Strain imaging of internal deformation.

A tissue-like gelatin elasticity-flow phantom was examined to develop ultrasonic strain imaging for the detection of internal pulsatile deformations. The same imaging technique was then applied in vivo to monitor deformation in tissues surrounding the normal brachial artery. The results suggest that vascular strain patterns resulting from biologic stimuli are very different from those generated using externally applied stress fields, and are directly related to pressure variations within the vessel. These data suggest a potential role for strain imaging in measuring the relative pressure or vascular elasticity locally and noninvasively.

[1]  P. Chaturvedi,et al.  Testing the limitations of 2-D companding for strain imaging using phantoms , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[2]  J. Ophir,et al.  Elastography: Elasticity Imaging Using Ultrasound with Application to Muscle and Breast in Vivo , 1993, Ultrasonic imaging.

[3]  L. Katz,et al.  A Study of the Central and Peripheral Arterial Pressure Pulse in Man: Correlation with Simultaneously Recorded Electrokymograms , 1951, Circulation.

[4]  A F Mak,et al.  Estimating the effective Young's modulus of soft tissues from indentation tests--nonlinear finite element analysis of effects of friction and large deformation. , 1997, Medical engineering & physics.

[5]  Lysle H. Peterson,et al.  Mechanical Properties of Arteries in Vivo , 1960 .

[6]  I Céspedes,et al.  Noise reduction in elastograms using temporal stretching with multicompression averaging. , 1996, Ultrasound in medicine & biology.

[7]  E H WOOD,et al.  Formation of peripheral pulse contour in man. , 1956, Journal of applied physiology.

[8]  N Bom,et al.  Characterization of plaque components and vulnerability with intravascular ultrasound elastography. , 2000, Physics in medicine and biology.

[9]  Is ultrasonic imaging a sensitive indicator of spatially varying elastic anisotropy? , 2001, 2001 IEEE Ultrasonics Symposium. Proceedings. An International Symposium (Cat. No.01CH37263).

[10]  R S Reneman,et al.  Non-invasive measurement of mechanical properties of arteries in health and disease , 1999, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[11]  C T Lancée,et al.  Intravascular elasticity imaging using ultrasound: feasibility studies in phantoms. , 1997, Ultrasound in medicine & biology.

[12]  Den Hartog.  Advanced Strength of Materials , 1952 .

[13]  E L Madsen,et al.  Oil-in-gelatin dispersions for use as ultrasonically tissue-mimicking materials. , 1982, Ultrasound in medicine & biology.

[14]  C. D. de Korte,et al.  Intravascular ultrasound elastography in human arteries: initial experience in vitro. , 1998, Ultrasound in medicine & biology.

[15]  C. R. Hill,et al.  Measurement of soft tissue motion using correlation between A-scans. , 1982, Ultrasound in medicine & biology.

[16]  R. D. Bauer,et al.  The Arterial system : dynamics, control theory, and regulation , 1978 .

[17]  B. Garra,et al.  Elastography of breast lesions: initial clinical results. , 1997, Radiology.

[18]  T. Hall,et al.  2-D companding for noise reduction in strain imaging , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[19]  D. A. Christopher,et al.  A wall-less vessel phantom for Doppler ultrasound studies. , 1995, Ultrasound in medicine & biology.

[20]  Y. Summa.  Determination of the Tangential Elastic Modulus of Human Arteries In Vivo , 1978 .

[21]  Insana,et al.  Maximum-likelihood approach to strain imaging using ultrasound , 2000, The Journal of the Acoustical Society of America.

[22]  E. Madsen,et al.  Tissue mimicking materials for ultrasound phantoms. , 1978, Medical physics.

[23]  L. Wilson,et al.  Ultrasonic measurement of small displacements and deformations of tissue. , 1982, Ultrasonic imaging.

[24]  S. Levinson,et al.  Sonoelastic determination of human skeletal muscle elasticity. , 1995, Journal of biomechanics.

[25]  Terminology for the definition of arterial elastic properties. , 1999 .

[26]  J. Ophir,et al.  Reduction of Image Noise in Elastography , 1993 .

[27]  C. R. Hill,et al.  Ultrasonic study of in vivo kinetic characteristics of human tissues. , 1986, Ultrasound in medicine & biology.

[28]  Jonathan Ophir,et al.  Performance Optimization in Elastography: Multicompression with Temporal Stretching , 1996 .

[29]  T. Krouskop,et al.  Phantom materials for elastography , 1997, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[30]  M. Bilgen,et al.  Elastostatics of a spherical inclusion in homogeneous biological media. , 1998, Physics in medicine and biology.

[31]  E. Volterra,et al.  Advanced strength of materials , 1971 .

[32]  P. Bland,et al.  Quantitative tissue motion analysis of digitized M-mode images: gestational differences of fetal lung. , 1990, Ultrasound in medicine & biology.