Collagen-Based Photoactive Agent for Tissue Bonding.

Using a combination of methacrylated collagen and the photosensitizer rose Bengal, a new light-activated biomimetic material for tissue sutureless bonding was developed. This formulation was cross-linked using green light. In vivo tests in mice demonstrate the suitability of the material for sutureless wound closure.

[1]  Ali Khademhosseini,et al.  Bioconjugated Hydrogels for Tissue Engineering and Regenerative Medicine. , 2015, Bioconjugate chemistry.

[2]  I. Chapple,et al.  Biomaterials for promoting periodontal regeneration in human intrabony defects: a systematic review. , 2015, Periodontology 2000.

[3]  I. Kochevar,et al.  Light‐activated sealing of skin wounds , 2015, Lasers in surgery and medicine.

[4]  Sara Ferraris,et al.  Biomaterials for orbital implants and ocular prostheses: overview and future prospects. , 2014, Acta biomaterialia.

[5]  J. Scaiano,et al.  Impact of Dye‐Protein Interaction and Silver Nanoparticles on Rose Bengal Photophysical Behavior and Protein Photocrosslinking , 2013, Photochemistry and photobiology.

[6]  Hongbo Zeng,et al.  Understanding the effect of secondary structure on molecular interactions of poly-L-lysine with different substrates by SFA. , 2013, Biomacromolecules.

[7]  Jiang Wang,et al.  The chemistry of amine radical cations produced by visible light photoredox catalysis , 2013, Beilstein journal of organic chemistry.

[8]  B. Liedberg,et al.  Epoxy Cross-Linked Collagen and Collagen-Laminin Peptide Hydrogels as Corneal Substitutes , 2013, Journal of functional biomaterials.

[9]  S. Melki,et al.  Collagen cross-linking using rose bengal and green light to increase corneal stiffness. , 2013, Investigative ophthalmology & visual science.

[10]  Molly M. Stevens,et al.  Designing Regenerative Biomaterial Therapies for the Clinic , 2012, Science Translational Medicine.

[11]  I. Kochevar,et al.  Light‐activated tissue bonding for excisional wound closure: a split‐lesion clinical trial , 2012, The British journal of dermatology.

[12]  Denise Rizzolo,et al.  Laceration repair: avoid infection, optimize healing, minimize scarring. , 2011, JAAPA : official journal of the American Academy of Physician Assistants.

[13]  J. Scaiano,et al.  Photophysics and photochemistry of dyes bound to human serum albumin are determined by the dye localization , 2010, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

[14]  R. Forsch.  Essentials of skin laceration repair. , 2008, American family physician.

[15]  D. Mawad,et al.  Adhesive biomaterials for tissue reconstruction , 2008 .

[16]  Hirotaka Akita,et al.  Evaluation of photochemical tissue bonding for closure of skin incisions and excisions , 2005, Lasers in surgery and medicine.

[17]  J. Sichel,et al.  Adverse reaction to surgical sutures in thyroid surgery , 2003, Head & neck.

[18]  M Kon,et al.  The Role of Suture Material in Hypertrophic Scar Formation: Monocryl vs. Vicryl-rapide , 1997, Annals of plastic surgery.

[19]  D Mackenzie,et al.  The history of sutures. , 1973, Medical History.