Pioneer work by Professor Dudgeon in cytological diagnosis
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Almost 40 years ago, shortly after the end of the First World War, Professor L. S. Dudgeon, Professor of Pathology at St. Thomas's Hospital, London, began to take an ever-increasing interest in cytology. The reason why he did so is not clear but it may possibly be explained in part by his association with the late Dr. C. M. Wenyon, the distinguished protozoologist, during their service with the R.A.M.C. in Macedonia. Dudgeon began to use the cytological method for the examination of fresh tissues from various parts of the body. The technique he employed, the 'wet-film' technique, was very simple. The tissue removed fresh from operation is incised and scraped with a sharp scalpel. The juice thus
[1] C. Wrigley,et al. On the Demonstration of Particles of Malignant Growth in the Sputum by Means of the Wet-Film Method , 1935, The Journal of Laryngology & Otology.
[2] A. Wrigley. A Method of Rapid Diagnosis of Pathological Specimens. , 1932 .