Advances in mesenchymal stem cell-mediated gene therapy for cancer

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[10]  M. Lacey,et al.  Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence , 2010, Breast Cancer Research and Treatment.

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[13]  P. Nelson,et al.  Targeting Tumor Stroma Using Engineered Mesenchymal Stem Cells Reduces the Growth of Pancreatic Carcinoma , 2009, Annals of surgery.

[14]  D. Davies,et al.  Mesenchymal stem cell delivery of TRAIL can eliminate metastatic cancer. , 2009, Cancer research.

[15]  H. Mizukami,et al.  Retroviral vector‐producing mesenchymal stem cells for targeted suicide cancer gene therapy , 2009, The journal of gene medicine.

[16]  A. Kate Sasser,et al.  Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression , 2009, PloS one.

[17]  Yao‐Hua Song,et al.  Tissue-resident stem cells promote breast cancer growth and metastasis. , 2009, Carcinogenesis.

[18]  Ralph Weissleder,et al.  Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy , 2009, Proceedings of the National Academy of Sciences.

[19]  B. Teicher,et al.  Human mesenchymal stem cells from bone marrow express tumor endothelial and stromal markers. , 2009, International journal of oncology.

[20]  D. Gisselsson,et al.  Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[21]  E. Kleinerman,et al.  Murine bone marrow–derived mesenchymal stem cells as vehicles for interleukin‐12 gene delivery into Ewing sarcoma tumors , 2009, Cancer.

[22]  Y. Sung,et al.  Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma. , 2008, Cancer research.

[23]  A. Rot,et al.  Murine Mesenchymal Stem Cells Exhibit a Restricted Repertoire of Functional Chemokine Receptors: Comparison with Human , 2008, PloS one.

[24]  Y. Bae,et al.  Mesenchymal stem cells derived from human adipose tissues favor tumor cell growth in vivo. , 2008, Stem cells and development.

[25]  D. Martineau,et al.  Neo-organoid of marrow mesenchymal stromal cells secreting interleukin-12 for breast cancer therapy. , 2008, Cancer research.

[26]  J. Mesirov,et al.  Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells. , 2008, Cancer research.

[27]  Peter R. Brink,et al.  Culturing of Human Mesenchymal Stem Cells as Three-dimensional Aggregates Induces Functional Expression of CXCR4 That Regulates Adhesion to Endothelial Cells* , 2008, Journal of Biological Chemistry.

[28]  A. Sbarbati,et al.  Mesenchymal stem cells share molecular signature with mesenchymal tumor cells and favor early tumor growth in syngeneic mice , 2008, Oncogene.

[29]  Yuquan Wei,et al.  A tumor-selective biotherapy with prolonged impact on established metastases based on cytokine gene-engineered MSCs. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

[30]  Zhili Xu,et al.  Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model , 2008, Cell Research.

[31]  G. Shaw,et al.  Mesenchymal stem cells expressing TRAIL lead to tumour growth inhibition in an experimental lung cancer model , 2008, Journal of cellular and molecular medicine.

[32]  J. Mathis,et al.  Mesenchymal Stem Cells Effectively Deliver an Oncolytic Adenovirus to Intracranial Glioma , 2008, Stem cells.

[33]  Shahin Rafii,et al.  Migratory neighbors and distant invaders: tumor-associated niche cells. , 2008, Genes & development.

[34]  M. Andreeff,et al.  The (in) auspicious role of mesenchymal stromal cells in cancer: be it friend or foe. , 2008, Cytotherapy.

[35]  W. Woodward,et al.  Tumor irradiation increases the recruitment of circulating mesenchymal stem cells into the tumor microenvironment. , 2007, Cancer research.

[36]  S. Grossman,et al.  Spontaneous expression of embryonic factors and p53 point mutations in aged mesenchymal stem cells: a model of age-related tumorigenesis in mice. , 2007, Cancer research.

[37]  Giselle Chamberlain,et al.  Concise Review: Mesenchymal Stem Cells: Their Phenotype, Differentiation Capacity, Immunological Features, and Potential for Homing , 2007, Stem cells.

[38]  Ross Tubo,et al.  Mesenchymal stem cells within tumour stroma promote breast cancer metastasis , 2007, Nature.

[39]  Paul G Scott,et al.  Mesenchymal Stem Cells Enhance Wound Healing Through Differentiation and Angiogenesis , 2007, Stem cells.

[40]  A. Cometa,et al.  Human bone marrow-derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms , 2010 .

[41]  M. Kerin,et al.  Monocyte Chemotactic Protein-1 Secreted by Primary Breast Tumors Stimulates Migration of Mesenchymal Stem Cells , 2007, Clinical Cancer Research.

[42]  Yaojiong Wu,et al.  Bone marrow‐derived stem cells in wound healing: a review , 2007, Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society.

[43]  K. Matsumoto,et al.  Targeted delivery of NK4 to multiple lung tumors by bone marrow-derived mesenchymal stem cells , 2007, Cancer Gene Therapy.

[44]  P. Lehenkari,et al.  Human mesenchymal stem cells lack tumor tropism but enhance the antitumor activity of oncolytic adenoviruses in orthotopic lung and breast tumors. , 2007, Human gene therapy.

[45]  M. Matúšková,et al.  Adipose tissue-derived human mesenchymal stem cells mediated prodrug cancer gene therapy. , 2007, Cancer research.

[46]  R. Zhao,et al.  Regulation of CXCR4 expression in human mesenchymal stem cells by cytokine treatment: role in homing efficiency in NOD/SCID mice. , 2007, Haematologica.

[47]  M. Endres,et al.  Towards in situ tissue repair: Human mesenchymal stem cells express chemokine receptors CXCR1, CXCR2 and CCR2, and migrate upon stimulation with CXCL8 but not CCL2 , 2007, Journal of cellular biochemistry.

[48]  M. Kay,et al.  Sarcoma Derived from Cultured Mesenchymal Stem Cells , 2007, Stem cells.

[49]  J. Mathis,et al.  Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma , 2007, Breast Cancer Research and Treatment.

[50]  E. Seifried,et al.  Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells. , 2006, Blood.

[51]  G. Semenza,et al.  Spontaneous transformation of cultured mouse bone marrow-derived stromal cells. , 2006, Cancer research.

[52]  F. Djouad,et al.  Earlier Onset of Syngeneic Tumors in the Presence of Mesenchymal Stem Cells , 2006, Transplantation.

[53]  Yongchang Chen,et al.  Mesenchymal stem cells derived from bone marrow favor tumor cell growth in vivo. , 2006, Experimental and molecular pathology.

[54]  M. Raffeld,et al.  Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma , 2006, The Journal of experimental medicine.

[55]  I. Ghiran,et al.  Human Bone Marrow Stromal Cells Express a Distinct Set of Biologically Functional Chemokine Receptors , 2006, Stem cells.

[56]  Baojin Fu,et al.  Accumulated Chromosomal Instability in Murine Bone Marrow Mesenchymal Stem Cells Leads to Malignant Transformation , 2006, Stem cells.

[57]  D. Curiel,et al.  Mesenchymal progenitor cells as cellular vehicles for delivery of oncolytic adenoviruses , 2006, Molecular Cancer Therapeutics.

[58]  D. Prockop,et al.  Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. , 2006, Cytotherapy.

[59]  M. Reitz,et al.  Human mesenchymal stem cells exert potent antitumorigenic eff ects in a model of Kaposi’s sarcoma , 2006 .

[60]  Simon C Watkins,et al.  Epidermal growth factor receptor-transfected bone marrow stromal cells exhibit enhanced migratory response and therapeutic potential against murine brain tumors , 2005, Cancer Gene Therapy.

[61]  E. Bonifacio,et al.  Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. , 2005, Blood.

[62]  P. Nelson,et al.  Human adult CD34- progenitor cells functionally express the chemokine receptors CCR1, CCR4, CCR7, CXCR5, and CCR10 but not CXCR4. , 2005, Stem cells and development.

[63]  M. Andreeff,et al.  Human bone marrow-derived mesenchymal stem cells in the treatment of gliomas. , 2005, Cancer research.

[64]  J. Cigudosa,et al.  Spontaneous human adult stem cell transformation. , 2005, Cancer research.

[65]  D. Huso,et al.  Outgrowth of a transformed cell population derived from normal human BM mesenchymal stem cell culture. , 2005, Cytotherapy.

[66]  M. Andreeff,et al.  Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agents. , 2004, Journal of the National Cancer Institute.

[67]  I. Bellantuono,et al.  A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow. , 2004, Blood.

[68]  L. Lejeune,et al.  Marrow stromal cells for interleukin-2 delivery in cancer immunotherapy. , 2004, Human gene therapy.

[69]  H. Tsuda,et al.  Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model , 2004, Gene Therapy.

[70]  F. Barry,et al.  Mesenchymal stem cells: clinical applications and biological characterization. , 2004, The international journal of biochemistry & cell biology.

[71]  M. Lindvall,et al.  Mesenchymal progenitor cell-mediated inhibition of tumor growth in vivo and in vitro in gelatin matrix. , 2003, Experimental and molecular pathology.

[72]  F. Djouad,et al.  Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals. , 2003, Blood.

[73]  D. Curiel,et al.  Approaches to Utilize Mesenchymal Progenitor Cells as Cellular Vehicles , 2003, Stem cells.

[74]  O. Ringdén,et al.  Mesenchymal Stem Cells Inhibit and Stimulate Mixed Lymphocyte Cultures and Mitogenic Responses Independently of the Major Histocompatibility Complex , 2003, Scandinavian journal of immunology.

[75]  L. Coussens,et al.  Inflammation and cancer , 2002, Nature.

[76]  M. Andreeff,et al.  Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumors. , 2002, Cancer research.

[77]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[78]  G. Maestroni,et al.  Factor(s) from nonmacrophage bone marrow stromal cells inhibit Lewis lung carcinoma and B16 melanoma growth in mice , 1999, Cellular and Molecular Life Sciences CMLS.

[79]  H. Dvorak.  Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. , 1986, The New England journal of medicine.