Inmunología del absceso hepático amebiano

La infeccion por el parasito Entamoeba histolytica es causa de disenteria y absceso hepatico amebianos, enfermedades asociadas con alta morbi-mortalidad. En el caso de la amebiosis hepatica, el papel de la inmunidad humoral en la proteccion no ha sido del todo establecido pero tiene importancia en estudios seroepidemiologicos y metodos diagnosticos. La inmunidad celular es importante para el control de la infeccion y desarrollo de inmunidad protectora luego de amebiosis invasiva. Las tecnicas de genetica molecular y los nuevos modelos de experimentacion han ensenado mucho acerca de la patogenesis de la amebiosis, su entendimiento adecuado junto con el conocimiento de la biologia molecular y genetica del parasito y los mecanismos inmunes del huesped permitira no solo el desarrollo de nuevas opciones diagnosticas y de tratamiento sino tambien de una vacuna efectiva y segura para eliminar la enfermedad.

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