Mitochondrial dysfunction promotes the necroptosis of Purkinje cells in the cerebellum of acrylamide-exposed rats.

[1]  Hong Yan,et al.  Effect of long-term exposure to acrylamide on endoplasmic reticulum stress and autophagy in rat cerebellum. , 2021, Ecotoxicology and environmental safety.

[2]  Wang Minghua,et al.  Rosmarinic acid attenuates acrylamide induced apoptosis of BRL-3A cells by inhibiting oxidative stress and endoplasmic reticulum stress. , 2021, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[3]  Shenmin Zhang,et al.  ROS-Mediated Necroptosis Is Involved in Iron Overload-Induced Osteoblastic Cell Death , 2020, Oxidative medicine and cellular longevity.

[4]  Yufan Liu,et al.  Chronic acrylamide exposure induced glia cell activation, NLRP3 infl-ammasome upregulation and cognitive impairment. , 2020, Toxicology and applied pharmacology.

[5]  F. Saleh,et al.  A Review on Acrylamide in Food: Occurrence, Toxicity, and Mitigation Strategies , 2020, International journal of toxicology.

[6]  Yuan Luo,et al.  NLRP3 inflammasome inhibition attenuates subacute neurotoxicity induced by acrylamide in vitro and in vivo. , 2020, Toxicology.

[7]  N. Chen,et al.  Dynamin-related protein 1: A protein critical for mitochondrial fission, mitophagy, and neuronal death in Parkinson's disease. , 2019, Pharmacological research.

[8]  Zhenyu Shen,et al.  Mitophagy protects against acetaminophen-induced acute liver injury in mice through inhibiting NLRP3 inflammasome activation. , 2019, Biochemical pharmacology.

[9]  Yuanxiang Jin,et al.  Autophagy protects murine macrophages from β-cypermethrin-induced mitochondrial dysfunction and cytotoxicity via the reduction of oxidation stress. , 2019, Environmental pollution.

[10]  Salim S. Al-Rejaie,et al.  Can acetaminophen/dimethyl sulfoxide formulation prevent accidental and intentional acetaminophen hepatotoxicity? , 2019, Drug development research.

[11]  T. Sakurai,et al.  Role of microglial activation and neuroinflammation in neurotoxicity of acrylamide in vivo and in vitro , 2019, Archives of Toxicology.

[12]  Haitao Wang,et al.  Inhibition of Phosphodiesterase 4 by FCPR03 Alleviates Chronic Unpredictable Mild Stress-Induced Depressive-Like Behaviors and Prevents Dendritic Spine Loss in Mice Hippocampi , 2018, The international journal of neuropsychopharmacology.

[13]  Y. El-Sayed,et al.  Apoptosis and astrogliosis perturbations and expression of regulatory inflammatory factors and neurotransmitters in acrylamide-induced neurotoxicity under ω3 fatty acids protection in rats. , 2019, Neurotoxicology.

[14]  Junying Yuan,et al.  Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases , 2018, Nature Reviews Neuroscience.

[15]  Xiaosong Hu,et al.  Acrylamide-induced neurotoxicity in primary astrocytes and microglia: Roles of the Nrf2-ARE and NF-κB pathways. , 2017, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[16]  D. Green,et al.  Necroptosis in development, inflammation and disease , 2016, Nature Reviews Molecular Cell Biology.

[17]  R. LoPachin,et al.  Joint toxic effects of the type-2 alkene electrophiles. , 2016, Chemico-biological interactions.

[18]  D. Green,et al.  Programmed necrosis in inflammation: Toward identification of the effector molecules , 2016, Science.

[19]  S. Fulda,et al.  Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death , 2015, Oncogene.

[20]  Dorian B. McGavern,et al.  Microglia development and function. , 2014, Annual review of immunology.

[21]  Sang Gyun Kim,et al.  Rapamycin: one drug, many effects. , 2014, Cell metabolism.

[22]  Wen-jie Zheng,et al.  Selective cellular uptake and induction of apoptosis of cancer-targeted selenium nanoparticles. , 2013, Biomaterials.

[23]  V. Perry,et al.  Microglia and macrophages of the central nervous system: the contribution of microglia priming and systemic inflammation to chronic neurodegeneration , 2013, Seminars in Immunopathology.

[24]  Muralidhara,et al.  Neuroprotective Efficacy of Eugenol and Isoeugenol in Acrylamide-Induced Neuropathy in rats: Behavioral and Biochemical evidence , 2012, Neurochemical Research.

[25]  Jiahuai Han,et al.  New components of the necroptotic pathway , 2012, Protein & Cell.

[26]  R. LoPachin,et al.  Molecular Mechanism of Acrylamide Neurotoxicity: Lessons Learned from Organic Chemistry , 2012, Environmental health perspectives.

[27]  Xiaodong Wang,et al.  The Mitochondrial Phosphatase PGAM5 Functions at the Convergence Point of Multiple Necrotic Death Pathways , 2012, Cell.

[28]  A. Fernando,et al.  Structural and ultrastructural evidence of neurotoxic effects of fried potato chips on rat postnatal development. , 2011, Nutrition.

[29]  Nam-Ho Kim,et al.  Mitogen-Activated Protein Kinases and Reactive Oxygen Species: How Can ROS Activate MAPK Pathways? , 2011, Journal of signal transduction.

[30]  T. Vanden Berghe,et al.  Programmed necrosis from molecules to health and disease. , 2011, International review of cell and molecular biology.

[31]  Junying Yuan,et al.  Necroptosis as an alternative form of programmed cell death. , 2010, Current opinion in cell biology.

[32]  Wim Declercq,et al.  Tumor necrosis factor-mediated cell death: to break or to burst, that’s the question , 2010, Cellular and Molecular Life Sciences.

[33]  S. Dunnett,et al.  Comparison of incremental and accelerating protocols of the rotarod test for the assessment of motor deficits in the 6-OHDA model , 2006, Journal of Neuroscience Methods.

[34]  N. Ilbäck,et al.  Acrylamide tissue distribution and genotoxic effects in a common viral infection in mice. , 2005, Toxicology.

[35]  R. LoPachin,et al.  The changing view of acrylamide neurotoxicity. , 2004, Neurotoxicology.

[36]  H. Sjöholm,et al.  Effects on the peripheral nervous system of tunnel workers exposed to acrylamide and N-methylolacrylamide. , 2004, Scandinavian journal of work, environment & health.

[37]  J. Larsen,et al.  The volume of Purkinje cells decreases in the cerebellum of acrylamide — intoxicated rats, but no cells are lost , 2004, Acta Neuropathologica.

[38]  J. Cavanagh,et al.  Selective loss of Purkinje cells from the rat cerebellum caused by acrylamide and the responses ofβ-glucuronidase andβ-galactosidase , 2004, Acta Neuropathologica.

[39]  M. Friedman.  Chemistry, biochemistry, and safety of acrylamide. A review. , 2003, Journal of agricultural and food chemistry.

[40]  C. Balaban,et al.  Acrylamide axonopathy revisited. , 2003, Toxicology and applied pharmacology.

[41]  C. Balaban,et al.  Acrylamide neuropathy. I. Spatiotemporal characteristics of nerve cell damage in rat cerebellum. , 2002, Neurotoxicology.

[42]  Eden Tareke,et al.  Analysis of acrylamide, a carcinogen formed in heated foodstuffs. , 2002, Journal of agricultural and food chemistry.

[43]  K. Hellenäs,et al.  Analysis of acrylamide in cooked foods by liquid chromatography tandem mass spectrometry. , 2002, The Analyst.

[44]  S. Das,et al.  Neurological evaluation of toxic axonopathies in rats: acrylamide and 2,5-hexanedione. , 2002, Neurotoxicology.

[45]  Carlos Portera-Cailliau,et al.  Neurodegeneration in Excitotoxicity, Global Cerebral Ischemia, and Target Deprivation: A Perspective on the Contributions of Apoptosis and Necrosis , 1998, Brain Research Bulletin.

[46]  L. Costa,et al.  Evaluation of the neurotoxicity of glycidamide, an epoxide metabolite of acrylamide: behavioral, neurochemical and morphological studies. , 1995, Toxicology.

[47]  C. Sotelo,et al.  Target neuron controls the integrity of afferent axon phenotype: a study on the Purkinje cell-climbing fiber system in cerebellar mutant mice , 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[48]  K. Reuhl,et al.  Synergistic neurotoxic effects of styrene oxide and acrylamide: glutathione-independent necrosis of cerebellar granule cells. , 1993, Toxicology and applied pharmacology.

[49]  D. Anthony,et al.  Comparison of subchronic neurotoxicity of 2-hydroxyethyl acrylate and acrylamide in rats. , 1992, Fundamental and applied toxicology : official journal of the Society of Toxicology.

[50]  E. Faustman,et al.  Comparative studies on the neuro- and reproductive toxicity of acrylamide and its epoxide metabolite glycidamide in the rat. , 1992, Neurotoxicology.

[51]  F. Oehme,et al.  Acrylamide and Polyacrylamide: A Review of Production, Use, Environmental Fate and Neurotoxicity , 1991, Reviews on environmental health.

[52]  Z. Zhang,et al.  Neurological and electroneuromyographic assessment of the adverse effects of acrylamide on occupationally exposed workers. , 1989, Scandinavian journal of work, environment & health.

[53]  J. Cavanagh,et al.  Ultrastructural features of the Purkinje cell damage caused by acrylamide in the rat: a new phenomenon in cellular neuropathology , 1983, Journal of neurocytology.

[54]  George Paxinos,et al.  AChE-stained horizontal sections of the rat brain in stereotaxic coordinates , 1980, Journal of Neuroscience Methods.

[55]  P. M. Edwards,et al.  A simple, sensitive, and objective method for early assessment of acrylamide neuropathy in rats. , 1977, Toxicology and applied pharmacology.

[56]  P. Spencer,et al.  Nervous system degeneration produced by acrylamide monomer. , 1975, Environmental health perspectives.