23]  S. Kishi,et al.  Posterior vitreous mobility delineated by tracking of optical coherence tomography images in eyes with idiopathic macular holes. , 2015, American journal of ophthalmology.

[24]  E. Chew,et al.  Clinical course of macular holes: the Eye Disease Case-Control Study. , 1999, Archives of ophthalmology.

[25]  David H Sliney,et al.  Maximum permissible exposures for ocular safety (ANSI 2000), with emphasis on ophthalmic devices. , 2007, Journal of the Optical Society of America. A, Optics, image science, and vision.

[26]  J. Jonas,et al.  Prevalence of full-thickness macular holes in urban and rural adult Chinese: the Beijing Eye Study. , 2006, American journal of ophthalmology.

[27]  M. Kass,et al.  Atlas of Clinical Ophthalmology , 1985 .

[28]  R. Wendel,et al.  Vitreous surgery for idiopathic macular holes. Results of a pilot study. , 1991, Archives of ophthalmology.

[29]  P. Bernstein,et al.  Retinal tubulin binds macular carotenoids. , 1997, Investigative ophthalmology & visual science.

[30]  S. Kishi,et al.  Tractional elevation of Henle's fiber layer in idiopathic macular holes. , 1995, American journal of ophthalmology.

[31]  D. Schweitzer,et al.  Towards metabolic mapping of the human retina , 2007, Microscopy research and technique.

[32]  J D Gass,et al.  Idiopathic senile macular hole. Its early stages and pathogenesis. , 1988, Archives of ophthalmology.

[33]  Gwénolé Quellec,et al.  Quantitative analysis of fluorescence lifetime measurements of the macula using the fluorescence lifetime imaging ophthalmoscope in healthy subjects. , 2014, Investigative ophthalmology & visual science.

[34]  D. Schweitzer,et al.  In vivo measurement of time-resolved autofluorescence at the human fundus. , 2004, Journal of biomedical optics.

[35]  T. Ciulla,et al.  Surgical treatment of a macular hole secondary to accidental laser burn. , 1997, Archives of ophthalmology.

[36]  L. Vijaya,et al.  Prevalence of idiopathic macular hole in adult rural and urban south Indian population , 2008, Clinical & experimental ophthalmology.

[37]  P. Pianka,et al.  Macular hole secondary to branch retinal vein occlusion diagnosed by Retinal Thickness Analyzer. , 2003, Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye.

[38]  Martin Hammer,et al.  Fluorescence lifetime imaging ophthalmoscopy in type 2 diabetic patients who have no signs of diabetic retinopathy , 2015, Journal of biomedical optics.

[39]  W. Smiddy,et al.  Bilaterality of idiopathic macular holes , 1996, Graefe's Archive for Clinical and Experimental Ophthalmology.

[40]  J. S. McCasland,et al.  Metabolic Mapping , 2000, Current protocols in neuroscience.

[41]  J. Gass,et al.  Müller cell cone, an overlooked part of the anatomy of the fovea centralis: hypotheses concerning its role in the pathogenesis of macular hole and foveomacualr retinoschisis. , 1999, Archives of ophthalmology.

[42]  Dietrich Schweitzer,et al.  FLIMX: A Software Package to Determine and Analyze the Fluorescence Lifetime in Time-Resolved Fluorescence Data from the Human Eye , 2015, PloS one.

[43]  P. Connell,et al.  MACULAR PIGMENT OPTICAL DENSITY IS LOWER IN TYPE 2 DIABETES, COMPARED WITH TYPE 1 DIABETES AND NORMAL CONTROLS , 2015, Retina.

[44]  D. Schweitzer,et al.  Time-resolved autofluorescence imaging of human donor retina tissue from donors with significant extramacular drusen. , 2012, Investigative ophthalmology & visual science.

[45]  J. Gass,et al.  XANTHIC SCOTOMA AND YELLOW FOVEOLAR SHADOW CAUSED BY A PSEUDO-OPERCULUM AFTER VITREOFOVEAL SEPARATION , 1992, Retina.