Polymorphisms in the DNA repair gene XRCC1 and age-related disease

[1]  D. Noh,et al.  XRCC1 genetic polymorphism and breast cancer risk. , 2002, Pharmacogenetics.

[2]  C. Relton,et al.  Polymorphisms of the DNA repair gene XRCC1 and the frequency of somatic mutations at the glycophorin A locus in newborns. , 2002, Mutation research.

[3]  K. Caldecott,et al.  Central Role for the XRCC1 BRCT I Domain in Mammalian DNA Single-Strand Break Repair , 2002, Molecular and Cellular Biology.

[4]  S. London,et al.  Genetic polymorphism of XRCC1 and lung cancer risk among African-Americans and Caucasians. , 2001, Lung cancer.

[5]  I. Hickson,et al.  XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein–protein interactions , 2001, The EMBO journal.

[6]  S. Groshen,et al.  A polymorphism of the XRCC1 gene predicts for response to platinum based treatment in advanced colorectal cancer. , 2001, Anticancer research.

[7]  H. Mohrenweiser,et al.  Amino acid substitution variants of APE1 and XRCC1 genes associated with ionizing radiation sensitivity. , 2001, Carcinogenesis.

[8]  E J Duell,et al.  Polymorphisms in the DNA repair gene XRCC1 and breast cancer. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[9]  M. Tockman,et al.  Polymorphisms of the DNA repair gene XRCC1 and lung cancer risk. , 2001, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[10]  M. Weinfeld,et al.  XRCC1 Stimulates Human Polynucleotide Kinase Activity at Damaged DNA Termini and Accelerates DNA Single-Strand Break Repair , 2001, Cell.

[11]  F. Gilliland,et al.  The XRCC1 399 glutamine allele is a risk factor for adenocarcinoma of the lung. , 2001, Mutation research.

[12]  K. Caldecott,et al.  Mutation of a BRCT domain selectively disrupts DNA single-strand break repair in noncycling Chinese hamster ovary cells. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[13]  W. Evans,et al.  Aged human muscle demonstrates an altered gene expression profile consistent with an impaired response to exercise , 2000, Mechanisms of Ageing and Development.

[14]  S. Z. Abdel‐Rahman,et al.  The 399Gln polymorphism in the DNA repair gene XRCC1 modulates the genotoxic response induced in human lymphocytes by the tobacco-specific nitrosamine NNK. , 2000, Cancer letters.

[15]  B. Levin,et al.  Inheritance of the 194Trp and the 399Gln variant alleles of the DNA repair gene XRCC1 are associated with increased risk of early-onset colorectal carcinoma in Egypt. , 2000, Cancer letters.

[16]  A. Harris,et al.  A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer. , 2000, Cancer research.

[17]  M. West,et al.  XRCC1 keeps DNA from getting stranded. , 2000, Mutation research.

[18]  M. Flannery,et al.  Requirement for the Xrcc1 DNA base excision repair gene during early mouse development. , 1999, Developmental biology.

[19]  L. Brooks,et al.  A DNA polymorphism discovery resource for research on human genetic variation. , 1998, Genome research.

[20]  M. Masson,et al.  XRCC1 Is Specifically Associated with Poly(ADP-Ribose) Polymerase and Negatively Regulates Its Activity following DNA Damage , 1998, Molecular and Cellular Biology.

[21]  I. M. Jones,et al.  Nonconservative amino acid substitution variants exist at polymorphic frequency in DNA repair genes in healthy humans. , 1998, Cancer research.

[22]  H. Mohrenweiser,et al.  Mutations in hamster single-strand break repair gene XRCC1 causing defective DNA repair. , 1998, Nucleic acids research.

[23]  B. Ames,et al.  Oxidative Decay of DNA* , 1997, The Journal of Biological Chemistry.

[24]  K. Caldecott,et al.  XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro. , 1996, Nucleic acids research.

[25]  L. Thompson,et al.  An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III , 1994, Molecular and cellular biology.

[26]  T. Lindahl.  Instability and decay of the primary structure of DNA , 1993, Nature.

[27]  L. Thompson,et al.  Construction of human XRCC1 minigenes that fully correct the CHO DNA repair mutant EM9. , 1992, Nucleic acids research.

[28]  M. Karagas,et al.  The XRCC1 Arg399Gln polymorphism, sunburn, and non-melanoma skin cancer: evidence of gene-environment interaction. , 2002, Cancer research.

[29]  C. H. Kim,et al.  Polymorphism of the DNA repair gene XRCC1 and risk of primary lung cancer. , 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.