Linkage analysis of obesity phenotypes in pre- and post-menopausal women from a United States mid-western population

[1]  Jason H. Moore,et al.  Missing heritability and strategies for finding the underlying causes of complex disease , 2010, Nature Reviews Genetics.

[2]  K. Flegal,et al.  Prevalence and trends in obesity among US adults, 1999-2008. , 2010, JAMA.

[3]  P. Conn,et al.  Metabotropic glutamate receptors: physiology, pharmacology, and disease. , 2010, Annual review of pharmacology and toxicology.

[4]  Laura J. Scott,et al.  Edinburgh Research Explorer Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution , 2022 .

[5]  Suzette J. Bielinski,et al.  NRXN3 Is a Novel Locus for Waist Circumference: A Genome-Wide Association Study from the CHARGE Consortium , 2009, PLoS genetics.

[6]  Olaf B. Paulson,et al.  Brain serotonin 2A receptor binding: Relations to body mass index, tobacco and alcohol use , 2009, NeuroImage.

[7]  J. Després,et al.  Visceral Obesity: The Link Among Inflammation, Hypertension, and Cardiovascular Disease , 2009, Hypertension.

[8]  T. Hansen,et al.  Common nonsynonymous variants in PCSK1 confer risk of obesity , 2008, Nature Genetics.

[9]  Philippe Froguel,et al.  Genome-wide association scans identified CTNNBL1 as a novel gene for obesity. , 2008, Human molecular genetics.

[10]  Philippe Froguel,et al.  Common genetic variation near MC4R is associated with waist circumference and insulin resistance , 2008, Nature Genetics.

[11]  W. G. Hill,et al.  Heritability in the genomics era — concepts and misconceptions , 2008, Nature Reviews Genetics.

[12]  S. Christian,et al.  Disruption of contactin 4 in three subjects with autism spectrum disorder , 2008, Journal of Medical Genetics.

[13]  R. Wildman,et al.  Change in adipocytokines and ghrelin with menopause. , 2008, Maturitas.

[14]  M. Travis,et al.  Long-term estrogen therapy and 5-HT2A receptor binding in postmenopausal women; a single photon emission tomography (SPET) study , 2008, Hormones and Behavior.

[15]  Beverley Balkau,et al.  Variation in FTO contributes to childhood obesity and severe adult obesity , 2007, Nature Genetics.

[16]  M. Yosef,et al.  Changes in body composition in women over six years at midlife: ovarian and chronological aging. , 2007, The Journal of clinical endocrinology and metabolism.

[17]  Arya M. Sharma,et al.  Peroxisome Proliferator-Activated Receptor γ and Adipose Tissue—Understanding Obesity-Related Changes in Regulation of Lipid and Glucose Metabolism , 2007 .

[18]  D. Nutt,et al.  Tryptophan metabolism in the central nervous system: medical implications , 2006, Expert Reviews in Molecular Medicine.

[19]  J. Nahon.  The melanocortins and melanin-concentrating hormone in the central regulation of feeding behavior and energy homeostasis. , 2006, Comptes rendus biologies.

[20]  R. Cantor,et al.  Longitudinal differences in familial combined hyperlipidemia quantitative trait loci. , 2006, Arteriosclerosis, thrombosis, and vascular biology.

[21]  F. Hu,et al.  A Common Genetic Variant Is Associated with Adult and Childhood Obesity , 2006, Science.

[22]  S. Benoit,et al.  Gut hormones ghrelin, PYY and GLP-1 in the regulation of energy balance and metabolism , 2006, Endocrine.

[23]  G. Bray,et al.  Epidemiology, trends, and morbidities of obesity and the metabolic syndrome , 2006, Endocrine.

[24]  Majid Ezzati,et al.  Causes of cancer in the world: comparative risk assessment of nine behavioural and environmental risk factors , 2005, The Lancet.

[25]  T. Sellers.  Statistical Methods in Genetic Epidemiology , 2005 .

[26]  Claude Bouchard,et al.  The Human Obesity Gene Map: The 2005 Update , 2006, Obesity.

[27]  L. Dennerstein,et al.  The menopausal transition: a 9-year prospective population-based study. The Melbourne Women's Midlife Health Project , 2004, Climacteric : the journal of the International Menopause Society.

[28]  E. Calle,et al.  Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms , 2004, Nature Reviews Cancer.

[29]  J. Lovejoy.  The menopause and obesity. , 2003, Primary care.

[30]  M. C. Carr,et al.  The emergence of the metabolic syndrome with menopause. , 2003, The Journal of clinical endocrinology and metabolism.

[31]  Ralph B D'Agostino,et al.  Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study. , 2002, American journal of human genetics.

[32]  K. Flegal,et al.  Prevalence and trends in obesity among US adults, 1999-2000. , 2002, JAMA.

[33]  M. Rendell,et al.  Effects of Estrogen Replacement Therapy on Abdominal Fat Compartments as Related to Glucose and Lipid Metabolism in Early Postmenopausal Women , 2002, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

[34]  C. Björkelund,et al.  Larger hip circumference independently predicts health and longevity in a Swedish female cohort. , 2001, Obesity research.

[35]  L. Pérusse,et al.  Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study. , 2001, The American journal of clinical nutrition.

[36]  C. Bethea,et al.  Estrogen receptor beta (ERbeta) mRNA and protein in serotonin neurons of macaques. , 2001, Brain research. Molecular brain research.

[37]  D. Grabrick,et al.  Evidence for a major gene influence on abdominal fat distribution: The Minnesota breast cancer family study , 2001, Genetic epidemiology.

[38]  B. Wajchenberg.  Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. , 2000, Endocrine reviews.

[39]  T. Sellers,et al.  Associations of general and abdominal obesity with multiple health outcomes in older women: the Iowa Women's Health Study. , 2000, Archives of internal medicine.

[40]  S. Iturria,et al.  An EM algorithm for obtaining maximum likelihood estimates in the multi-phenotype variance components linkage model. , 2000, Annals of human genetics.

[41]  M. Neale,et al.  Genetic and Environmental Factors in Relative Body Weight and Human Adiposity , 1997, Behavior genetics.

[42]  M. Ramakrishnan,et al.  Neuritin: a gene induced by neural activity and neurotrophins that promotes neuritogenesis. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[43]  T. Spector,et al.  Independent genetic factors determine the amount and distribution of fat in women after the menopause. , 1997, The Journal of clinical endocrinology and metabolism.

[44]  T. Sellers,et al.  Validation study of self-reported measures of fat distribution. , 1996, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[45]  K Lange,et al.  Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. , 1996, American journal of human genetics.

[46]  E. Lander,et al.  Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results , 1995, Nature Genetics.

[47]  N. Rojansky,et al.  Estrogen augments serotonergic activity in postmenopausal women , 1995, Biological Psychiatry.

[48]  P. Björntorp,et al.  Neuroendocrine abnormalities in human obesity. , 1995, Metabolism: clinical and experimental.

[49]  C. Christiansen,et al.  Postmenopausal hormone replacement therapy prevents central distribution of body fat after menopause. , 1991, Metabolism: clinical and experimental.

[50]  K. Lange,et al.  Extensions to pedigree analysis. IV. Covariance components models for multivariate traits. , 1983, American journal of medical genetics.

[51]  S. Leibowitz.  The Role of Serotonin in Eating Disorders , 2012, Drugs.

[52]  Christian Gieger,et al.  Six new loci associated with body mass index highlight a neuronal influence on body weight regulation , 2009, Nature Genetics.

[53]  Ellen Kampman,et al.  Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity , 2009, Nature Genetics.

[54]  Arya M. Sharma,et al.  Review: Peroxisome proliferator-activated receptor gamma and adipose tissue--understanding obesity-related changes in regulation of lipid and glucose metabolism. , 2007, The Journal of clinical endocrinology and metabolism.

[55]  Yi Wang,et al.  BMC Medical Genetics , 2007 .

[56]  S. Benoit,et al.  Gut hormones ghrelin, PYY, and GLP-1 in the regulation of energy balance [corrected] and metabolism. , 2006, Endocrine.

[57]  S. Souza,et al.  Estrogen Regulation of Adiposity and Fuel Partitioning EVIDENCE OF GENOMIC AND NON-GENOMIC REGULATION OF LIPOGENIC AND OXIDATIVE PATHWAYS * , 2005 .

[58]  M. de Andrade,et al.  Assessing linkage on chromosome 5 using components of variance approach: Univariate versus multivariate , 1997, Genetic epidemiology.

[59]  T. Sellers,et al.  Epidemiologic and genetic follo‐up study of 544 Minnesota breast cancer families: Design and methods , 1995, Genetic epidemiology.

[60]  Robert C. Elston,et al.  Extensions to Pedigree Analysis , 1975 .