Regional Distribution and Human Health Effects of Persistent Organic Pollutants (POPs) in Zhejiang Province

Zhejiang (ZJ) is a developed province located in the southeast coast of China. In recent years, growing concern has been aroused over the persistent organic pollutants (POPs) pollution associated with electronic and electric waste (e-waste) in this province. This chapter has provided numerous and integrated information concerning POPs pollution level and human health effects in ZJ. The residue levels of major POPs, including DDT, PCDD/Fs, PCBs and PCP/PCP-Na, in the environmental media, local food and human body were relatively higher in polluted areas of intensive e-waste dismantling industry compared with control areas. POPs pollution levels and cancer incidence in both polluted areas and control areas were comparable with the national data. In vitro test and population survey provided evidence that PCBs exposure altered the expression of genes involved in nervous systemand immune system-related diseases, and the CCL22 gene could serve as an effective biomarker for PCBs exposure. Additionally, e-waste management in ZJ province was discussed. Taken together, these data suggest that POPs pollution in ZJ may be correlated to local e-waste recycling activities. In the future, more efforts should be devoted to improve the techniques for e-waste recycling and establish a sound e-waste management framework.

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