CONTENT OF NUTRITIONAL HONEY Moringa Oleifera NUTRITION AND GLYCEMIC INDEX VALUE ON PREGNANCY RATS (RATTUS NORVEGICUS)

Honey has been widely used as a substitute for sugar, especially during pregnancy that requires food intake with a low glycemic index (GI). The aim of this study to assess the nutritional content and IG of honey Moringa in pregnant wistar rats. The research method is experimental research lab to design Randomized Post Test Only Control Group Design on GI and Proximate analysis and phytochemical analysis of the nutrient content of Moringa honey. The research sample used 24 pregnancy rats into 1 control group (0.22ml) and 3 honey intervention group (0.27ml) consisting 6 animals each. Intervention in 14 days with measurement GI on gestation day 14. Analysis use correlation method AUC to show value of GI and statistical analysis using the One-Way ANOVA, followed by post hoc test analysis test methods LSD. The results study of carbohydrate content honey plus Moringa do not reach SNI, protein and fat reach SNI, for carbohydrate, protein and fat content of Moringa honey reach SNI, while the flavonoid content be higher in honey and polyphenol content is higher in Moringa honey. The results animal studies of GI honey (61), honey plus moringa (62.07) and honey moringa (65.05) are medium category (55-70). The results significant differences in food group reference to the intervention group. The results of post hoc LSD was no significant difference between the natural honey (105.17), Honey plus moringa (126.50) and honey moringa (132.83) in comparison Glycemic value. Honey, honey plus moringa and honey moringa can control the GI in pregnancy

[1]  P. Neumann,et al.  A Look into the Cell: Honey Storage in Honey Bees, Apis mellifera , 2016, PloS one.

[2]  Parada Javier,et al.  Phenolic content of honey reduces in vitro starch digestibility , 2016 .

[3]  Rosdiana Natzir.  Pengaruh Antioksidan Madu Dorsata dan Madu Trigona terhadap Penghambatan Oksidasi LDL pada Mencit Hiperkolesterolemia , 2016 .

[4]  Hai-rim Shin,et al.  WHO Western Pacific Regional Action Plan for the Prevention and Control of NCDs (2014-2020) , 2014, Epidemiology and health.

[5]  M. Hawlader,et al.  Identification of Phenolic Acids and Flavonoids in Monofloral Honey from Bangladesh by High Performance Liquid Chromatography: Determination of Antioxidant Capacity , 2014, BioMed research international.

[6]  M. C. Seijo,et al.  Near infrared spectroscopy for prediction of antioxidant compounds in the honey. , 2013, Food chemistry.

[7]  L. Estevinho,et al.  Comparative study of the physicochemical and palynological characteristics of honey from Melipona subnitida and Apis mellifera , 2013 .

[8]  P. Sil,et al.  D-saccharic acid 1,4-lactone protects diabetic rat kidney by ameliorating hyperglycemia-mediated oxidative stress and renal inflammatory cytokines via NF-κB and PKC signaling. , 2013, Toxicology and applied pharmacology.

[9]  S. A. Sulaiman,et al.  Fructose Might Contribute to the Hypoglycemic Effect of Honey , 2012, Molecules.

[10]  P. Soewondo,et al.  Prevalence, characteristics, and predictors of pre-diabetes in Indonesia , 2011 .

[11]  Paola Astolfi,et al.  Antioxidant and antimicrobial capacity of several monofloral Cuban honeys and their correlation with color, polyphenol content and other chemical compounds. , 2010, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

[12]  S. A. Sulaiman,et al.  Studies on the antioxidant properties of Tualang honey of Malaysia. , 2010, African journal of traditional, complementary, and alternative medicines : AJTCAM.

[13]  A. M. Thannoun.  BLOOD GLUCOSE RESPONSE AND GLYCEMIC INDEX OF DIETS CONTAINING DIFFERENT SOURCES OF CARBOHYDRATE IN HEALTHY RATS , 2010 .

[14]  S. Sreelatha,et al.  Antioxidant Activity and Total Phenolic Content of Moringa oleifera Leaves in Two Stages of Maturity , 2009, Plant foods for human nutrition.

[15]  L. Estevinho,et al.  Antioxidant activity of Portuguese honey samples: Different contributions of the entire honey and phenolic extract , 2009 .

[16]  R. Moses,et al.  Can a Low–Glycemic Index Diet Reduce the Need for Insulin in Gestational Diabetes Mellitus? , 2009, Diabetes Care.

[17]  D. van der A,et al.  Glycemic index and glycemic load in relation to food and nutrient intake and metabolic risk factors in a Dutch population. , 2008, The American journal of clinical nutrition.

[18]  M. Quon,et al.  EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHR. , 2007, American journal of physiology. Endocrinology and metabolism.

[19]  J. Dunn,et al.  Perspectives in Gestational Diabetes Mellitus: A Review of Screening, Diagnosis, and Treatment , 2007 .

[20]  F Xavier Pi-Sunyer,et al.  Dietary carbohydrate (amount and type) in the prevention and management of diabetes: a statement by the american diabetes association. , 2004, Diabetes care.

[21]  I. O. Steve,et al.  Determination of nutrient compositions , glyceamic index and ant-diabetic potentials of multi-plant based functional foods in rats , 2016 .

[22]  I. Ezekiel.  Effect of Ethanolic Leaves Extract of Moringa oleifera on Blood Glucose Levels of Streptozocin-Induced Diabetics and Normoglycemic Wistar Rats , 2011 .

[23]  Mojca Jamnik,et al.  Analytical, Nutritional and Clinical Methods Evaluation of the phenolic content, antioxidant activity and colour of Slovenian honey , 2007 .