Block by MOPS reveals a conformation change in the CFTR pore produced by ATP hydrolysis.
暂无分享,去创建一个
[1] J. Rommens,et al. ATPase Activity of the Cystic Fibrosis Transmembrane Conductance Regulator* , 1996, The Journal of Biological Chemistry.
[2] M. Drumm,et al. Slow conversions among subconductance states of cystic fibrosis transmembrane conductance regulator chloride channel. , 1996, Biophysical journal.
[3] M. Welsh,et al. Structural and functional similarities between the nucleotide-binding domains of CFTR and GTP-binding proteins. , 1995, Biophysical journal.
[4] P. Pedersen,et al. The First Nucleotide Binding Fold of the Cystic Fibrosis Transmembrane Conductance Regulator Can Function as an Active ATPase (*) , 1995, The Journal of Biological Chemistry.
[5] M. Welsh,et al. Pyrophosphate Stimulates Wild-type and Mutant Cystic Fibrosis Transmembrane Conductance Regulator Cl− Channels (*) , 1995, The Journal of Biological Chemistry.
[6] K. Gunderson,et al. Conformational states of CFTR associated with channel gating: The role of ATP binding and hydrolysis , 1995, Cell.
[7] R. Frizzell,et al. Regulation of CFTR Cl- channel gating by ADP and ATP analogues , 1995, The Journal of general physiology.
[8] M. Welsh,et al. The Two Nucleotide-binding Domains of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Have Distinct Functions in Controlling Channel Activity (*) , 1995, The Journal of Biological Chemistry.
[9] Anatoli N. Lopatin,et al. Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification , 1994, Nature.
[10] A. Nairn,et al. Regulation of CFTR channel gating. , 1994, Trends in biochemical sciences.
[11] Henry A. Lester,et al. Novel pore-lining residues in CFTR that govern permeation and open-channel block , 1994, Neuron.
[12] K. Gunderson,et al. Effects of pyrophosphate and nucleotide analogs suggest a role for ATP hydrolysis in cystic fibrosis transmembrane regulator channel gating. , 1994, The Journal of biological chemistry.
[13] G. Nagel,et al. Regulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysis. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[14] J. Wine,et al. CFTR in Calu-3 human airway cells: channel properties and role in cAMP-activated Cl- conductance. , 1994, The American journal of physiology.
[15] M. Welsh,et al. Effect of ATP concentration on CFTR Cl- channels: a kinetic analysis of channel regulation. , 1994, Biophysical journal.
[16] A. Nairn,et al. Coupling of CFTR Cl− channel gating to an ATP hydrolysis cycle , 1994, Neuron.
[17] M. Welsh,et al. Stoichiometry of recombinant cystic fibrosis transmembrane conductance regulator in epithelial cells and its functional reconstitution into cells in vitro. , 1994, The Journal of biological chemistry.
[18] L. Tsui,et al. Multi-ion pore behaviour in the CFTR chloride channel , 1993, Nature.
[19] M. Welsh,et al. Interaction of nucleotides with membrane-associated cystic fibrosis transmembrane conductance regulator. , 1993, The Journal of biological chemistry.
[20] J. Riordan,et al. Voltage-dependent block of the cystic fibrosis transmembrane conductance regulator Cl- channel by two closely related arylaminobenzoates , 1993, The Journal of general physiology.
[21] M. Welsh,et al. Mutations in CFTR associated with mild-disease-form CI- channels with altered pore properties , 1993, Nature.
[22] M. Welsh,et al. Regulation by ATP and ADP of CFTR chloride channels that contain mutant nucleotide-binding domains. , 1992, Science.
[23] F. Collins,et al. Cystic fibrosis: molecular biology and therapeutic implications. , 1992, Science.
[24] Matthew P. Anderson,et al. Cystic fibrosis transmembrane conductance regulator: A chloride channel with novel regulation , 1992, Neuron.
[25] Matthew P. Anderson,et al. Nucleoside triphosphates are required to open the CFTR chloride channel , 1991, Cell.
[26] Matthew P. Anderson,et al. Expression of cystic fibrosis transmembrane conductance regulator corrects defective chloride channel regulation in cystic fibrosis airway epithelial cells , 1990, Nature.
[27] N. Suzuki,et al. Blockage of chloride channels by HEPES buffer , 1987, Proceedings of the Royal Society of London. Series B. Biological Sciences.
[28] A. Woodhull,et al. Ionic Blockage of Sodium Channels in Nerve , 1973, The Journal of general physiology.
[29] J. Riordan,et al. The cystic fibrosis transmembrane conductance regulator. , 1993, Annual review of physiology.