Xenon for NMR biosensing--inert but alert.

[1]  K. Holman.  Cryptophanes: Molecular Containers , 2013 .

[2]  V. Bajaj,et al.  Band-selective chemical exchange saturation transfer imaging with hyperpolarized xenon-based molecular sensors. , 2011, Journal of magnetic resonance.

[3]  M. Carrière,et al.  Hyperpolarized 129Xe NMR signature of living biological cells , 2011, NMR in biomedicine.

[4]  J. Dutasta,et al.  Cell uptake of a biosensor detected by hyperpolarized 129Xe NMR: the transferrin case. , 2011, Bioorganic & medicinal chemistry.

[5]  L. Laureano-Pérez,et al.  Measurement of radon and xenon binding to a cryptophane molecular host , 2011, Proceedings of the National Academy of Sciences.

[6]  I. Dmochowski,et al.  Cell-compatible, integrin-targeted cryptophane-129Xe NMR biosensors. , 2011, Chemical science.

[7]  P. Berthault,et al.  Interaction of xenon with cucurbit[5]uril in water. , 2011, Chemphyschem : a European journal of chemical physics and physical chemistry.

[8]  J. Dognon,et al.  Design and synthesis of new cryptophanes with intermediate cavity sizes. , 2011, Organic letters.

[9]  M. Barlow,et al.  Interdependence of in-cell xenon density and temperature during Rb/129Xe spin-exchange optical pumping using VHG-narrowed laser diode arrays. , 2011, Journal of magnetic resonance.

[10]  I. Dmochowski,et al.  Crystallographic observation of 'induced fit' in a cryptophane host–guest model system , 2010, Nature communications.

[11]  A. Pines,et al.  MRI thermometry based on encapsulated hyperpolarized xenon. , 2010, Chemphyschem : a European journal of chemical physics and physical chemistry.

[12]  J. Dutasta,et al.  Effect of pH and counterions on the encapsulation properties of xenon in water-soluble cryptophanes. , 2010, Chemistry.

[13]  J. Dutasta,et al.  A water-soluble Xe@cryptophane-111 complex exhibits very high thermodynamic stability and a peculiar (129)Xe NMR chemical shift. , 2010, Journal of the American Chemical Society.

[14]  R. Lenkinski,et al.  CEST and PARACEST MR contrast agents , 2010, Acta radiologica.

[15]  A. Pines,et al.  Xenon-based molecular sensors in lipid suspensions. , 2010, Journal of magnetic resonance.

[16]  V. Bajaj,et al.  A xenon-based molecular sensor assembled on an MS2 viral capsid scaffold. , 2010, Journal of the American Chemical Society.

[17]  P. V. van Zijl,et al.  Indirect detection of labile solute proton spectra via the water signal using frequency-labeled exchange (FLEX) transfer. , 2010, Journal of the American Chemical Society.

[18]  R. Gobetto,et al.  Hyperpolarized agents for advanced MRI investigations. , 2009, The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of....

[19]  J. Dutasta,et al.  Encapsulation of small gas molecules by cryptophane-111 in organic solution. 1. Size- and shape-selective complexation of simple hydrocarbons. , 2009, The journal of physical chemistry. A.

[20]  H. Spiess,et al.  Magnetic resonance imaging of dissolved hyperpolarized 129Xe using a membrane-based continuous flow system. , 2009, Journal of magnetic resonance.

[21]  A. Pines,et al.  Hyperpolarized xenon NMR and MRI signal amplification by gas extraction , 2009, Proceedings of the National Academy of Sciences.

[22]  Sonny C. Hsiao,et al.  Viral capsid DNA aptamer conjugates as multivalent cell-targeting vehicles. , 2009, Journal of the American Chemical Society.

[23]  R. Gillies,et al.  Responsive MRI agents for sensing metabolism in vivo. , 2009, Accounts of chemical research.

[24]  H. Desvaux,et al.  Biosensing using laser-polarized xenon NMR/MRI , 2009 .

[25]  Enzo Terreno,et al.  Pushing the sensitivity envelope of lanthanide-based magnetic resonance imaging (MRI) contrast agents for molecular imaging applications. , 2009, Accounts of chemical research.

[26]  L. Mitschang,et al.  A xenon-129 biosensor for monitoring MHC-peptide interactions. , 2009, Angewandte Chemie.

[27]  M. Barlow,et al.  Generation of laser-polarized xenon using fiber-coupled laser-diode arrays narrowed with integrated volume holographic gratings. , 2009, Journal of magnetic resonance.

[28]  K. D. Atkinson,et al.  Reversible Interactions with para-Hydrogen Enhance NMR Sensitivity by Polarization Transfer , 2009, Science.

[29]  T. Troxler,et al.  Substituent effects on xenon binding affinity and solution behavior of water-soluble cryptophanes. , 2009, Journal of the American Chemical Society.

[30]  D. Christianson,et al.  Cryptophane xenon-129 nuclear magnetic resonance biosensors targeting human carbonic anhydrase. , 2009, Journal of the American Chemical Society.

[31]  I. Dmochowski,et al.  Peptide-mediated cellular uptake of cryptophane. , 2008, Bioconjugate chemistry.

[32]  H. Desvaux,et al.  Sensitivity and multiplexing capabilities of MRI based on polarized 129Xe biosensors. , 2008, Journal of the American Chemical Society.

[33]  J. Dutasta,et al.  Cryptophane-xenon complexes in organic solvents observed through NMR spectroscopy. , 2008, The journal of physical chemistry. A.

[34]  A Dean Sherry,et al.  Chemical exchange saturation transfer contrast agents for magnetic resonance imaging. , 2008, Annual review of biomedical engineering.

[35]  Shoujun Xu,et al.  Novel detection schemes of nuclear magnetic resonance and magnetic resonance imaging: applications from analytical chemistry to molecular sensors. , 2008, Annual review of analytical chemistry.

[36]  Y. Ko,et al.  Water soluble cucurbit[6]uril derivative as a potential Xe carrier for 129Xe NMR-based biosensors. , 2008, Chemical communications.

[37]  D. Christianson,et al.  Structure of a 129Xe-cryptophane biosensor complexed with human carbonic anhydrase II. , 2008, Journal of the American Chemical Society.

[38]  A. Pines,et al.  Temperature-controlled molecular depolarization gates in nuclear magnetic resonance. , 2008, Angewandte Chemie.

[39]  Leif Schröder,et al.  Temperature response of 129Xe depolarization transfer and its application for ultrasensitive NMR detection. , 2008, Physical review letters.

[40]  M. Botta,et al.  High relaxivity gadolinium hydroxypyridonate-viral capsid conjugates: nanosized MRI contrast agents. , 2008, Journal of the American Chemical Society.

[41]  T. Delair,et al.  A cryptophane biosensor for the detection of specific nucleotide targets through xenon NMR spectroscopy. , 2007, Chemphyschem : a European journal of chemical physics and physical chemistry.

[42]  E. Brunner,et al.  Optimization of continuous flow pump cells used for the production of hyperpolarized 129Xe: A theoretical study , 2007 .

[43]  J. Dutasta,et al.  A cryptophane core optimized for xenon encapsulation. , 2007, Journal of the American Chemical Society.

[44]  J. Feeney,et al.  Forty years of Progress in Nuclear Magnetic Resonance Spectroscopy , 2007 .

[45]  M. Botta,et al.  Magnetic resonance contrast agents from viral capsid shells: a comparison of exterior and interior cargo strategies. , 2007, Nano letters.

[46]  R. Eckenhoff,et al.  Thermodynamics of xenon binding to cryptophane in water and human plasma. , 2007, Journal of the American Chemical Society.

[47]  Ralph Weissleder,et al.  Emerging concepts in molecular MRI. , 2007, Current opinion in biotechnology.

[48]  Katherine A. Koen,et al.  Time-of-flight flow imaging of two-component flow inside a microfluidic chip. , 2007, Physical review letters.

[49]  Bastiaan Driehuys,et al.  Imaging Techniques for Small Animal Models of Pulmonary Disease: MR Microscopy , 2007, Toxicologic pathology.

[50]  A. Pines,et al.  Diastereomeric Xe chemical shifts in tethered cryptophane cages. , 2006, Journal of the American Chemical Society.

[51]  Christian Hilty,et al.  Molecular Imaging Using a Targeted Magnetic Resonance Hyperpolarized Biosensor , 2006, Science.

[52]  I. Dmochowski,et al.  Designing 129Xe NMR biosensors for matrix metalloproteinase detection. , 2006, Journal of the American Chemical Society.

[53]  B. Franc,et al.  Intracellular cargo delivery by an octaarginine transporter adapted to target prostate cancer cells through cell surface protease activation. , 2006, Bioconjugate chemistry.

[54]  A. Pines,et al.  Xenon biosensor amplification via dendrimer-cage supramolecular constructs. , 2006, Journal of the American Chemical Society.

[55]  L. Dubois,et al.  Water soluble cryptophanes showing unprecedented affinity for xenon: candidates as NMR-based biosensors. , 2006, Journal of the American Chemical Society.

[56]  Sharon Bloch,et al.  Design, synthesis, and evaluation of near infrared fluorescent multimeric RGD peptides for targeting tumors. , 2006, Journal of medicinal chemistry.

[57]  Jinyuan Zhou,et al.  Quantifying exchange rates in chemical exchange saturation transfer agents using the saturation time and saturation power dependencies of the magnetization transfer effect on the magnetic resonance imaging signal (QUEST and QUESP): Ph calibration for poly‐L‐lysine and a starburst dendrimer , 2006, Magnetic resonance in medicine.

[58]  I. Ruset,et al.  Optical pumping system design for large production of hyperpolarized. , 2006, Physical review letters.

[59]  Enzo Terreno,et al.  Highly sensitive MRI chemical exchange saturation transfer agents using liposomes. , 2005, Angewandte Chemie.

[60]  A. Pines,et al.  Optimization of Xenon Biosensors for Detection of Protein Interactions , 2005, Chembiochem : a European journal of chemical biology.

[61]  Jinyuan Zhou,et al.  Optimization of the irradiation power in chemical exchange dependent saturation transfer experiments. , 2005, Journal of magnetic resonance.

[62]  A. Pines,et al.  Spectrally resolved magnetic resonance imaging of a xenon biosensor. , 2005, Angewandte Chemie.

[63]  A. Pines,et al.  NMR-based biosensing with optimized delivery of polarized 129Xe to solutions. , 2005, Analytical chemistry.

[64]  Enzo Terreno,et al.  Tunable imaging of cells labeled with MRI-PARACEST agents. , 2005, Angewandte Chemie.

[65]  Vladimir P Torchilin,et al.  Intracellular delivery of large molecules and small particles by cell-penetrating proteins and peptides. , 2005, Advanced drug delivery reviews.

[66]  N. Shah,et al.  Hyperpolarized xenon in NMR and MRI. , 2004, Physics in medicine and biology.

[67]  E. D. Melnik,et al.  Wavelength stabilization and spectrum narrowing of high-power multimode laser diodes and arrays by use of volume Bragg gratings. , 2004, Optics letters.

[68]  Philip A. Gale,et al.  Encyclopedia of Supramolecular Chemistry , 2004 .

[69]  W. Kilian,et al.  Dynamic NMR spectroscopy of hyperpolarized 129Xe in human brain analyzed by an uptake model , 2004, Magnetic resonance in medicine.

[70]  P. Schultz,et al.  Development of a functionalized xenon biosensor. , 2004, Journal of the American Chemical Society.

[71]  R. Khokha,et al.  Molecular mechanisms of tumor invasion and metastasis: an integrated view. , 2003, Current molecular medicine.

[72]  J. Ardenkjær-Larsen,et al.  Increase in signal-to-noise ratio of > 10,000 times in liquid-state NMR , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[73]  Robert E Lenkinski,et al.  PARACEST agents: modulating MRI contrast via water proton exchange. , 2003, Accounts of chemical research.

[74]  A. Cherubini,et al.  Hyperpolarised xenon in biology , 2003 .

[75]  Peter C M van Zijl,et al.  Sensitive CEST agents based on nucleic acid imino proton exchange: Detection of poly(rU) and of a dendrimer‐poly(rU) model for nucleic acid delivery and pharmacology , 2003, Magnetic resonance in medicine.

[76]  Sunil Saxena,et al.  Amplification of xenon NMR and MRI by remote detection , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[77]  S. Gambhir,et al.  Molecular imaging in living subjects: seeing fundamental biological processes in a new light. , 2003, Genes & development.

[78]  J. Dutasta,et al.  Xe@cryptophane Complexes with C2 Symmetry: Synthesis and Investigations by 129Xe NMR of the Consequences of the Size of the Host Cavity for Xenon Encapsulation , 2003 .

[79]  Bhavin B. Adhyaru,et al.  High capacity production of >65% spin polarized xenon-129 for NMR spectroscopy and imaging. , 2002, Journal of magnetic resonance.

[80]  E. Hughes,et al.  Tunable diode laser study of pressure broadening of Rb D1 lines in the presence of 4He buffer gas , 2002 .

[81]  Eduard E de Lange,et al.  MRI of the lungs using hyperpolarized noble gases , 2002, Magnetic resonance in medicine.

[82]  B. M. Goodson,et al.  Nuclear magnetic resonance of laser-polarized noble gases in molecules, materials, and organisms. , 2002, Journal of magnetic resonance.

[83]  A. Pines,et al.  Functionalized xenon as a biosensor , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[84]  J. Bulte,et al.  Sensitive NMR detection of cationic-polymer-based gene delivery systems using saturation transfer via proton exchange. , 2001, Journal of the American Chemical Society.

[85]  W Happer,et al.  Energy transport in high-density spin-exchange optical pumping cells. , 2001, Physical review letters.

[86]  A. Sherry,et al.  A novel europium(III)-based MRI contrast agent. , 2001, Journal of the American Chemical Society.

[87]  J P Mugler,et al.  Probing lung physiology with xenon polarization transfer contrast (XTC) , 2000, Magnetic resonance in medicine.

[88]  Ralph Weissleder,et al.  Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells , 2000, Nature Biotechnology.

[89]  R S Balaban,et al.  A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST). , 2000, Journal of magnetic resonance.

[90]  J. Dutasta,et al.  129Xe and 1H NMR Study of the Reversible Trapping of Xenon by Cryptophane-A in Organic Solution , 1998 .

[91]  T. Walker,et al.  Spin-exchange optical pumping of noble-gas nuclei , 1997 .

[92]  R. Bryant,et al.  Nuclear magnetic cross-relaxation spectroscopy , 1990 .

[93]  Bowers,et al.  Transformation of symmetrization order to nuclear-spin magnetization by chemical reaction and nuclear magnetic resonance. , 1986, Physical review letters.

[94]  A. Collet,et al.  SYNTHESIS OF (D3)-BIS(CYCLOTRIVERATRYLENYL) MACROCAGE BY STEREOSPECIFIC REPLICATION OF A (C3)-SUBUNIT , 1982 .

[95]  A. Constantinesco,et al.  Towards thrombosis-targeted zeolite nanoparticles for laser-polarized 129Xe MRI , 2009 .

[96]  J. Dutasta,et al.  Cryptophanes and their complexes--present and future. , 2009, Chemical reviews.

[97]  Silvio Aime,et al.  Agents for polarization enhancement in MRI. , 2008, Handbook of experimental pharmacology.

[98]  A. Pines,et al.  Sensitivity enhancement by exchange mediated magnetization transfer of the xenon biosensor signal. , 2007, Journal of magnetic resonance.

[99]  Jimmy D. Bell,et al.  Modern Magnetic Resonance , 2006 .

[100]  A. S. Kertes,et al.  SOLUBILITY DATA SERIES , 1985 .

[101]  A. Collet,et al.  Synthesis of a (D3)-bis(cyclotriveratrylenyl) macrocage by stereospecific replication of a (C3)-subunit , 1981 .