Case report: bone marrow visualization with Tc-99m disofenin

Technetium-99m-N-substituted iminodiacetic acid derivatives are currently being investigated in nuclear medicine for possible use in the evaluation of hepatobiliary diseases. Disofenin (diisopropyl iminodiacetic acid) is the derivative most highly regarded at present. A case is discussed in which, although Tc-99m disofenin was prepared according to the manufacturer's directions, an altered biodistribution pattern was noted on images.