Activation of hepatocyte growth factor-met autocrine loop enhances tumorigenicity in a human lung adenocarcinoma cell line.

[1]  E. Lengyel,et al.  Activation Mechanisms of the Urokinase-type Plasminogen Activator Promoter by Hepatocyte Growth Factor/Scatter Factor* , 1999, The Journal of Biological Chemistry.

[2]  T. Nakamura,et al.  Hepatocyte growth factor increases expression of vascular endothelial growth factor and plasminogen activator inhibitor-1 in human keratinocytes and the vascular endothelial growth factor receptor flk-1 in human endothelial cells. , 1999, Laboratory investigation; a journal of technical methods and pathology.

[3]  R. Kaufmann,et al.  Hepatocyte growth factor/scatter factor (HGF/SF) induces vascular permeability factor (VPF/VEGF) expression by cultured keratinocytes. , 1998, The Journal of investigative dermatology.

[4]  C. Birchmeier,et al.  Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. , 1998, Trends in cell biology.

[5]  K. Sekiguchi,et al.  Decreased fibronectin expression in Met/HGF-mediated tumorigenesis , 1998, Oncogene.

[6]  M. Tsao,et al.  The roles of hepatocyte growth factor/scatter factor and met receptor in human cancers (Review). , 1998, Oncology reports.

[7]  L. Trusolino,et al.  Growth Factor–dependent Activation of αvβ3 Integrin in Normal Epithelial Cells: Implications for Tumor Invasion , 1998, The Journal of cell biology.

[8]  H. Kataoka,et al.  Up-regulation of vascular endothelial growth factor induced by hepatocyte growth factor/scatter factor stimulation in human glioma cells. , 1998, Biochemical and biophysical research communications.

[9]  T. Nakamura,et al.  Paracrine effects of hepatocyte growth factor/scatter factor on non-small-cell lung carcinoma cell lines. , 1998, British Journal of Cancer.

[10]  M. Tsao,et al.  Differential expression of Met/hepatocyte growth factor receptor in subtypes of non-small cell lung cancers. , 1998, Lung cancer.

[11]  B. Davidson,et al.  Adenovirus-mediated manganese superoxide dismutase gene transfer to hamster cheek pouch carcinoma cells. , 1997, Cancer research.

[12]  M. Tsao,et al.  Angiogenesis correlates with vascular endothelial growth factor expression but not with Ki-ras oncogene activation in non-small cell lung carcinoma. , 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

[13]  E. Rosen,et al.  Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo. , 1997, Laboratory investigation; a journal of technical methods and pathology.

[14]  L. Jin,et al.  Scatter factor stimulates tumor growth and tumor angiogenesis in human breast cancers in the mammary fat pads of nude mice. , 1997, Laboratory investigation; a journal of technical methods and pathology.

[15]  L. Weissfeld,et al.  Association of immunoreactive hepatocyte growth factor with poor survival in resectable non-small cell lung cancer. , 1997, Cancer research.

[16]  R. Sharp,et al.  Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[17]  R. Ball,et al.  IMMUNOREACTIVITY FOR HEPATOCYTE GROWTH FACTOR/SCATTER FACTOR AND ITS RECEPTOR, met, IN HUMAN LUNG CARCINOMAS AND MALIGNANT MESOTHELIOMAS , 1996, The Journal of pathology.

[18]  P. Comoglio,et al.  Overexpression and activation of hepatocyte growth factor/scatter factor in human non-small-cell lung carcinomas. , 1996, British Journal of Cancer.

[19]  T. Yamamoto,et al.  Hepatocyte growth factor and c-Met/hepatocyte growth factor receptor in pulmonary adenocarcinomas: an evaluation of their expression as prognostic markers. , 1996, Oncology.

[20]  K. Matsumoto,et al.  Emerging multipotent aspects of hepatocyte growth factor. , 1996, Journal of biochemistry.

[21]  G. V. Vande Woude,et al.  Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis network , 1996, Molecular and cellular biology.

[22]  J. Minna,et al.  NCI‐navy medical oncology branch cell line data base , 1996, Journal of cellular biochemistry. Supplement.

[23]  T. Nakamura,et al.  Hepatocyte growth factor in lung morphogenesis and tumor invasion: role as a mediator in epithelium-mesenchyme and tumor-stroma interactions , 1996, Cancer Chemotherapy and Pharmacology.

[24]  W. Birchmeier,et al.  Hepatocyte growth factor/scatter factor induces a variety of tissue- specific morphogenic programs in epithelial cells , 1995, The Journal of cell biology.

[25]  R. Schwall,et al.  Sulfated Oligosaccharides Promote Hepatocyte Growth Factor Association and Govern Its Mitogenic Activity (*) , 1995, The Journal of Biological Chemistry.

[26]  E. Rosen,et al.  Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction , 1994, The Journal of cell biology.

[27]  G. V. Vande Woude,et al.  Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[28]  T. Nakamura,et al.  Creation of an hepatocyte growth factor/scatter factor autocrine loop in carcinoma cells induces invasive properties associated with increased tumorigenicity. , 1994, Oncogene.

[29]  T. Nakamura,et al.  Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[30]  H. Kleinman,et al.  Scatter factor induces blood vessel formation in vivo. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[31]  T. Nakamura,et al.  Expression of the proto-oncogenes c-met and c-kit and their ligands, hepatocyte growth factor/scatter factor and stem cell factor, in SCLC cell lines and xenografts. , 1993, British Journal of Cancer.

[32]  W. Birchmeier,et al.  Extracellular proteolytic cleavage by urokinase is required for activation of hepatocyte growth factor/scatter factor. , 1992, The EMBO journal.

[33]  L. Naldini,et al.  Hepatocyte growth factor is a potent angiogenic factor which stimulates endothelial cell motility and growth , 1992, The Journal of cell biology.

[34]  D. Littman,et al.  Packaging system for rapid production of murine leukemia virus vectors with variable tropism , 1992, Journal of virology.

[35]  L. Orci,et al.  Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor , 1991, Cell.

[36]  W. Birchmeier,et al.  Evidence for the identity of human scatter factor and human hepatocyte growth factor. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[37]  M. Naujokas,et al.  Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing , 1991, Molecular and cellular biology.

[38]  J. Rubin,et al.  Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. , 1991, Science.

[39]  W. Birchmeier,et al.  Evidence for the identy of human scatter factor and human hepatocyte growth factor. , 1991 .

[40]  J Vandekerckhove,et al.  Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cells , 1990, The Journal of cell biology.

[41]  D. Goeddel,et al.  Vascular endothelial growth factor is a secreted angiogenic mitogen. , 1989, Science.

[42]  K. Tashiro,et al.  Molecular cloning and expression of human hepatocyte growth factor , 1989, Nature.

[43]  Miller Ad,et al.  Improved Retroviral Vectors for Gene Transfer and Expression , 1989 .

[44]  E. Gherardi,et al.  Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[45]  M. Tsao,et al.  Gradation of carcinogen-induced capacity for anchorage-independent growth in cultured rat liver epithelial cells. , 1985, Cancer research.