Murine epidermal Langerhans cells as a model to study tissue dendritic cells.

[1]  M. Plumb,et al.  Hemopoietic stem cell inhibitor (SCI/MIP-1 alpha) also inhibits clonogenic epidermal keratinocyte proliferation. , 1993, The Journal of investigative dermatology.

[2]  G. Schuler,et al.  Cytokine gene expression in murine epidermal cell suspensions: interleukin 1 beta and macrophage inflammatory protein 1 alpha are selectively expressed in Langerhans cells but are differentially regulated in culture , 1992, The Journal of experimental medicine.

[3]  R. Steinman,et al.  Identification of proliferating dendritic cell precursors in mouse blood , 1992, The Journal of experimental medicine.

[4]  P. Holt,et al.  Studies on the surface phenotype and functions of dendritic cells in parenchymal lung tissue of the rat. , 1992, Immunology.

[5]  A. Enk,et al.  Early molecular events in the induction phase of contact sensitivity. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[6]  A. Reske-Kunz,et al.  Biochemical properties of MHC class II molecules endogenously synthesized and expressed by mouse Langerhans cells , 1991, European journal of immunology.

[7]  S. Aiba,et al.  The ability of cultured Langerhans cells to process and present protein antigens is MHC-dependent. , 1991, Journal of immunology.

[8]  G. Schuler,et al.  Class II major histocompatibility complex molecules of murine dendritic cells: synthesis, sialylation of invariant chain, and antigen processing capacity are down-regulated upon culture. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[9]  R. Steinman,et al.  The dendritic cell system and its role in immunogenicity. , 1991, Annual review of immunology.

[10]  G. Schuler Epidermal Langerhans Cells , 1990 .

[11]  J. Streilein,et al.  Ultraviolet B light-induced alterations in epidermal Langerhans cells are mediated in part by tumor necrosis factor-alpha. , 1990, Photodermatology, photoimmunology & photomedicine.

[12]  R. Steinman,et al.  Antigen processing by epidermal Langerhans cells correlates with the level of biosynthesis of major histocompatibility complex class II molecules and expression of invariant chain , 1990, The Journal of experimental medicine.

[13]  G. Schuler,et al.  Disappearance of certain acidic organelles (endosomes and Langerhans cell granules) accompanies loss of antigen processing capacity upon culture of epidermal Langerhans cells , 1990, The Journal of experimental medicine.

[14]  R. Steinman,et al.  Migration and maturation of Langerhans cells in skin transplants and explants , 1990, The Journal of experimental medicine.

[15]  R. Steinman,et al.  Dendritic cells pulsed with protein antigens in vitro can prime antigen- specific, MHC-restricted T cells in situ [published erratum appears in J Exp Med 1990 Oct 1;172(4):1275] , 1990, The Journal of experimental medicine.

[16]  E. Wright,et al.  Identification and characterization of an inhibitor of haemopoietic stem cell proliferation , 1990, Nature.

[17]  G. Schuler,et al.  Tumor necrosis factor alpha maintains the viability of murine epidermal Langerhans cells in culture, but in contrast to granulocyte/macrophage colony-stimulating factor, without inducing their functional maturation , 1990, The Journal of experimental medicine.

[18]  J. Streilein,et al.  In vitro evidence that Langerhans cells can adopt two functionally distinct forms capable of antigen presentation to T lymphocytes. , 1989, Journal of immunology.

[19]  R. Steinman,et al.  An antigen-independent contact mechanism as an early step in T cell- proliferative responses to dendritic cells , 1989, The Journal of experimental medicine.

[20]  R. Steinman,et al.  A small number of anti-CD3 molecules on dendritic cells stimulate DNA synthesis in mouse T lymphocytes , 1989, The Journal of experimental medicine.

[21]  R. Steinman,et al.  Presentation of exogenous protein antigens by dendritic cells to T cell clones. Intact protein is presented best by immature, epidermal Langerhans cells , 1989, The Journal of experimental medicine.

[22]  H. Mcdevitt,et al.  T cell receptors in murine autoimmune diseases. , 1989, Annual review of immunology.

[23]  G. Schuler,et al.  Granulocyte/macrophage colony-stimulating factor and interleukin 1 mediate the maturation of murine epidermal Langerhans cells into potent immunostimulatory dendritic cells , 1988, The Journal of experimental medicine.

[24]  R. Steinman,et al.  Granulocyte/macrophage colony-stimulating factor is essential for the viability and function of cultured murine epidermal Langerhans cells , 1987, The Journal of experimental medicine.

[25]  R. Steinman,et al.  Immunologic properties of purified epidermal Langerhans cells. Distinct requirements for stimulation of unprimed and sensitized T lymphocytes , 1986, The Journal of experimental medicine.

[26]  R. Steinman,et al.  Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitro , 1985, The Journal of experimental medicine.