The rs483145 polymorphism of MC4R gene is not associated with obesity in the Chilean population: Results of GENADIO study.

[1]  M. Martorell,et al.  Genetic variants in the SLC16A11 gene are associated with increased BMI and insulin levels in nondiabetic Chilean population , 2021, Archives of endocrinology and metabolism.

[2]  A. Markham.  Setmelanotide: First Approval , 2021, Drugs.

[3]  W. Chung,et al.  Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials. , 2020, The lancet. Diabetes & endocrinology.

[4]  C. Celis-Morales,et al.  [The interaction of our genes with the obesogenic environment]. , 2019, Revista medica de Chile.

[5]  F. Petermann-Rocha,et al.  Asociación del polimorfismo rs7903146, del gen TCF7L2, con marcadores de adiposidad y metabólicos en población chilena - resultados del estudio GENADIO , 2019, Revista médica de Chile.

[6]  J. Bjørngaard,et al.  Quantifying the impact of genes on body mass index during the obesity epidemic: longitudinal findings from the HUNT Study , 2019, BMJ.

[7]  B. Shah,et al.  Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation , 2019, Molecules.

[8]  Marti,et al.  Melanocortin-4 Receptor and Lipocalin 2 Gene Variants in Spanish Children with Abdominal Obesity: Effects on BMI-SDS after a Lifestyle Intervention , 2019, Nutrients.

[9]  Chen Li,et al.  Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity , 2019, Cell.

[10]  Y. Böttcher,et al.  Genetics and epigenetics in obesity. , 2019, Metabolism: clinical and experimental.

[11]  H. Biebermann,et al.  Melanocortin-4 Receptor Signalling: Importance for Weight Regulation and Obesity Treatment. , 2019, Trends in molecular medicine.

[12]  Yuki Kimura,et al.  Genetic variations in the monocarboxylate transporter genes (SLC16A1, SLC16A3, and SLC16A11) in the Japanese population. , 2018, Drug metabolism and pharmacokinetics.

[13]  Tie-Lin Yang,et al.  Comprehensive review and annotation of susceptibility SNPs associated with obesity‐related traits , 2018, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[14]  C. Troncoso,et al.  Asociación entre el polimorfismo rs9939609 del gen FTO y marcadores de adiposidad en población adulta chilena , 2018, Revista médica de Chile.

[15]  Marcelo P. Segura-Lepe,et al.  Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure underpinning obesity , 2017, Nature Genetics.

[16]  Paul C. Fletcher,et al.  Divergent effects of central melanocortin signalling on fat and sucrose preference in humans , 2016, Nature Communications.

[17]  Tran Quoc Bao,et al.  Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants , 2016, The Lancet.

[18]  J. Santos,et al.  Melanocortin-4 Receptor Gene Variation Is Associated with Eating Behavior in Chilean Adults , 2015, Annals of Nutrition and Metabolism.

[19]  C. Bogardus,et al.  Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children , 2014, Human Genetics.

[20]  I. Guzmán-Guzmán,et al.  Melanocortin-4 receptor polymorphism rs17782313: association with obesity and eating in the absence of hunger in Chilean children. , 2014, Nutrition.

[21]  G. Chandak,et al.  Association between Common Polymorphism near the MC4R Gene and Obesity Risk: A Systematic Review and Meta-Analysis , 2012, PloS one.

[22]  T. Reilly,et al.  Prediction of segmental lean mass using anthropometric variables in young adults , 2012, Jurnal sport science.

[23]  C. Celis-Morales,et al.  Insulin Resistance in Chileans of European and Indigenous Descent: Evidence for an Ethnicity x Environment Interaction , 2011, PloS one.

[24]  R. Loos,et al.  The genetic epidemiology of melanocortin 4 receptor variants. , 2011, European journal of pharmacology.

[25]  Y. Tao.  The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology. , 2010, Endocrine reviews.

[26]  J. Santos,et al.  Melanocortin-4 receptor gene variants in Chilean families: association with childhood obesity and eating behavior , 2010, Nutritional neuroscience.

[27]  T. Hansen,et al.  Variants Near MC4R Are Associated With Obesity and Influence Obesity-Related Quantitative Traits in a Population of Middle-Aged People: Studies of 14,940 Danes , 2009, Diabetes.

[28]  Subhajyoti De,et al.  Common variants near MC4R are associated with fat mass, weight and risk of obesity , 2008, Nature Genetics.

[29]  O. Ilnytska,et al.  The Role of the Agouti-Related Protein in Energy Balance Regulation , 2008, Cellular and Molecular Life Sciences.

[30]  I. Gantz,et al.  The melanocortin system. , 2003, American journal of physiology. Endocrinology and metabolism.

[31]  S. O’Rahilly,et al.  Dominant and recessive inheritance of morbid obesity associated with melanocortin 4 receptor deficiency. , 2000, The Journal of clinical investigation.

[32]  P S Freedson,et al.  Calibration of the Computer Science and Applications, Inc. accelerometer. , 1998, Medicine and science in sports and exercise.

[33]  R. Cone,et al.  Targeted Disruption of the Melanocortin-4 Receptor Results in Obesity in Mice , 1997, Cell.

[34]  P. R. Jones,et al.  [Validity of skinfold thickness as an estimation of fatty mass, with reference to the equations of Durnin and Womersley (author's transl)]. , 1980, Revista medica de Chile.