Human Fatty Liver Disease: Old Questions and New Insights
暂无分享,去创建一个
[1] Jeffrey B. Schwimmer,et al. Prevalence of Fatty Liver in Children and Adolescents , 2006, Pediatrics.
[2] J. Goldstein,et al. Selective versus total insulin resistance: a pathogenic paradox. , 2008, Cell metabolism.
[3] B. Neuschwander‐Tetri,et al. Pioglitazone, vitamin E, or placebo for nonalcoholic steatohepatitis. , 2010, The New England journal of medicine.
[4] N. Schork,et al. Heritability of nonalcoholic fatty liver disease. , 2009, Gastroenterology.
[5] Jonathan C. Cohen,et al. A feed-forward loop amplifies nutritional regulation of PNPLA3 , 2010, Proceedings of the National Academy of Sciences.
[6] S. Harrison,et al. Nonalcoholic fatty liver disease and hepatocellular carcinoma: A weighty connection , 2010, Hepatology.
[7] J. Schneider,et al. "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis. , 2005, Cell metabolism.
[8] A. Feldstein,et al. Lipotoxicity in nonalcoholic fatty liver disease: not all lipids are created equal , 2009, Expert review of gastroenterology & hepatology.
[9] Frank Eisenhaber,et al. Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase , 2004, Science.
[10] R. Coleman,et al. Hepatic triacylglycerol accumulation and insulin resistance This work was supported by National Institutes of Health Grants DK56598, DK59935, and DK56350. Published, JLR Papers in Press, November 6, 2008. , 2009, Journal of Lipid Research.
[11] M. Welte. Proteins under new management: lipid droplets deliver. , 2007, Trends in cell biology.
[12] J. George,et al. Animal models of nonalcoholic fatty liver disease , 2011, Nature Reviews Gastroenterology &Hepatology.
[13] L. N. Valenti,et al. Risk of severe liver disease in nonalcoholic fatty liver disease with normal aminotransferase levels: A role for insulin resistance and diabetes , 2008, Hepatology.
[14] S. Caldwell,et al. Nonalcoholic steatohepatitis and cryptogenic cirrhosis within kindreds. , 2000, The American journal of medicine.
[15] Joseph L Goldstein,et al. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. , 2002, The Journal of clinical investigation.
[16] Jonathan C. Cohen,et al. Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity , 2004, Hepatology.
[17] D. Reijngoud,et al. Increased de novo Lipogenesis and Delayed Conversion of Large VLDL into Intermediate Density Lipoprotein Particles Contribute to Hyperlipidemia in Glycogen Storage Disease Type 1a , 2008, Pediatric Research.
[18] M. Kumari,et al. Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome[S] , 2011, Journal of Lipid Research.
[19] P. Fontes,et al. Recurrent disease following liver transplantation for nonalcoholic steatohepatitis cirrhosis , 2009, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.
[20] Jonathan C. Cohen,et al. Dissociation Between APOC3 Variants, Hepatic Triglyceride Content and Insulin Resistance , 2011, Hepatology.
[21] S. Grundy,et al. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. , 2005, American journal of physiology. Endocrinology and metabolism.
[22] S. Caldwell,et al. Systematic review of risk factors for fibrosis progression in non-alcoholic steatohepatitis. , 2009, Journal of hepatology.
[23] S. Caldwell,et al. Epidemiology and natural history of non-alcoholic steatohepatitis. , 2009, Clinics in liver disease.
[24] John T. Melchior,et al. CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance[S] , 2010, Journal of Lipid Research.
[25] A. Kotronen,et al. Unravelling the pathogenesis of fatty liver disease: patatin-like phospholipase domain-containing 3 protein , 2010, Current opinion in lipidology.
[26] J. Burnett,et al. Genetic determinants of hepatic steatosis in man , 2011, Journal of Lipid Research.
[27] Alexander Pertsemlidis,et al. Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease , 2008, Nature Genetics.
[28] H. Tilg. The Role of Cytokines in Non-Alcoholic Fatty Liver Disease , 2010, Digestive Diseases.
[29] D. Yablonskiy,et al. Fatty liver in familial hypobetalipoproteinemia: roles of the APOB defects, intra-abdominal adipose tissue, and insulin sensitivity. , 2004, Journal of lipid research.
[30] A. Shapiro,et al. Prevalence of hepatic steatosis after islet transplantation and its relation to graft function. , 2004, Diabetes.
[31] A. Feldstein,et al. Novel Insights into the Pathophysiology of Nonalcoholic Fatty Liver Disease , 2010, Seminars in liver disease.
[32] J. George,et al. Fitness versus fatness: Moving beyond weight loss in nonalcoholic fatty liver disease , 2010, Hepatology.
[33] K. Petersen,et al. Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease. , 2010, The New England journal of medicine.
[34] B. Chang,et al. Patatin‐like phospholipase domain‐containing 3/adiponutrin deficiency in mice is not associated with fatty liver disease , 2010, Hepatology.
[35] S. Sookoian,et al. A nonsynonymous gene variant in the adiponutrin gene is associated with nonalcoholic fatty liver disease severity , 2009, Journal of Lipid Research.
[36] J. Cercueil,et al. Lack of an association between an apolipoprotein C3 genetic variant and the liver fat content in patients with type 2 diabetes , 2011, Hepatology.
[37] Shijie Li,et al. Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis , 2010, Proceedings of the National Academy of Sciences.
[38] G. Hotamisligil,et al. Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease , 2010, Cell.
[39] David Kershenobich,et al. Variant in PNPLA3 is associated with alcoholic liver disease , 2010, Nature Genetics.
[40] T. Redgrave. Formation of cholesteryl ester-rich particulate lipid during metabolism of chylomicrons. , 1970, The Journal of clinical investigation.
[41] Claudio Cobelli,et al. Increased prevalence of insulin resistance and nonalcoholic fatty liver disease in Asian-Indian men , 2006, Proceedings of the National Academy of Sciences.
[42] K. Kasturi,et al. Effect of bariatric surgery on nonalcoholic fatty liver disease: systematic review and meta-analysis. , 2008, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
[43] Luigi Ferrucci,et al. Population-based genome-wide association studies reveal six loci influencing plasma levels of liver enzymes. , 2008, American journal of human genetics.
[44] S. O’Rahilly,et al. Postreceptor insulin resistance contributes to human dyslipidemia and hepatic steatosis. , 2009, The Journal of clinical investigation.
[45] L. Tappy,et al. Metabolic effects of fructose and the worldwide increase in obesity. , 2010, Physiological reviews.
[46] J. Repa,et al. Carbohydrate response element binding protein, ChREBP, a transcription factor coupling hepatic glucose utilization and lipid synthesis. , 2006, Cell metabolism.
[47] Udo Hoffmann,et al. Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits , 2011, PLoS genetics.
[48] Nick V. Grishin,et al. A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis , 2009, The Journal of Biological Chemistry.
[49] J. Jessurun,et al. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. , 2005, The Journal of clinical investigation.
[50] T. Saheki,et al. Citrin deficiency as a cause of chronic liver disorder mimicking non-alcoholic fatty liver disease. , 2008, Journal of hepatology.