Autophagy, cell death and sustained senescence arrest in B16/F10 melanoma cells and HCT-116 colon carcinoma cells in response to the novel microtubule poison, JG-03-14

[1]  K. Valerie,et al.  The Autophagy-Senescence Connection in Chemotherapy: Must Tumor Cells (Self) Eat Before They Sleep? , 2012, Journal of Pharmacology and Experimental Therapeutics.

[2]  D. Nolan,et al.  The vascular targeting agent Combretastatin-A4 directly induces autophagy in adenocarcinoma-derived colon cancer cells. , 2012, Biochemical pharmacology.

[3]  A. Ocean,et al.  Peripheral neuropathy with microtubule-targeting agents: occurrence and management approach. , 2011, Clinical breast cancer.

[4]  M. Hayley,et al.  微小管安定化剤と老化誘導剤,ディスコデルモリドに対する耐性は4E-BP1に依存する , 2011 .

[5]  J. Brouwer-Visser,et al.  Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1–dependent , 2010, Proceedings of the National Academy of Sciences.

[6]  I. Petersen,et al.  Cellular senescence predicts treatment outcome in metastasised colorectal cancer , 2010, British Journal of Cancer.

[7]  D. Gewirtz,et al.  Interference with endothelial cell function by JG-03-14, an agent that binds to the colchicine site on microtubules. , 2009, Biochemical pharmacology.

[8]  Thomas Tüting,et al.  Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells. , 2009, Cancer cell.

[9]  S. Fulda Tumor resistance to apoptosis , 2009, International journal of cancer.

[10]  H. Vihinen,et al.  Monitoring autophagy by electron microscopy in Mammalian cells. , 2009, Methods in enzymology.

[11]  G. Bjørkøy,et al.  Monitoring autophagic degradation of p62/SQSTM1. , 2009, Methods in enzymology.

[12]  P. Codogno,et al.  Does autophagy have a license to kill mammalian cells? , 2009, Cell Death and Differentiation.

[13]  L. Elmore,et al.  Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation. , 2008, Biochemical pharmacology.

[14]  A. Calcabrini,et al.  The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells , 2008, Autophagy.

[15]  B. Zhivotovsky,et al.  Death through a tragedy: mitotic catastrophe , 2008, Cell Death and Differentiation.

[16]  R. Schwartz Management of early and advanced colorectal cancer: therapeutic issues. , 2008, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[17]  J. Arezzo,et al.  Neuropathy associated with microtubule inhibitors: diagnosis, incidence, and management. , 2008, Clinical advances in hematology & oncology : H&O.

[18]  J. Glass,et al.  Interleukin-6 protects against paclitaxel, cisplatin and vincristine-induced neuropathies without impairing chemotherapeutic activity , 2008, Cancer Chemotherapy and Pharmacology.

[19]  H. Nielsen,et al.  Comparative studies of tissue inhibitor of metalloproteinases-1 in plasma, serum and tumour tissue extracts from patients with primary colorectal cancer , 2008, Scandinavian journal of gastroenterology.

[20]  M. Cabot,et al.  Autophagic cell death, polyploidy and senescence induced in breast tumor cells by the substituted pyrrole JG-03-14, a novel microtubule poison. , 2007, Biochemical pharmacology.

[21]  J. Campisi,et al.  Cellular senescence: when bad things happen to good cells , 2007, Nature Reviews Molecular Cell Biology.

[22]  Jonathan E. Hempel,et al.  Identification and Characterization of a New Tubulin-Binding Tetrasubstituted Brominated Pyrrole , 2007, Molecular Pharmacology.

[23]  A. Darzi,et al.  Apoptosis and chemo‐resistance in colorectal cancer , 2007, Journal of surgical oncology.

[24]  M. Niso-Santano,et al.  Inhibition of paraquat-induced autophagy accelerates the apoptotic cell death in neuroblastoma SH-SY5Y cells. , 2007, Toxicological sciences : an official journal of the Society of Toxicology.

[25]  R. Marais,et al.  Melanoma biology and new targeted therapy , 2007, Nature.

[26]  G. Evan,et al.  Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. , 2007, The Journal of clinical investigation.

[27]  I. Newsham,et al.  Potentiation of radiation sensitivity in breast tumor cells by the vitamin D3 analogue, EB 1089, through promotion of autophagy and interference with proliferative recovery , 2006, Molecular Cancer Therapeutics.

[28]  L. Chin,et al.  Malignant melanoma: genetics and therapeutics in the genomic era. , 2006, Genes & development.

[29]  R. Schmidt,et al.  Bafilomycin A1 Inhibits Chloroquine-Induced Death of Cerebellar Granule Neurons , 2006, Molecular Pharmacology.

[30]  L. Elmore,et al.  p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells , 2005, International journal of radiation biology.

[31]  E. Hwang,et al.  Dinstinct ROS and biochemical profiles in cells undergoing DNA damage-induced senescence and apoptosis , 2005, Mechanisms of Ageing and Development.

[32]  A. Tolkovsky,et al.  The Dynamics of Autophagy Visualised in Live Cells: from Autophagosome Formation to Fusion with Endo/lysosomes , 2005, Autophagy.

[33]  L. Elmore,et al.  Evasion of a Single-Step, Chemotherapy-Induced Senescence in Breast Cancer Cells: Implications for Treatment Response , 2005, Clinical Cancer Research.

[34]  Szu-Yu Chen,et al.  Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers. , 2005, Cancer research.

[35]  Ethaar El-Emir,et al.  Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice. , 2005, European journal of cancer.

[36]  Philippe Dessen,et al.  Inhibition of Macroautophagy Triggers Apoptosis , 2005, Molecular and Cellular Biology.

[37]  Adam P Dicker,et al.  Effect of the tumor vascular-damaging agent, ZD6126, on the radioresponse of U87 glioblastoma. , 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

[38]  Daniel J. Klionsky,et al.  Autophagy in Health and Disease: A Double-Edged Sword , 2004, Science.

[39]  S. Gultekin,et al.  Autophagy in human tumors: cell survival or death? , 2004, Cell Death and Differentiation.

[40]  S. Taillibert,et al.  Metastatic melanoma: chemotherapy. , 2002, Seminars in oncology.

[41]  T. Hollister,et al.  A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. , 2001, Cancer research.

[42]  Takeshi Noda,et al.  LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing , 2000, The EMBO journal.

[43]  D. Hanahan,et al.  The Hallmarks of Cancer , 2000, Cell.

[44]  D. Morgan,et al.  Characterization of Carbon Disulfide Neurotoxicity in C57BL6 Mice: Behavioral, Morphologic, and Molecular Effects , 2000, Toxicologic pathology.

[45]  E. Brambilla,et al.  In situ apoptotic cell labeling by the TUNEL method: improvement and evaluation on cell preparations. , 1996, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[46]  T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. , 1983, Journal of immunological methods.

[47]  P. Seglen,et al.  3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. , 1982, Proceedings of the National Academy of Sciences of the United States of America.