Detection and isolation of SARS‐CoV‐2 Eta variant from the international travelers and local residents of India

International travel has been the major source for the rapid spread of new SARS‐CoV‐2 variants across the globe. During SARS‐CoV‐2 genomic surveillance, a total of 212 SARS‐CoV‐2 positive clinical specimens were sequenced using next‐generation sequencing. A complete SARS‐CoV‐2 genome could be retrieved from 90 clinical specimens. Of them, 14 sequences belonged to the Eta variant from clinical specimens of international travelers (n = 12) and local residents (n = 2) of India, and 76 belonged to other SARS‐CoV‐2 variants. Of all the Eta‐positive specimens, the virus isolates were obtained from the clinical specimens of six international travelers. Many variants of interest have been found to cause substantial community transmission or cluster infections. The detection of this variant with lethal E484K mutation across the globe and India necessitates persistent genomic surveillance of the SARS‐CoV‐2 variants, which would aid in taking preventive action.

[1]  Sunando Roy,et al.  Post-Vaccination Coronavirus Disease 2019: A Case-Control Study and Genomic Analysis of 119 Breakthrough Infections in Partially Vaccinated Individuals , 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[2]  P. Dormitzer,et al.  BNT162b2-elicited neutralization of B.1.617 and other SARS-CoV-2 variants , 2021, Nature.

[3]  T. Caspari,et al.  The Spike of Concern—The Novel Variants of SARS-CoV-2 , 2021, Viruses.

[4]  Job vacancy at the European Centre for Disease Prevention and Control (ECDC) , 2021, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[5]  Atanu Basu,et al.  First isolation of SARS-CoV-2 from clinical samples in India. , 2020, The Indian journal of medical research.

[6]  P. Shil,et al.  Complete genome sequencing of Kaisodi virus isolated from ticks in India belonging to Phlebovirus genus, family Phenuiviridae. , 2019, Ticks and tick-borne diseases.

[7]  C. Dolea,et al.  World Health Organization , 1949, International Organization.