论文信息 - Enzymatic Bromo-ether Cyclization of Laurediols with Bromoperoxidase

Enzymatic Bromo-ether Cyclization of Laurediols with Bromoperoxidase

Natural (3E,6R,7R)- and (3Z,6S,7S)-laurediols were subjected to enzymatic reaction with the partially purified bromoperoxidase from the red alga, Laurencia nipponica, in the presence of H2O2 and NaBr to afford laurencin and prelaureatin, respectively. The further reaction of these products with bromoperoxidase gave rise to the bicyclic bromo-ethers.

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