Efficacy of acitretin in the treatment of squamous cell carcinoma of the oral cavity.

A 50-year-old woman presented in April 2009 with ulcerative lesions of the oral cavity and a reddish nodular lesion, in correspondence to the left oropharyngeal tract, clinically suggestive of a malignant one (Fig. 1). She was referred with a 7-year history of leukoplakia and erosive oral lichen planus (OLP), and 2 years before she was treated with laser CO2 resection and radiotherapy for a squamous cell carcinoma of the palate with a good clinical response.

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